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The magnetic anchoring guidance system (MAGS) is one of the most promising technological innovations in minimally invasive surgery and consists in two magnetic elements matched through the abdominal or thoracic wall. The internal magnet can be inserted into the abdominal or chest cavity through a small single incision and then moved into position by manipulating the external component. In addition to a video camera system, the inner magnetic platform can house remotely controlled surgical tools thus reducing instruments fencing, a serious inconvenience of the uniportal access. The latest prototypes are equipped with self-light-emitting diode (LED) illumination and a wireless antenna for signal transmission and device controlling, which allows bypassing the obstacle of wires crossing the field of view (FOV). Despite being originally designed for laparoscopic surgery, the MAGS seems to suit optimally the characteristics of the chest wall and might meet the specific demands of video-assisted thoracic surgery (VATS) surgery in terms of ergonomics, visualization and surgical performance; moreover, it involves less risks for the patients and an improved aesthetic outcome.
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http://dx.doi.org/10.21037/jovs.2017.01.13 | DOI Listing |
Anal Chem
September 2025
School of Materials Science and Engineering, Shanghai University of Engineering Science, Shanghai 201620, China.
Point-of-care (POC) detection of prostate-specific antigen (PSA) is critical for the early screening and monitoring of prostate cancer (PCa), which facilitates timely intervention and personalized treatment. However, existing POC platforms suffer from inadequate detection sensitivities, susceptibility to matrix interference, and complex sample pretreatment. To address these issues, we proposed a naked-eye and colorimetric sensing platform based on magnetic nanozyme (FeO@ZIF-67@Pt) integrated with a tetrahedral DNA framework (TDF) and alkaline phosphatase (ALP)-triggered hydrolysis reaction for PSA detection with superior sensing performances.
View Article and Find Full Text PDFNature
September 2025
Institute for Geophysics, Jackson School of Geosciences, University of Texas at Austin, Austin, TX, USA.
For rocky planets, the presence of a solid inner core has notable implications on the composition and thermal evolution of the core and on the magnetic history of the planet. On Mars, geophysical observations have confirmed that the core is at least partially liquid, but it is unknown whether any part of the core is solid. Here we present an analysis of seismic data acquired by the InSight mission, demonstrating that Mars has a solid inner core.
View Article and Find Full Text PDFRSC Adv
August 2025
School of Instrumentation and Optoelectronic Engineering, Beihang University Beijing 100191 China
To investigate the anti-relaxation performance of FOTS-modified OTS coatings on the inner walls of cesium (Cs) atomic cell, this study employs molecular dynamics (MD) simulations to explore the self-assembly process of FOTS-modified OTS molecular chains on the SiO (001) surface and evaluates the effects of FOTS chain amounts, water molecule content, and temperature on the diffusion behavior of Cs atoms. Results show that the optimized interface model of the FOTS-modified OTS coating and SiO substrate achieves thermodynamic and energetic equilibrium under the conditions of 25 °C and 2000 ps. The film formation process of FOTS-modified OTS chains on SiO surfaces involves three distinct stages: initial anchoring, conformational rearrangement, and structural relaxation and equilibrium configuration.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
September 2025
Key Laboratory of Magnetic Molecules and Magnetic Information Material of Ministry of Education, School of Chemistry and Material Science, Shanxi Normal University, Taiyuan, 030006, P.R. China.
The strategic modulation of proton transport kinetics and precise control of migration energy barriers in metal-organic frameworks (MOFs) are essential for developing next-generation proton conductors. Inspired by biological proton channels, this study introduces a dynamic regulation strategy by keto-enol tautomerism to reconcile the intrinsic trade-off between low activation energy (E) and sustained proton mobility. We successfully construct a hierarchical proton conductive system (denoted as FU@MOF-808-SOH) by integrating 5-fluorouracil (5-FU) molecules into sulfonic-functionalized MOF-808 through a two-step post-synthetic modification.
View Article and Find Full Text PDFTalanta
August 2025
Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Public Health, Wuhan University of Science and Technology, Wuhan, 430065, China. Electronic address:
MicroRNAs (miRNAs) serves as a crucial biomarker for early cancer diagnosis, and dual-target miRNA detection significantly enhances diagnostic accuracy. However, the uncontrollable uniformity of multi-capture probe modifications, limited electrode sites, and high sample consumption restrict the advancement of electrochemical biosensors in clinical diagnostics. In this work, an integrated microdroplet chip electrochemical biosensor has been ingeniously developed, including TiO nanorods modified by Au nanoparticles vertically arranged on the FTO as the working electrode, which exhibits high electron transfer efficiency and abundant anchoring sites for capture probes; A Y-shaped probe was designed with one end immobilized via Au-S covalent bonding while the two free arms enabled simultaneous dual-target miRNA recognition; By employing Au/TiO-FTO as both the substrate for a custom micro-detection chamber and the working electrode, coupled with catalytic hairpin assembly (CHA), the sensor achieves ultrahigh-precision trace-level detection of dual miRNAs.
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