Clinical efficacy and mechanism of and Chinese herbal compounds in treatment of peptic ulcer.

Peptic ulcer (PU) is characterized by inflammation, necrosis, and erosion of the gastrointestinal mucosa caused by various pathogenic factors, leading to ulcer formation. The stomach and duodenum are the most commonly affected sites. , a traditional Chinese medicinal herb, contains diverse chemical constituents and exhibits multiple pharmacological effects.

The Mkx- TGF-β pathway induced the development of the myodural bridge complex in SD rats.

Objective: The myodural bridge complex (MDBC) is a tendon-like structure highly conserved during vertebrate evolution, suggesting it plays an important physiological role. Substantial evidence indicates that the MDBC may contribute to cerebrospinal fluid (CSF) circulation by generating mechanical force. Studying its developmental process may offer new insights into CSF dynamics and lead to improved strategies for diagnosing and treating neurodegenerative diseases.

Mechanism of action of heat-clearing and detoxifying herbs in the treatment of erosive gastritis.

This article focuses on the clinical efficacy and mechanism of action of heat-clearing and detoxifying traditional Chinese medicines (TCMs) in the treatment of erosive gastritis, providing a reference for the treatment of this disease. In the clinical treatment of erosive gastritis, TCM combinations such as Qing Gastric San, Semixia Diarrheal Heart Soup, and single-flavored heat-clearing and detoxifying drugs such as dandelion and Huanglian have specific efficacies and effectively improve the patient's symptoms, including killing or inhibiting , reducing inflammatory reactions, protecting the gastric mucosa, inhibiting gastric acid secretion, regulating gastrointestinal hormones, and regulating immune function, playing therapeutic roles through multi-level and multi-target mechanisms. Thus, heat-clearing and detoxifying TCMs have broad application prospects in clinical practice for erosive gastritis.

[Evolutionary analysis of neuraminidase gene of A/H7N9 influenza virus].

In 2013, the World Health Organization reported the first case of human infection with a new influenza A (H7N9) virus in China. This has caused damage and panic within certain areas in China. Therefore, analysis of this virus with bioinformatics technology is very necessary.

Electronic structures and optical properties of organic dye sensitizer NKX derivatives for solar cells: a theoretical approach.

The photon to current conversion efficiency of dye-sensitized solar cells (DSCs) can be significantly affected by dye sensitizers. The design of novel dye sensitizers with good performance in DSCs depend on the dye's information about electronic structures and optical properties. Here, the geometries, electronic structures, as well as the dipole moments and polarizabilities of organic dye sensitizers C343 and 20 kinds of NKX derivatives were calculated using density functional theory (DFT), and the computations of the time dependent DFT with different functionals were performed to explore the electronic absorption properties.

Electronic structures and absorption properties of three kinds of ruthenium dye sensitizers containing bipyridine-pyrazolate for solar cells.

The geometries, electronic structures and the electronic absorption spectra of three kinds of ruthenium complexes, which contain tridentate bipyridine-pyrazolate ancillary ligands, were studied using density functional theory (DFT) and time-dependent DFT. The calculated results indicate that: (1) the strong conjugated effects are formed across the pyrazoalte-bipyridine groups; (2) the interfacial electron transfer between electrode and the dye sensitizers is an electron injection processes from the excited dyes to the conduction band of TiO2; (3) the absorption bands in visible region have a mixed character of metal-to-ligand charge transfer and ligand-to-ligand charge transfer, but the main character of absorption bands near UV region ascribe to π→π* transitions; (4) introducing pyrazolate and -NCS groups are favorable for intra-molecular charge transfer, and they are main chromophores that contribute to the sensitization of photon-to-current conversion processes, but introducing -Cl and the terminal group -CF3 are unfavorable to improve the dye performance in dye sensitized solar cells.