A Fluorine-Free Organic/Inorganic Interphase for Highly Reversible Aqueous Zinc Batteries.

Construction of robust solid electrolyte interphases (SEIs) has proved effective in mitigating dendrite growth and side reactions of zinc (Zn) anodes in aqueous electrolytes. Fluorinated SEIs, in particular, have garnered significant attention due to their exceptional electrochemical stability and high Zn conductivity. However, the formation of such SEIs typically relies on the use of fluorine (F)-containing precursors, which inadvertently raise environmental and biological concerns because they show high resistance to degradation in natural environments.

HLS1 interacts with ATG8 to negatively regulate the ABS3-mediated plant senescence pathway.

In Arabidopsis, late endosome-localized ABNORMAL SHOOT 3 (ABS3) promotes senescence through a direct interaction with AUTOPHAGY8 (ATG8). However, the molecular mechanisms underlying the regulation of the ABS3-mediated senescence pathway are not well understood. Here, we report that HOOKLESS 1 (HLS1) acts as a negative regulator of plant senescence and the ABS3-mediated senescence pathway.

The kinesin motor POS3 and the microtubule polymerase MOR1 coordinate chromosome congression during mitosis in Arabidopsis.

Faithful chromosome segregation during mitosis is crucial for eukaryotic organisms. Centromere-associated protein-E (CENP-E), a kinetochore-localized kinesin motor, facilitates chromosome congression during mitosis in animals. However, it remains unclear whether plants rely on kinesins similar to CENP-E for chromosome alignment.

TAG-1 Regulates NRP1 in Schwann Cells and Participates in Regulating Nerve Regeneration in Rats with Sciatic Nerve Crush Injury.

Schwann cells (SCs) are necessary for peripheral nerve regeneration due to their plasticity and trophic supply after sciatic nerve injury (SNI). However, the multiple adaptations of SCs are still poorly understood. This study explored the effects of transient axonal glycoprotein type-1 (TAG-1) on cell migration and neuropilin1 (NRP1) expression in SCs and examined the impact of TAG-1 on nerve regeneration in rats with SNI.

The influence of palm fiber reinforcement on the cement content of vegetated concrete substrate under the condition of equal strength.

Vegetated concrete substrate (VCS) is a kind of ecological cemented soil, which has very wide application prospect in high and steep rock slope eco-protection. Cement is an important component of VCS, but it has high energy consumption and environmental pollution. Fiber reinforcement plays an positive role in improving the mechanical properties of soil, and its use as a substitute for cement content in VCS under the condition of equal strength is rarely investigated.

PRL1 interacts with and stabilizes RPA2A to regulate carbon deprivation-induced senescence in Arabidopsis.

Leaf senescence is a developmental program regulated by both endogenous and environmental cues. Abiotic stresses such as nutrient deprivation can induce premature leaf senescence, which profoundly impacts plant growth and crop yield. However, the molecular mechanisms underlying stress-induced senescence are not fully understood.

Increased GIRK channel activity prevents arrhythmia in mice with heart failure by enhancing ventricular repolarization.

Ventricular arrhythmia causing sudden cardiac death is the leading mode of death in patients with heart failure. Yet, the mechanisms that prevent ventricular arrhythmias in heart failure are not well characterized. Using a mouse model of heart failure created by transverse aorta constriction, we show that GIRK channel, an important regulator of cardiac action potentials, is constitutively active in failing ventricles in contrast to normal cells.

Effect of cell size distribution on mechanical properties of strawberry fruit tissue.

Strawberry fruit are high value, but also perishable products, because of their soft texture. Better insight on the strawberry mechanics are requested for understanding postharvest decay due to bruising. To gain data on the volumetric cell size distribution of strawberry tissue capturing the volume of 10 * 5 * 5 mm, fruit cells were suspended in 0.

Ultrasensitive lateral flow biosensor based on PtAu@CNTs nanocomposite catalytic chromogenic signal amplification strategy for the detection of nucleic acid.

