Bone reporting and data system on CT (Bone-RADS-CT): a validation study by four readers on 328 cases from three local and two public databases.

Objective: To evaluate the reproducibility and effectiveness of the bone reporting and data system on CT (Bone-RADS-CT) for incidental solitary bone lesions in adults.

Materials And Methods: We retrospectively included 328 CT cases from three local and two public databases, respectively. All the cases were histopathologically or clinically confirmed bone lesions, "do not touch" lesions with typical appearance, and remained stable for at least 2 years.

Bone Reporting and Data System on MRI (Bone-RADS-MRI): a validation study by four readers on 275 cases from three local and two public databases.

Objective: To evaluate the reproducibility and effectiveness of the Bone Reporting and Data System on MRI (Bone-RADS-MRI) for incidental solitary bone lesions in adults.

Materials And Methods: We retrospectively included 275 MRI cases from three local and two public databases, respectively. All the cases were histopathologically or clinically confirmed bone lesions, or "do not touch" lesions with typical appearance and remained stable for at least two years.

Photon-Counting Detector CT Allows Abdominal Virtual Monoenergetic Imaging at Lower Kiloelectron Volt Level with Lower Noise Using Lower Radiation Dose: A Prospective Matched Study Compared to Energy-Integrating Detector CT.

Our study aimed to assess the image quality of lower kiloelectron volt (keV) level abdominal virtual monoenergetic imaging (VMI) with lower radiation dose on photon-counting detector computed tomography (PCD-CT), in comparison to energy-integrating detector computed tomography (EID-CT). We prospectively included three matched groups, each with 59 participants, to undergo contrast-enhanced abdominal CT scans using EID-CT with full-dose (EID_FD), PCD-CT with full-dose (PCD_FD), and PCD-CT with low-dose (PCD_LD) protocols, respectively. The data of portal-venous phase were reconstructed into VMI at 40, 50, 60, and 70 keV, respectively.

Assessment of Robustness of MRI Radiomic Features in the Abdomen: Impact of Deep Learning Reconstruction and Accelerated Acquisition.

The objective of this study is to investigate the impact of deep learning reconstruction and accelerated acquisition on reproducibility and variability of radiomic features in abdominal MRI. Seventeen volunteers were prospectively included to undergo abdominal MRI on a 3-T scanner for axial T2-weighted, axial T2-weighted fat-suppressed, and coronal T2-weighted sequences. Each sequence was scanned for four times using clinical reference acquisition with standard reconstruction, clinical reference acquisition with deep learning reconstruction, accelerated acquisition with standard reconstruction, and accelerated acquisition with deep learning reconstruction, respectively.

Multistep skyrmion phase transition driven by light-induced uniaxial strain.

Strain engineering in skyrmion-hosting multilayers holds promising potential for spintronic devices. However, conventional strain is below 0.5%, limiting exploration of unique properties under substantial strain.

Beyond Patient Safety: Exploring the Mechanism of How Organizational Support Influences Nurses' Safety Behavior in Pediatric Intensive Care Units.

Objective: To examine the relationships among safety culture perception, organizational support, and safety behavior in nurses working in the intensive care unit (ICU) of a pediatric hospital, as well as the underlying mechanisms.

Methods: We surveyed 133 ICU nurses using the Nurse Safety Behavior Scale, Nurse Culture Perception Questionnaire, and Organizational Support Questionnaire. Nurses completed questionnaires during designated breaks in their shifts.

Robustness of radiomics within photon-counting detector CT: impact of acquisition and reconstruction factors.

Objectives: To assess the impact of acquisition and reconstruction factors on the robustness of radiomics within photon-counting detector CT (PCD-CT).

Methods: A phantom with twenty-eight texture materials was scanned with different acquisition and reconstruction factors including reposition, scan mode (standard vs high-pitch), tube voltage (120 kVp vs 140 kVp), slice thickness (1.0 mm vs 0.

Comprehensive Review of Biological Functions and Therapeutic Potential of Perilla Seed Meal Proteins and Peptides.

