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Molecular probes suitable for different fluorescence imaging technologies can meet the requirements of different scientific research in biological applications. In this work, a naphthalimide-cyanine-based sulfonamide was used to specifically visualize the glutathione of mouse tissues with a two-photon manner for the naphthalimide moiety and a near-infrared manner for the cyanine moiety, respectively. The results showed that this probe served as a dual-model tissue-imaging agent for visualization of glutathione with around 200 μm imaging depth in a two-photon manner and 120 μm imaging depth in a near-infrared manner, which provided a model for tissue imaging in the visible and near-infrared channels.
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http://dx.doi.org/10.1021/acs.analchem.9b02458 | DOI Listing |
Int J Gen Med
September 2025
Department of Dermatology, Hangzhou Third People's Hospital, Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, People's Republic of China.
Background: Nodular hidradenoma (NH) is a rare benign adnexal tumor originating from sweat glands, often misdiagnosed due to nonspecific clinical manifestations. Ultrasonography (US) plays a critical role in the diagnosis of skin tumors, yet systematic descriptions of its sonographic features remain limited.
Objective: This study aims to investigate the very-high-frequency (VHF) characteristics of eccrine nodular hidradenoma (ENH) and establish key imaging criteria to differentiate it from other cutaneous/subcutaneous lesions.
Front Immunol
September 2025
Department of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Introduction: Anti-N-methyl-D-aspartate receptor (NMDA-R) encephalitis is a neuropsychiatric disorder with additional psychiatric features caused by NMDA-R immunoglobulin G (IgG) antibodies in cerebrospinal fluid (CSF). This report presents the follow-up of a patient in whom we assumed mild NMDA-R encephalitis in the first psychotic episode.
Case Study: A patient with a prior episode of an acute polymorphic psychotic syndrome relapsed five and a half years later following a severe COVID-19 infection.
Case Rep Med
September 2025
Oral and Maxillofacial Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Oral and maxillofacial space infection (OMSI) progresses rapidly, and when combined with diabetic ketoacidosis (DKA), it can become a serious and life-threatening condition. Cases of OMSI with concurrent DKA are relatively rare. This case report describes a young man who developed OMSI caused by methicillin-resistant in the setting of DKA.
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August 2025
Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Introduction: Synovial sarcoma (SS) is one of the most prevalent malignant soft tissue sarcomas in children and adolescents. Pediatric populations often present with atypical features, complicating the differentiation from benign intramuscular venous malformations (VMs).
case Presentation: An 11-year-old male with a four-year history of progressive right plantar pain and a compressible intramuscular mass.
J Surg Case Rep
September 2025
Department of Obstetrics and Gynaecology, Irrua Specialist Teaching Hospital, KM 87, Benin-Auchi Road, P.M.B. 08, Irrua 310114, Edo State, Nigeria.
Clitoral cyst is an epidermal inclusion cyst that results from invagination of the epidermis into the dermis or subcutaneous tissue. It commonly occurs following trauma from female genital mutilation (FGM), with presentation typically in childhood or the peripubertal period. Later, presentations often arise due to the asymptomatic nature of the condition and the associated stigma.
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