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Purpose: To report the use of Spectralis High Magnification Module (HMM) as part of multimodal imaging in Multiple Evanescent White Dot Syndrome (MEWDS).
Observations: HMM imaging showed a blurry mosaic pattern corresponding to MEWDS-related photoreceptors' lesions. These abnormalities remained detectable at later stages of the disease while other imaging modalities were negative.
Conclusions And Importance: HMM can be a useful technique to monitor the structure of the outer retina during the different stages of MEWDS.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218256 | PMC |
http://dx.doi.org/10.1016/j.ajoc.2020.100727 | DOI Listing |
Life Sci Space Res (Amst)
August 2025
The Houston Methodist Research Institute, Houston Methodist Hospital, Houston, TX, United States; Texas A&M School of Medicine, Bryan, TX, United States; Boston University Chobanian & Avedisian School of Medicine, Boston, United States; Center for Space Medicine, Baylor College of Medicine, Houston,
Spaceflight presents unique challenges to ocular health which must be addressed when considering future long-term missions to Mars and beyond, specifically with increased risk to the anterior segment of the eye. While the posterior segment has been heavily researched via examinations with Heidelberg's Spectralis Optical Coherence Tomography (OCT)2 Module aboard the International Space Station (ISS), evaluation of the anterior segment is not as extensively performed. Despite the capabilities of the Spectralis, which allows for anterior segment imaging via the Anterior Segment Module (ASM), transforming the OCT into an Anterior Segment OCT (AS-OCT), there is limited information available regarding anterior segment effects due to microgravity and spaceflight.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
August 2025
Department of Ophthalmology and Visual Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, United States.
Purpose: The purpose of this study was to investigate longitudinal thickness changes of the peripapillary tissues in tree shrew eyes with induced high myopia from juvenile age to early adulthood.
Methods: Juvenile tree shrews were randomly assigned to either a control group (16 eyes, 8 animals) or a group with binocular -10 diopter (D) lens wear (18 eyes, 9 animals). Refraction, biometry, and optical coherence tomography scans centered on the optic nerve head (ONH) were obtained weekly for 19 weeks.
Int J Ophthalmol
July 2025
Department of Ophthalmology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
Aim: To elucidate the manifestations and associated complications observed in patients with intraocular silicone oil (SO) emulsification through multiple imaging modalities.
Methods: This single-center, observational, retrospective study included 116 patients who underwent pars plana vitrectomy (PPV) with SO injection for retinal detachment (RD), followed by subsequent SO removal at the Second Hospital of Hebei Medical University from January 2013 to January 2023. Comprehensive records of ophthalmic examinations utilizing multiple imaging techniques were maintained.
Sci Rep
June 2025
Department of Ophthalmology, LMU University Hospital, Ludwig-Maximilians-Universität München, Mathildenstraße 8, 80336, Munich, Germany.
Optical Coherence Tomography Angiography (OCTA) has become an essential non-invasive imaging technique for high-resolution visualization of retinal microvasculature. This study evaluates the performance of a novel Swept-Source OCTA device, Intalight DREAM, compared to established systems: Heidelberg Spectralis, Topcon Triton, and Zeiss Cirrus. We assessed acquisition time and microvascular parameters in the superficial (SCP) and deep (DCP) capillary plexuses using the OCTA Vascular Analyser algorithm for standardized image analysis across devices on 30 eyes from 15 healthy participants.
View Article and Find Full Text PDFOphthalmol Sci
April 2025
Bascom Palmer Eye Institute, University of Miami, Miami, Florida.
Purpose: To evaluate the repeatability of OCT angiography (OCTA) vessel density measurements using fractal analysis in the macula and optic nerve head (ONH) regions.
Design: A prospective longitudinal observational cohort study.
Participants: One hundred sixteen eyes from 71 primary open-angle glaucoma patients with valid macula OCTA scans and 91 eyes from 59 primary open-angle glaucoma patients with valid ONH OCTA scans, with 53 patients contributing scans for both regions.