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The study reported an electrochemically promoted asymmetric hydrogen transfer reaction of 2,2,2-trifluoroacetophenone with a chiral Ru complex. ()-α-(Trifluoromethyl) benzyl alcohol with a 96% yield and 94% ee could be obtained with only a 0.5 F mol charge amount at room temperature and normal pressure.
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http://dx.doi.org/10.1021/acs.joc.1c01030 | DOI Listing |
Nature
September 2025
Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA.
Neural activity is increasingly recognized as a crucial regulator of cancer growth. In the brain, neuronal activity robustly influences glioma growth through paracrine mechanisms and by electrochemical integration of malignant cells into neural circuitry via neuron-to-glioma synapses. Outside of the central nervous system, innervation of tumours such as prostate, head and neck, breast, pancreatic, and gastrointestinal cancers by peripheral nerves similarly regulates cancer progression.
View Article and Find Full Text PDFJ Am Chem Soc
September 2025
Department of Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.
Alternating current (AC) electrolysis offers a promising strategy for modulating redox states in metal-catalyzed reactions, yet its mechanistic basis remains poorly understood. Here, we uncover how AC frequency synchronizes with key steps in a Ni-catalyzed cross-coupling cycle to control product selectivity between C-N and C-C coupling. We show that optimal C-N selectivity arises from minimizing the exposure of a key intermediate, Ni(Ar)Br, to reducing conditions that otherwise promote off-cycle Ni species and undesired C-C homocoupling.
View Article and Find Full Text PDFJ Hazard Mater
September 2025
School of Ecology and Environment, Zhengzhou University, Zhengzhou 450001, China; Henan Key Laboratory of Environmental Chemistry and Low Carbon Technology, Zhengzhou 450001, China. Electronic address:
Solid electrolyte cell is a novel gas purification approach, which has unique superiority in simultaneous nitrogen oxides (NO) and volatile organic compounds (VOCs) removal. The development of effective electrode materials and the comprehensive understanding of reaction mechanisms are essential to advancing this technology. In this study, LaPrBaNiO (x = 0, 0.
View Article and Find Full Text PDFJ Colloid Interface Sci
September 2025
Guangxi Key Laboratory of Electrochemical Energy Materials, School of Chemistry and Chemical Engineering, Guangxi University, 100 Daxue Road, Nanning 530004, China. Electronic address:
The 5-hydroxymethylfurfural electrooxidation reaction (HMFOR) stands out due to the value-added production and mild conditions. However, its catalytic efficiency is hampered by sluggish kinetics. Herein, with a focus on optimizing the adsorption and activation of reaction molecules, a CoN-WN heterostructure catalyst is constructed for efficient HMFOR.
View Article and Find Full Text PDFSmall
September 2025
School of Chemistry and Chemical Engineering, Key Lab of Fuel Cell Technology of Guangdong Province, South China University of Technology, Guangzhou, 510641, China.
Aggregation-induced electrochemiluminescence (AIECL) is a promising strategy for enhancing electrochemiluminescence (ECL) efficiency by minimizing energy loss of excited-state ECL emitters. However, rational design of high-efficiency AIECL emitters is hindered by limited mechanistic understanding and an unclear structure-performance relationship. To address this, four supramolecular coordination frameworks (SCFs) with varying π-bridge structures are synthesized using pyridine-functionalized tetraphenylethene (TPE) as the ligand and Pt(II) as the coordination center.
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