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Background: Although the mechanism of migraine is regarded as a functional disorder of the brain, numerous studies have reported that migraine is closely associated with vascular system abnormalities.
Case Reports: We describe a 19-year-old female with recurrent migraine attacks and typical aura for 7 years. MRI showed multiple stroke lesions in the posterior circulation. Moreover, a pseudoaneurysm (1.9 × 1.4 cm) originating from the left vertebral artery was observed on four-vessel angiography. Multiple microembolic signals (MES) were repeatedly observed in the basilar artery using 30-minute transcranial Doppler monitoring. Interestingly, MES and her typical migrainous symptoms disappeared simultaneously with removal of the pseudoaneurysm.
Discussion: This case supports the fact that microemboli play a pivotal role in the development of migraine attacks.
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http://dx.doi.org/10.1177/0333102412441722 | DOI Listing |
Neurology
September 2025
Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, United Kingdom.
Background And Objectives: Cerebrovascular reactivity (CVR) is an indicator of cerebrovascular health, and its signature in familial frontotemporal dementia (FTD) remains unknown. The primary aim was to investigate CVR in genetic FTD using an fMRI index of vascular contractility termed resting-state fluctuation amplitudes (RSFAs) and to assess whether RSFA differences are moderated by age. A secondary aim was to study the relationship between RSFA and cognition.
View Article and Find Full Text PDFBone Joint Res
September 2025
Legal Medicine Research Center, Iran Legal Medicine Organization, Tehran, Iran.
Aims: The significance of periosteal vessels in the healing of tibial shaft fractures is well-established. However, the gross anatomical patterns and differential distribution of these vessels on the medial versus lateral surface of the tibial shaft have not been thoroughly described. This study aimed to illustrate the comparative anatomy of periosteal circulation on the medial versus lateral surface of the tibial shaft, where tibial plates are commonly applied.
View Article and Find Full Text PDFFront Neurol
August 2025
Department of Neurology, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, China.
Introduction: The triglyceride-glucose (TyG) index, a robust surrogate marker of metabolic dysregulation reflecting both insulin resistance and lipid-glucose homeostasis, has emerged as a significant predictor of cerebrovascular outcomes. Given the critical role of metabolic-nutritional status in post-stroke recovery, we supposed that the TyG index may predict the prognosis of ischemic stroke patients who underwent thrombectomy in the posterior circulation.
Methods: We studied 60 patients with cerebral infarction who underwent emergency posterior circulation interventional thrombectomy at a comprehensive stroke center from January 2018 to July 2024.
Front Cell Dev Biol
August 2025
Department of Anatomy, College of Basic Medicine, Dalian Medical University, Dalian, Liaoning, China.
Objective: The myodural bridge complex (MDBC) is a tendon-like structure highly conserved during vertebrate evolution, suggesting it plays an important physiological role. Substantial evidence indicates that the MDBC may contribute to cerebrospinal fluid (CSF) circulation by generating mechanical force. Studying its developmental process may offer new insights into CSF dynamics and lead to improved strategies for diagnosing and treating neurodegenerative diseases.
View Article and Find Full Text PDFbioRxiv
August 2025
Fogarty International Center, National Institutes of Health, Bethesda, Maryland, 20892, USA.
Background: In August 1995, necropsies on post-weaning piglets from the CA-CART farm in the province of Cartago, Costa Rica, revealed respiratory lesions, pleuritis, peritonitis, and arthritis. Skin lesions were also observed, progressing to scabs. A subsequent outbreak in 1996 prompted antibiotic administration.
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