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Article Abstract
Five new -pimarane diterpenoids 16-nor-2-oxopimar-8(14)-ene-15,19-dial (), 16-nor-2α,19-dihydroxypimar-8-en-15-al (), 3--acetyldarutigenol (), 19-acetylkirenol (), -16-nor-3,15-dihydroxypimar-8(14)-ene () were isolated and characterized from the ethanol extract of . Their structures were elucidated on the basis of spectroscopic analysis. The absolute configuration of C-15 in compounds and was assigned using Snatzke's method. All these compounds were assessed for their anti-inflammatory potential by measuring the inhibitory effects on NO production in LPS-induced RAW 264.7 macrophage cells and compound showed significantly inhibitory activity with IC value of 5.9 μM.
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| http://dx.doi.org/10.1080/14786419.2019.1656627 | DOI Listing |
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