This comprehensive review explores the biological functions of seed proteins and peptides, highlighting their significant potential for health and therapeutic applications. This review delves into the mechanisms through which perilla peptides combat oxidative stress and protect cells from oxidative damage, encompassing free radical scavenging, metal chelating, in vivo antioxidant, and cytoprotective activities. Perilla peptides exhibit robust anti-aging properties by activating the Nrf2 pathway, enhancing cellular antioxidant capacity, and supporting skin health through the promotion of keratinocyte growth, maintenance of collagen integrity, and reduction in senescent cells.

Overlooked and underpowered: a meta-research addressing sample size in radiomics prediction models for binary outcomes.

Objectives: To investigate how studies determine the sample size when developing radiomics prediction models for binary outcomes, and whether the sample size meets the estimates obtained by using established criteria.

Methods: We identified radiomics studies that were published from 01 January 2023 to 31 December 2023 in seven leading peer-reviewed radiological journals. We reviewed the sample size justification methods, and actual sample size used.

Node-RADS: a systematic review and meta-analysis of diagnostic performance, category-wise malignancy rates, and inter-observer reliability.

Objective: To perform a systematic review and meta-analysis to estimate diagnostic performance, category-wise malignancy rates, and inter-observer reliability of Node Reporting and Data System 1.0 (Node-RADS).

Methods: Five electronic databases were systematically searched for primary studies on the use of Node-RADS to report the possibility of cancer involvement of lymph nodes on CT and MRI from January 1, 2021, until April 15, 2024.

Ultra-High-Resolution Photon-Counting Detector CT Benefits Visualization of Abdominal Arteries: A Comparison to Standard-Reconstruction.

This study aimed to investigate the potential benefit of ultra-high-resolution (UHR) photon-counting detector CT (PCD-CT) angiography in visualization of abdominal arteries in comparison to standard-reconstruction (SR) images of virtual monoenergetic images (VMI) at low kiloelectron volt (keV). We prospectively included 47 and 47 participants to undergo contrast-enhanced abdominal CT scans within UHR mode on a PCD-CT system using full-dose (FD) and low-dose (LD) protocols, respectively. The data were reconstructed into six series of images: FD_UHR_Br48, FD_UHR_Bv56, FD_UHR_Bv60, FD_SR_Bv40, LD_UHR_Bv48, and LD_SR_Bv40.

Low-dose Ultra-high-resolution Photon-Counting Detector CT for Visceral Artery CT Angiography: A Preliminary Study.

Rationale And Objectives: To validate the image quality of low-dose ultra-high-resolution (UHR) scanning mode of photon-counting detector CT (PCD-CT) for visceral artery computed tomography angiography (CTA).

Material And Methods: We prospectively enrolled 57 patients each in the full dose (FD) and low-dose (LD) protocols, respectively, to undergo abdominal CT scans using the UHR mode on a PCD-CT system (NAEOTOM Alpha), between April 2023 and September 2023. Both the FD data and LD data were then reconstructed into two series of images: (a) 0.

The policies on the use of large language models in radiological journals are lacking: a meta-research study.

Objective: To evaluate whether and how the radiological journals present their policies on the use of large language models (LLMs), and identify the journal characteristic variables that are associated with the presence.

Methods: In this meta-research study, we screened Journals from the Radiology, Nuclear Medicine and Medical Imaging Category, 2022 Journal Citation Reports, excluding journals in non-English languages and relevant documents unavailable. We assessed their LLM use policies: (1) whether the policy is present; (2) whether the policy for the authors, the reviewers, and the editors is present; and (3) whether the policy asks the author to report the usage of LLMs, the name of LLMs, the section that used LLMs, the role of LLMs, the verification of LLMs, and the potential influence of LLMs.

Robustness of radiomics among photon-counting detector CT and dual-energy CT systems: a texture phantom study.

Objectives: To evaluate the robustness of radiomics features among photon-counting detector CT (PCD-CT) and dual-energy CT (DECT) systems.

Methods: A texture phantom consisting of twenty-eight materials was scanned with one PCD-CT and four DECT systems (dual-source, rapid kV-switching, dual-layer, and sequential scanning) at three dose levels twice. Thirty sets of virtual monochromatic images at 70 keV were reconstructed.

Deep learning image reconstruction for low-kiloelectron volt virtual monoenergetic images in abdominal dual-energy CT: medium strength provides higher lesion conspicuity.

