Hyalinizing trabecular tumor of the thyroid: A comprehensive review of clinicopathological features, diagnostic dilemmas, and emerging molecular insights.

Hyalinizing trabecular tumor (HTT), a rare thyroid neoplasm, is defined by its unique histopathological architecture and diagnostic complexity due to morphological mimicry of papillary thyroid carcinoma (PTC) and medullary thyroid carcinomas (MTC). This review consolidates contemporary insights into HTT's clinicopathological spectrum, diagnostic ambiguities, and molecular underpinnings. Epidemiologically, HTT predominantly affects middle-aged females, manifesting as circumscribed, asymptomatic nodules.

E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway.

E-cadherin (E-cad) is a crucial regulatory factor in rescue Epithelial-mesenchymal transition and is involved in the occurrence of various malignant tumor. However, the mechanisms by which E-cadherin regulates tumor metastasis in CRC remain unclear. We established sh-E-cad (silenced by short hairpin RNA) and rescue-E-cad (overexpressed by E-cad plasmid transfection) CRC cell lines to investigate the role of E-cad in CRC in vitro.

The Fungi-Bacteria Interaction Mechanism of Microbial Consortium During Efficient Lignin Degradation Based on Metabolomics Analysis.

Microbial consortium degradation technology can improve the degradation efficiency and adaptability through fungi-bacteria synergism, but the mechanism of the fungi-bacteria interaction is still unclear, making it difficult to optimize the degradation process. The microbial consortium J-6, with high lignin degradation efficiency and strong environmental adaptability, was obtained in our previous research. In this study, the fungi-bacteria interacting mechanism of the microbial consortium J-6 was inferred based on metabolomics technology.

Budd-Chiari syndrome associated with liver cirrhosis: A case report.

Background: Budd-Chiari syndrome (BCS) is a rare heterogeneous liver disease characterized by obstruction of the hepatic venous outflow tract. The incidence of BCS is so low that it is difficult to detect in general practice and difficult to include within the scope of routine diagnosis. The clinical manifestations of BCS are not specific; hence, BCS tends to be misdiagnosed.

[Anti-inflammatory effect, plasma effective components and therapeutic targets of Huanglian Jiedu Decoction on ulcerative colitis mice].

This paper was to investigate the effect of Huanglian Jiedu Decoction(HLJD) on ulcerative colitis(UC) in mice, and determine the effective components in plasma, and virtually screen its therapeutic target, and predict its mechanism. Sixty Balb/c mice were randomly divided into blank group, model group, mesalazine treatment group(0.3 g·kg~(-1)), and HLJD treatment groups(24.

Pharmacoproteomics reveals the mechanism of Chinese dragon's blood in regulating the RSK/TSC2/mTOR/ribosome pathway in alleviation of DSS-induced acute ulcerative colitis.

Ethnopharmacological Relevance: Chinese dragon's blood (CDB), a crude drug extracted from Dracaena cochinchinensis (Lour.) S.C.

Re-feeding evokes reproductive overcompensation of food-restricted Brandt's voles.

In natural conditions, animals have to cope with fluctuations of food resources. Animals having experienced prolonged decrease in feeding opportunities may increase their reproductive success when meeting abundant food. Though food restriction is well known to reduce reproductive success of animals, it is not clear whether re-feeding can restore or even overcompensate the reproductive success.

[Mechanism and clinical significance of anti-apoptotic gene bcl-2 expression in diffuse large B-cell lymphoma].

Objective: To evaluate the molecular mechanism and prognostication of bcl-2 protein expression in different subgroups of diffuse large B-cell lymphoma(DLBCL) in Guangxi Zhuang Autonomous Region, China.

Methods: Immunohistochemical stains for CD10, bcl-6, MUM-1, bcl-2 and NF-κB were performed in 214 cases of DLBCL. The Hans immunologic classification was applied to classify DLBCL into GCB and non-GCB subgroups.