A rapid and ultrasensitive lateral flow biosensor was developed, which based on gold and platinum nanoparticles-decorated carbon nanotubes (PtAu@CNTs) nanocomposite catalytic chromogenic signal amplification strategy for the detection of nucleic acid. Independent platinum and gold nanoparticles modified functional carbon nanotubes (PtAu@CNTs) were prepared by in-situ reduction. Sandwich-type hybridization reaction occurred between PtAu@CNTs-labeled DNA probe, target DNA and Biotin-modified DNA probes, which was captured on test zone of the strip.

Overexpression of lipocalin 2 in PBX1-deficient decidual NK cells promotes inflammation at the maternal-fetal interface.

Problem: Impairment of PBX1 expression in decidual natural killer (dNK) cells is associated with the pathogenesis of unexplained recurrent spontaneous abortion, which results in fetal growth restriction (FGR) by affecting the secretion of downstream growth factors. However, whether other mechanisms limit embryo growth in decidua containing PBX1-deficient natural killer (NK) cells is unknown.

Method Of Study: Pbx1 ; Ncr1 mice were employed to explore the underlying mechanisms by which PBX1 NK cells affect embryonic development.

Molecular dynamics simulation study of covalently bound hybrid coagulants (CBHyC): Molecular structure and coagulation mechanisms.

Covalently-bound organic silicate-aluminum hybrid coagulants (CBHyC) have been shown to efficiently remove low molecular weight organic contaminants from wastewater. However, the interaction dynamics and motivations during the coagulation of contaminant molecules by CBHyC are limited. In this study, a molecular dynamics (MD) simulation showed that CBHyC forms core-shell structure with the aliphatic carbon chains gather inside as a core and the hydrophilic quaternary ammonium-Si-Al complexes disperse outside as a shell.

ARF2-PIF5 interaction controls transcriptional reprogramming in the ABS3-mediated plant senescence pathway.

One of the hallmarks of plant senescence is the global transcriptional reprogramming coordinated by a plethora of transcription factors (TFs). However, mechanisms underlying the interactions between different TFs in modulating senescence remain obscure. Previously, we discovered that plant ABS3 subfamily MATE transporter genes regulate senescence and senescence-associated transcriptional changes.

The role of free fatty acid receptor pathways in a selective regulation of TRPA1 and TRPV1 by resolvins in primary sensory neurons.

Transient receptor potential ankyrin 1 and vanilloid 1 (TRPA1 and TRPV1, respectively) channels contribute to inflammatory and neuropathic pain, indicating that their pharmacological inhibition could be a novel strategy for treating painful diseases. However, the mechanisms of TRPA1/V1 channel modulation have been mostly characterized to be upregulation and sensitization via variety of exogenous stimuli, endogenous inflammatory mediators, and metabolites of oxidative stress. Here we used calcium imaging of dorsal root ganglion neurons to identify an inhibitor signaling pathway for TRPA1 and TRPV1 regulated by resolvins (RvD1 and RvE1), which are endogenous anti-inflammatory lipid mediators.

Modulation of I channel-PIP interaction by PRMT1 plays a critical role in the control of cardiac repolarization.

Recent studies have shown that protein arginine methyltransferase 1 (PRMT1) is highly expressed in the human heart, and loss of PRMT1 contributes to cardiac remodeling in the heart failure. However, the functional importance of PRMT1 in cardiac ion channels remains uncertain. The slow activating delayed rectifier K (I ) channel is a cardiac K channel composed of KCNQ1 and KCNE1 subunits and is a new therapeutic target for treating lethal arrhythmias in many cardiac pathologies, especially heart failure.

Textural thermo-mechanical properties of sweet cherry for postharvest damage analysis.

In this study, the textural thermo-mechanical properties of three sweet cherry varieties were systematically investigated by the puncture test of whole fruit, uniaxial tension of the exocarp, and uniaxial compression test of mesocarp. It was found that the puncture test can not only reflect the shear mechanics of the exocarp in vivo at the tissue level, but it can also characterize the resistance level of fruit to puncture damage at the macroscopic level, particularly when the puncture failure stress is used. The environmental temperature had negative and positive significant effects on the puncture failure stress and the puncture failure deformation of the sweet cherry (p < .

Riverside underwater noise pollution threaten porpoises and fish along the middle and lower reaches of the Yangtze River, China.

