Effect of hypertension on clinical outcomes in ischemic colitis.

Background: The aim of this retrospective study was to uncover the effect of hypertension on ischemic colitis (IC).

Methods: Patients with IC were divided into two groups-hypertension (HP) and nonhypertension (NHP) groups-on the basis of their history of hypertension. Clinical features, biochemical indicators, endoscopic findings, abdominal pain relief time (APRT), hospital stay, operation rate, incidence of gangrenous IC, and 30-day mortality of IC were evaluated.

The Application of Three-dimensional Measurement and Grayscale Value Measurement Techniques in Lower Eyelid Blepharoplasty.

Background: Lower eyelid blepharoplasty addresses under-eye bags and tear troughs, but traditional evaluations lack objectivity. 3D imaging and grayscale analysis offer a novel, quantitative approach.

Objectives: To objectively assess blepharoplasty outcomes using 3D imaging and grayscale analysis, validating their effectiveness in capturing morphological and skin texture changes.

Bioactive oligopeptides and the application in skin regeneration and rejuvenation.

Oligopeptides, composed of 2-10 amino acid residues, are protein fragments with unique structural characteristics, including small molecular size, high biocompatibility, and modifiable functional groups. These features endow oligopeptides with excellent permeability, safety, and versatile biological activities, making them widely applicable in disease treatment, drug delivery, and skincare. In particular, oligopeptides have emerged as advanced ingredients in skincare, offering anti-aging, anti-wrinkle, and whitening effects by regulating key biological processes such as collagen synthesis, antioxidant defense, and melanin production.

Growth disturbances in bivalve shell: Implications for past and future intra-annual scale climate change.

Growth disturbances in bivalve shells are widely observed in both fossil and modern species, yet the conditions and mechanisms driving their formation remain unclear. Through controlled experiments on Mimachlamys nobilis, we demonstrate that abrupt intra-annual temperature fluctuations (≥5 °C) induce shell growth disturbances by altering the energy budget, diverting resources from shell growth to stress responses. Under ≥5 °C fluctuations (Groups C and D), 67 % of the individuals exhibited shell thinning, reduced growth rates, and formed growth disturbance lines (Groups C and D), whereas <5 °C fluctuations (Groups A and B) caused disturbances in only 12 % of the cases.

Application of Orbital Septal Fat Repositioning Combined With SVF-Gel Fillers in Lower Blepharoplasty.

Background: Lower blepharoplasty is a widely used cosmetic surgical procedure to improve under-eye bags and tear trough deformities, aiming to enhance facial aesthetics and achieve a more youthful appearance. The formation of these deformities is often associated with factors such as aging, skin laxity, and fat displacement. Traditional surgical methods include orbital septal fat repositioning and fat grafting, each with its own advantages and limitations.

Application of Wide, Adjustable External Traction Fixation in Conjunctival Approach Orbital Fat Reposition Surgery.

Background: The correction of tear trough deformities is a significant challenge. The aim of this study is to present a new technique of using wide, adjustable external traction fixation in conjunctival approach orbital fat reposition surgery.

Methods: This is a retrospective case series study conducted on 69 patients, aged 18 to 45 years, who underwent surgery for palpebral bags and tear trough deformities (TTD) between October 2022 and March 2024.

Analysis of the status and risk factors for Helicobacter pylori infection and drug resistance in the Lianyungang area, China.

Objective: Helicobacter pylori (H. pylori) has attracted much attention since its discovery. This bacterium has had a substantial impact on society, the economy, and public health.

Appendiceal orifice submucosal tumor: neuromuscular and vascular hamartoma.

A 61-year-old man was admitted to the gastroenterology department with a history of abdominal discomfort. He denied any past illness and family history of malignant tumors. Laboratory, electrocardiogram, and physical examination showed no obvious abnormality.

A New Method of Orbital Septal Fat Flap in Transconjunctival Approach.

Background: Orbital fat release is critical in blepharoplasty for correcting tear trough deformities, but traditional transconjunctival approaches often face limitations due to restricted fat volume and pedicle length. This study introduces an innovative technique by reconstructing the orbital fat flap, aiming to improve tear trough coverage and optimize Aesthet outcomes.

Methods: The technique is achieved by reconstructing the orbital fat flap.

The Application of Reverse Z-Plasty Design in Medial Canthal Skin Redundancy Reconstruction Surgery.

Purpose: To investigate the clinical outcomes of reverse Z-plasty in the reconstruction of epicanthal fold.

Methods: We conducted a retrospective analysis on clinical data from patients who underwent medial canthal skin redundancy reconstruction surgery from September 2019 to January 2023. The surgical procedure involved a preoperative design for the incision line, suborbicularis oculi dissection to create a muscle flap, and the use of a reverse Z-flap for the reconstruction of the lateral canthal fold.

Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study.

To evaluate the diagnostic accuracy of improved fluoroscopy-guided biopsies for indeterminate biliary strictures (IBDS). A multi-center retrospective study was performed. Patients with IBDS who underwent digital single-operator cholangioscopy (DSOC) and improved fluoroscopy-guided biopsies procedures were included.

Demystify esophageal submucosal tumor: angiomas.

A 51-year-old man presented to the gastroenterology department with a history of abdominal discomfort. Computed tomography was unremarkable. Upper gastrointestinal endoscopy showed a submucosal mass lesion at the esophagus, with a 36cm distance from the incisors.

Design strategies of Pt-based electrocatalysts and tolerance strategies in fuel cells: a review.

As highly efficient conversion devices, proton-exchange-membrane fuel cells (PEMFCs) can directly convert chemical energy to electrical energy with high efficiencies and lower or even zero emissions compared to combustion engines. However, the practical applications of PEMFCs have been seriously hindered by the intermediates (especially CO) poisoning of anodic Pt catalysts. Hence, how to improve the CO tolerance of the needed Pt catalysts and reveal their anti-CO poisoning mechanism are the key points to developing novel anti-toxic Pt-based electrocatalysts.

