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(Reinhardt, 1837) has been identified as a target species for investigating the effects of climate change on population patterns in coastal Arctic ecosystems. The complete mitochondrial genome of the was first sequenced in this study. The mitochondrial genome was sequenced with 16,524 bp in length, including 13 protein-coding genes, 22 transfer RNA genes, two ribosomal RNA genes, and a putative control region. All the protein-coding genes employed ATG as the start codon except COI using GTG. Three stop codons were observed in the protein-coding genes, including TAA, TAG and T. In addition, phylogenetic tree can provide further genetic analysis for this important species.
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http://dx.doi.org/10.1080/23802359.2019.1689192 | DOI Listing |
Hypertension
September 2025
Department of Obstetrics and Gynecology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu (Z.W.).
Background: Early-onset preeclampsia poses significant risks to maternal and fetal health, necessitating a deeper understanding of its molecular mechanisms and effective therapeutic strategies.
Methods: Utilizing data from genome-wide association study and Mendelian randomization analysis, we investigated the relationship between mitochondrial DNA copy number and preeclampsia. Transcriptome sequencing, in vitro experiments, and animal studies were conducted to explore the roles of SENP3 and SETD7 in preeclampsia pathogenesis.
Wellcome Open Res
September 2025
Tree of Life, Wellcome Sanger Institute, Hinxton, England, UK.
We present a genome assembly from a male specimen of (Arthropoda; Insecta; Lepidoptera; Geometridae). The assembly contains two haplotypes with total lengths of 575.96 megabases and 573.
View Article and Find Full Text PDFWellcome Open Res
September 2025
Tree of Life, Wellcome Sanger Institute, Hinxton, England, UK.
We present a genome assembly from a male specimen of (Black Hairstreak; Arthropoda; Insecta; Lepidoptera; Lycaenidae). The assembly contains two haplotypes with total lengths of 869.86 megabases and 870.
View Article and Find Full Text PDFWellcome Open Res
September 2025
Department of Biology, University of Oxford, Oxford, England, UK.
We present a genome assembly from a female specimen of (flea beetle; Arthropoda; Insecta; Coleoptera; Chrysomelidae). This was a triploid specimen and one subgenome was assembled. The genome sequence has a total length of 1,003.
View Article and Find Full Text PDFClin Genet
September 2025
Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
LONP1 encodes a mitochondrial protease essential for protein quality control and metabolism. Variants in LONP1 are associated with a diverse and expanding spectrum of disorders, including Cerebral, Ocular, Dental, Auricular, and Skeletal anomalies syndrome (CODAS), congenital diaphragmatic hernia (CDH), and neurodevelopmental disorders (NDD), with some individuals exhibiting features of mitochondrial encephalopathy. We report 16 novel LONP1 variants identified in 16 individuals (11 with NDD, 5 with CDH), further expanding the clinical spectrum.
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