The Yangtze River exhibits a high biodiversity and plays an important role in global biodiversity conservation. As the world's busiest inland river in regard to shipping, little attention has been paid to underwater noise pollution. In 2017, the underwater noise level in 25 riverside locations along the middle and lower reaches of the Yangtze River mainly at night time were investigated by using passive acoustic monitoring method.

Correction to: Electroacupuncture Upregulated Ghrelin in Rats with Functional Dyspepsia via AMPK/TSC2/Rheb‑Mediated mTOR Inhibition.

The original version of the article is missing the grant information in Acknowledgments section. Corrected version of Acknowledgments is given below.

Recent progress on the organic and metal complex-based fluorescent probes for monitoring nitric oxide in living biological systems.

Nitric oxide (NO) is an important gaseous signaling molecule related to various human diseases. To investigate the biological functions of NO, many strategies have been developed for real-time monitoring the NO levels in biological systems. Among these strategies, fluorescent probes are considered to be one of the most efficient and applicable methods owing to their excellent sensitivity and selectivity, high spatiotemporal resolution, noninvasiveness, and experimental convenience.

Electroacupuncture Upregulated Ghrelin in Rats with Functional Dyspepsia via AMPK/TSC2/Rheb-Mediated mTOR Inhibition.

Background: Gastrointestinal motility disorder is an important pathological basis for functional dyspepsia (FD). Epigastric ache and discomfort are the main symptoms of FD, and ghrelin deficiency is closely related to the occurrence and development of FD. While electroacupuncture (EA) alleviated the symptoms of FD patients and improved their quality of life, there is a lack of sufficient mechanistic evidence to support these beneficial effects.

Solving the mystery of vanishing rivers in China.

A major controversy was sparked worldwide by a recent national water census claiming that the number of Chinese rivers with watersheds ≥100 km was less than half the previous estimate of 50 000 rivers, which also stimulates debates on the potential causes and consequences. Here, we estimated the number of rivers in terms of stream-segmentation characteristics described by Horton, Strahler and Shreve stream-order rules, as well as their mixed mode for named rivers recorded in the As a result, the number of 'vanishing rivers' has been found to be highly relevant to statistical specifications in addition to the erroneous inclusion of pseudo-rivers primarily generated in arid or frost-thaw areas. The modified Horton stream-order scheme reasonably depicts the configuration of complete natural streams from headwater to destination, while the Strahler largely projects the fragmentation of the named river networks associated with human aggregation to the hierarchical river systems.

Biotransformation of androst-4-ene-3,17-dione by three fungal species , and .

The microbial transformation of androst-4-ene-3,17-dione (4-AD; ) by three fungal species, involved , and , has been studied. The latter two fungi were studied for the first time on biotransformation of 4-AD. The main product obtained by was 17α-oxa-D-homo-androst-1,4-diene-3,17-dione (testolactone; IV), which can be used as an anticancer agent.

Long non‑coding RNA FER1L4 inhibits cell proliferation and metastasis through regulation of the PI3K/AKT signaling pathway in lung cancer cells.

Lung cancer is among the most common malignancies worldwide; however, the current understanding of its detailed mechanism remains limited. Long non‑coding RNAs (lncRNAs) were previously identified to serve significant roles in tumorigenesis. The present study aimed to investigate the role of a novel lncRNA, Fer‑1‑like family member 4 (FER1L4), in lung tumorigenesis.

Particulate air pollution and mortality in 38 of China's largest cities: time series analysis.

 To estimate the short term effect of particulate air pollution (particle diameter <10 μm, or PM) on mortality and explore the heterogeneity of particulate air pollution effects in major cities in China. Generalised linear models with different lag structures using time series data. 38 of the largest cities in 27 provinces of China (combined population >200 million).

Electro-oxidation of perfluorooctanoic acid by carbon nanotube sponge anode and the mechanism.

As an emerging persistent organic pollutant (POPs), perfluorooctanoic acid (PFOA) exists widely in natural environment. It is of particular significance to develop efficient techniques to remove low-concentration PFOA from the contaminated waters. In this work, we adopted a new material, carbon nanotube (CNT) sponge, as electrode to enhance electro-oxidation and achieve high removal efficiency of low-concentration (100μgL(-1)) PFOA from water.