Background: The best settings of deep learning image reconstruction (DLIR) algorithm for abdominal low-kiloelectron volt (keV) virtual monoenergetic imaging (VMI) have not been determined.

Purpose: To determine the optimal settings of the DLIR algorithm for abdominal low-keV VMI.

Material And Methods: The portal-venous phase computed tomography (CT) scans of 109 participants with 152 lesions were reconstructed into four image series: VMI at 50 keV using adaptive statistical iterative reconstruction (Asir-V) at 50% blending (AV-50); and VMI at 40 keV using AV-50 and DLIR at medium (DLIR-M) and high strength (DLIR-H).

Deep learning image reconstruction generates thinner slice iodine maps with improved image quality to increase diagnostic acceptance and lesion conspicuity: a prospective study on abdominal dual-energy CT.

Background: To assess the improvement of image quality and diagnostic acceptance of thinner slice iodine maps enabled by deep learning image reconstruction (DLIR) in abdominal dual-energy CT (DECT).

Methods: This study prospectively included 104 participants with 136 lesions. Four series of iodine maps were generated based on portal-venous scans of contrast-enhanced abdominal DECT: 5-mm and 1.

Complete genome sequence of sp. strain PD04, a pyridine-degrading bacterium under hypersaline condition.

We report the complete genome sequence of a pyridine-degrading sp. strain PD04 under 4% salinity environment, isolated from wastewater of coking plant. The genome is 6.

Discovery, optimization and biological activity evaluation of genipin derivatives as potential KRAS G12D inhibitors.

A series of genipin derivatives were designed and synthesized as potential inhibitors targeted KRAS G12D mutation. The majority of these compounds demonstrated potential antiproliferative effects against KRAS G12D mutant tumor cells (CT26 and A427). Notably, seven compounds exhibited the anticancer effects with IC values ranging from 7.

Factors associated with family decision-making self-efficacy among family members of patients with advanced cancer in mainland China.

Objectives: In Chinese culture, family members are the main decision maker on end-of-life (EoL) issues for patients with advanced cancer. Yet little is known about Chinese families' confidence in making EoL decisions and its associated factors. This study aims to investigate the status and associated factors of Chinese family members' confidence in making EoL decisions for patients with advanced cancer.

Just give the contrast? Appraisal of guidelines on intravenous iodinated contrast media use in patients with kidney disease.

Objective: To appraise the quality of guidelines on intravenous iodinated contrast media (ICM) use in patients with kidney disease, and to compare the recommendations among them.

Methods: We searched four literature databases, eight guideline libraries, and ten homepages of radiological societies to identify English and Chinese guidelines on intravenous ICM use in patients with kidney disease published between January 2018 and June 2023. The quality of the guidelines was assessed with the Scientific, Transparent, and Applicable Rankings (STAR) tool.

Bioinformatics and Experimental Study Revealed LINC00982/ miR-183-5p/ABCA8 Axis Suppresses LUAD Progression.

Background: Lung adenocarcinoma (LUAD) is a major health challenge worldwide with an undesirable prognosis. LINC00982 has been implicated as a tumor suppressor in diverse human cancers; however, its role in LUAD has not been fully characterized.

Methods: Expression level and prognostic value of LINC00982 were investigated in pan-cancer and lung cancer from The Cancer Genome Atlas (TCGA) project.

Design and optimization of ε-poly-l-lysine with specific functions for diverse applications.

ε-Poly-l-lysine (ε-PL) is a natural homo-poly(amino acid) which can be produced by microorganisms. With the advantages in broad-spectrum antimicrobial activity, biodegradability, and biocompatibility, ε-PL has been widely used as a preservative in the food industry. Different molecular architectures endow ε-PL and ε-PL-based materials with versatile applications.

Synthesis, biological activity evaluation and mechanism analysis of new ganglioside GM3 derivatives as potential agents for nervous functional recovery.

Neuronal regenerative ability is vital for the treatment of neurodegenerative diseases and neuronal injuries. Recent studies have revealed that Ganglioside GM3 and its derivatives may possess potential neuroprotective and neurite growth-promoting activities. Herein, six GM3 derivatives were synthesized and evaluated their potential neuroprotective effects and neurite outgrowth-promoting activities on a cellular model of Parkinson's disease and primary nerve cells.