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To compare interrater reliability and the time-efficiency for the water displacement method, figure-of-eight method, and circumference measurements of the ankle and foot, and to investigate concurrent validity of the figure-of-eight method and circumference measurements with the water displacement method. Thirty patients (21 women and 9 men) with primary or secondary lower limb lymphedema were evaluated twice. The volume of the foot and ankle was measured in three different ways: water displacement with a volumeter, figure-of-eight method, and circumference measurements at the level of the malleoli and metatarsals with a tapeline. The intraclass correlation coefficients (ICCs) ranged from good to excellent for all measurements (ICCs = 0.99 for water displacement; 0.94 for figure-of-eight; 0.80 and 0.79 for circumference measurement at malleolus and metatarsals). More time was needed to perform the water displacement method than the figure-of-eight method and the circumference measurements ( < 0.001). There was a statistically significant moderate correlation between the water displacement method and the figure-of-eight method ( = 0.65; < 0.001), whereas the correlation coefficient between water displacement method and circumference measurements at malleolus and metatarsals was weak ( = 0.51, < 0.001 and = 0.34, = 0.06, respectively). Compared to the water displacement method, reliability of the figure-of-eight method is comparable, time-efficiency is better and concurrent validity is acceptable. So, in clinical practice, the figure-of-eight method is a good alternative for the water displacement method to evaluate the volume of the foot and ankle.
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http://dx.doi.org/10.1089/lrb.2018.0045 | DOI Listing |
J Chem Phys
September 2025
Department of Chemistry, Chicago Center for Theoretical Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, 5735 S. Ellis Ave., SCL 123, Chicago, Illinois 60637, USA.
Molecular dynamics simulations are essential for studying complex molecular systems, but their high computational cost limits scalability. Coarse-grained (CG) models reduce this cost by simplifying the system, yet traditional approaches often fail to maintain dynamic consistency, compromising their reliability in kinetics-driven processes. Here, we introduce an adversarial training framework that aligns CG trajectory ensembles with all-atom (AA) reference dynamics, ensuring both thermodynamic and kinetic fidelity.
View Article and Find Full Text PDFWater Res
September 2025
State Key Laboratory of Soil Pollution Control and Safety, Department of Environmental Science, Zhejiang University, Hangzhou 310058, China; Future Environment Laboratory, Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing 314100, China. Electronic address:
Accelerating the rate-limiting surface Fe(III)/Fe(II) redox cycling is pivotal for efficient iron-mediated Fenton-like decontamination, yet conventional reductants (e.g., toxic hydroxylamine, thiosulfate) suffer from secondary toxicity, self-quenching, and heavy metal leaching.
View Article and Find Full Text PDFEcology
September 2025
U.S. Geological Survey, Pennsylvania Cooperative Fish and Wildlife Research Unit, The Pennsylvania State University, University Park, Pennsylvania, USA.
Invasive species are drivers of ecological change with the potential to reshape the structure and function of terrestrial and aquatic ecosystems. The invasive flathead catfish (Pylodictis olivaris) is an opportunistic predator that has established a rapidly growing population in the Susquehanna River, Pennsylvania, USA, since they were first detected in 2002. Although the predatory effects of invasive catfishes on native fish communities have been documented, the effects of invasion on riverine food webs are poorly understood.
View Article and Find Full Text PDFVet Clin North Am Food Anim Pract
September 2025
Department of Animal Science, Colorado State University, 350 West Pitkin Street, Fort Collins, USA. Electronic address:
The current article describes select nutritional metabolic disorders that can impact the health and well-being of beef and dairy cattle. These include: Subclinical or clinical acidosis that can lead to rumen, hind gut, or systemic acidosis. Acidosis can disrupt epithelial barrier function in the rumen and hindgut, enabling bacteria to enter the portal vein and form liver abscesses.
View Article and Find Full Text PDFGlob Public Health
December 2025
Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Canada.
Climate-related extreme weather events (EWE) affect sexual and reproductive health and rights (SRHR) outcomes through complex and multi-level pathways. These include institutional-level effects on health systems, such as damaged health infrastructure and roads, barriers to retaining qualified health and care workers, as well as healthcare access barriers due to increased economic precarity, displacement and migration. Furthermore, EWE effects on SRHR disproportionately affect marginalised communities.
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