Novel elbow basket mechanical lithotripter for large common bile duct stone removal.

Background: Large common bile duct (CBD) stones often require lithotripsy. In this study, we aimed to introduce a novel device-elbow basket catheter for mechanical lithotripsy (ML) of CBD stones and assess the efficacy and safety of the novel device.

Methods: This was a retrospective study.

Modified Peroral Endoscopic Myotomy Technique for Type II Achalasia: A Multicenter Retrospective Study.

Aim: This retrospective study is aimed at evaluating the outcomes of a modified peroral endoscopic myotomy (POEM) technique in patients with type II achalasia.

Methods: We performed a modified POEM procedure, which involved a shorter (total myotomy length = 4 cm), full-thickness myotomy, on 31 patients with type II achalasia. Clinical success rates, technical success rates, pre- and postoperative esophageal manometry results, complications, and reflux-related adverse events were evaluated.

Knockdown of long non-coding RNA NEAT1 relieves inflammation of ulcerative colitis by regulating the miR-603/FGF9 pathway.

Ulcerative colitis (UC) is a significant threat to human life. Hence, there is an urgent requirement to understand the mechanism of UC progression and to develop novel therapeutic interventions for the treatment of UC. The present study aimed to evaluate the potential significance of long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) in the progression of UC.

Fishing line assisted endoscopic placement of multiple plastic biliary stents for unresectable malignant hilar biliary obstruction: a retrospective study.

Background And Aims: Stent migration is one of the most common complications during the placement of multiple plastic biliary stents (MPBS) under endoscopy. This study aims to evaluate the feasibility and efficiency of the fishing line assisted (FLA) method for preventing the complication.

Methods: Patients with unresectable malignant hilar biliary obstruction (MHBO) who undergone endoscopic placement of MPBS using the FLA or conventional method from May 2018 to April 2021 in our center were enrolled in the study.

Overexpression of circAtp9b in ulcerative colitis is induced by lipopolysaccharides and upregulates PTEN to promote the apoptosis of colonic epithelial cells.

It has been reported that knockdown of circular RNA (circ) ATPase class II type 9B (Atp9b) can reduce lipopolysaccharide (LPS)-induced inflammation, which plays a notable role in ulcerative colitis (UC). The present study aimed to explore the role of circAtp9b in UC. The expression levels of Atp9b and PTEN in the plasma of patients with UC (n=60) and healthy controls (n=60) were determined via reverse transcription-quantitative PCR.

Tissue sampling for biliary strictures using novel elbow biopsy forceps.

We aim to evaluate the safety and feasibility of novel elbow biopsy forceps with a prebent head for sampling biliary strictures in our institution. A total of 24 patients (15 males and 9 females) with biliary stricture who underwent biliary biopsy during endoscopic retrograde cholangiopancreatography (ERCP) using novel elbow biopsy forceps from June 2019 to August 2020 were retrospectively included. The novel biopsy forceps had a head angulation of 30 degrees and were able to cannulate the bile duct and approach the biliary strictures easily to obtain adequate samples.

A 3-DNA methylation signature as a novel prognostic biomarker in patients with sarcoma by bioinformatics analysis.

Background: Tumor-specific DNA methylation can potentially be a useful indicator in cancer diagnostics and monitoring. Sarcomas comprise a heterogeneous group of mesenchymal neoplasms which cause life-threatening tumors occurring throughout the body. Therefore, potential molecular detection and prognostic evaluation is very important for early diagnosis and treatment.

Knockdown of PLCB2 expression reduces melanoma cell viability and promotes melanoma cell apoptosis by altering Ras/Raf/MAPK signals.

Malignant melanoma has the highest malignancy rate among all skin cancer and is characterized by an insidious onset, high invasion and poor patient prognosis. Yet, the mechanisms involved remain unclear and warrant further investigation. Based on bioinformatic analysis, phospholipase C β2 (PLCB2) has been found to be correlated with melanoma growth.

Functional Genetic Single-Nucleotide Polymorphisms (SNPs) in Cyclin-Dependent Kinase Inhibitor 2A/B (CDKN2A/B) Locus Are Associated with Risk and Prognosis of Osteosarcoma in Chinese Populations.

BACKGROUND Cyclin-dependent kinase inhibitor 2A/B (CDKN2A/B) encodes several tumor suppressor proteins. Aberrant genetic alterations in CDKN2A/B were found in some malignancies, which were believed to be associated with tumor originating and progression. We hypothesized that CDKN2A/B genetic polymorphisms might be associated with the risk of poorer prognosis of osteosarcoma in Chinese populations.

Critical current measurements of high-temperature superconducting short samples at a wide range of temperatures and magnetic fields.

High-Temperature Superconductors (HTS) are potential materials for high-field magnets, low-loss transmission cables, and Superconducting Magnetic Energy Storage (SMES) due to their high upper critical magnetic field (H) and critical temperature (T). The critical current (I) of HTS, which is one of the most important parameters for superconductor application, depends strongly on the magnetic fields and temperatures. A new I measurement system that can carry out accurate I measurement for HTS short samples with various temperatures (4.

Evaluation of a new tension relief system for securing wound closure: A single-centre, Chinese cohort study.

Background: Wounds that have been closed under excessive tension, and skin defects that cannot be closed primarily, pose a daily challenge for the reconstructive surgeon.

Objective: To evaluate a new tension relief system (TRS) device for skin stretching and secure wound closure.

Methods: From September 2013 to March 2014, a consecutive series of 41 Chinese patients with 43 wounds were enrolled for application of 50 cycles of TRS therapy.