Rapid advancements in autonomous driving technology have highlighted the challenges of ensuring vehicle safety and driving efficiency in complex dynamic traffic environments. Current approaches typically define potential risks as safety constraints for compliance and use them in trajectory planning. However, the risks predefined in these constraints are often fixed, reducing driving efficiency.
View Article and Find Full Text PDFMonolayer MoS is attractive for future photonics and optoelectronics for its direct-gap excitons with ultrahigh binding energies. However, the atomically thin structure is prone to nonradiative defects, challenging to scale for large-area production, and inherently limited in optical cross-section, all hindering technological integration. Stacking monolayers to increase the optical cross-section results in multilayers with diminished photoluminescence activity.
View Article and Find Full Text PDFTailoring magnetic ordering in solid-state materials is essential for emerging spintronics. However, substitutional lattice doping in magnetic semiconductors is often constrained by the low solubility of magnetic elements, limiting the maximum achievable doping concentration (for example, less than 5%) and ferromagnetic ordering temperature. The intercalation of magnetic elements in layered two-dimensional atomic crystals (2DACs) without breaking in-plane covalent bonds offers an alternative approach to incorporate a much higher concentration of magnetic atoms (for example, up to 50%) beyond the typical solubility limit.
View Article and Find Full Text PDFTransforming and repurposing plastic waste into valuable commodity chemical products is a sustainable strategy, which is beneficial for not only managing plastic waste but also fostering a circular plastic economy. Herein, we reported an electrocatalytic polyethylene terephthalate (PET) plastic waste upcycling to organonitrogen chemicals strategy over a MnO (MnO/CFP) catalyst. The MnO/CFP catalyst is capable of mildly oxidizing PET plastic-waste-derived ethylene glycol (EG) to electrophilic carbon intermediates under near-neutral conditions, in which the in situ formed carbon intermediates were stabilized and further attacked by nitrogenous nucleophiles, leading to the successful formation of amides.
View Article and Find Full Text PDFProton exchange membrane fuel cells feature considerable scalability advantages over lithium-ion batteries for heavy-duty-vehicle applications. The different driving behaviours and operating conditions of heavy-duty vehicles pose challenging requirements, particularly on fuel cell lifetime and efficiency. Here we report the design of a graphene-nanopocket-protected, pore-confined and electrochemically accessible Pt nanocatalyst supported on Ketjenblack carbon for heavy-duty-vehicle applications.
View Article and Find Full Text PDFFood Sci Biotechnol
February 2025
Unlabelled: Growing evidence suggests that dietary herbs can prevent stroke by regulating the composition and structure of gut microbiota. The components of dietary herbs can also be metabolized or converted into bioactive molecules for treating stroke by gut microbiota, and exert therapeutic effects by inhibiting inflammation, oxidative stress, apoptosis, and other processes caused by stroke. A deep understanding of the mechanism of gut microbiota-mediated dietary herbal intervention in stroke is of great significance for the treatment and drug screening of stroke diseases.
View Article and Find Full Text PDFJ Nanobiotechnology
February 2025
There are abundant natural products resources and extensive clinical use experience in China. However, the active components of natural products generally have problems such as poor water solubility and low bioavailability, which limit their druggability. Carrier-free nanoparticles, such as nanocrystals, self-assembled nanoparticles, and extracellular vesicles derived from both animal and plant sources, have great application potential in improving the safety and efficacy of drugs due to their simple and flexible preparation methods, high drug loading capacity and delivery efficiency, as well as long half-life in blood circulation.
View Article and Find Full Text PDFToxicol Mech Methods
June 2025
Current studies have clearly shown that aristolochic acid (AA) exposure can induce a variety of diseases, such as kidney disease, liver cancer, and urinary tract cancer (UTC). However, no studies have systematically analyzed and integrated these results. Therefore, we aimed to elucidate the association between AA exposure and the risk of safety outcomes for AA-related overall disease and different types of disease it causes.
View Article and Find Full Text PDFPostconsumer plastics are generally perceived as valueless with only a small portion of plastic waste being closed-loop recycled into similar products while most of them are discarded in landfills. Depositing plastic waste in landfills not only harms the environment but also signifies a substantial economic loss. Alternatively, constructing value-added chemical feedstocks via mining the waste-derived intermediate species as a carbon (C) source under mild electrochemical conditions is a sustainable strategy to realize the circular economy.
View Article and Find Full Text PDFUpcycling plastic wastes into value-added chemicals is a promising approach to put end-of-life plastic wastes back into their ecocycle. As one of the polyesters that is used daily, polyethylene terephthalate (PET) plastic waste is employed here as the model substrate. Herein, a nickel (Ni)-based catalyst was prepared via electrochemically depositing copper (Cu) species on Ni foam (NiCu/NF).
View Article and Find Full Text PDFBackground: Mycotoxins have been reported to be present in medicinal plants. With the growing usage of medicinal plants, contamination of mycotoxins has emerged as one of the biggest threats to global food hygiene and ecological environment, posing a severe threat to human health.
Purpose: This study aimed to determine the mycotoxin prevalence and levels in medicinal plants and conduct a risk assessment by conducting a systematic review and meta-analysis.
Ulcerative colitis (UC) represents an inflammatory disease characterized by fluctuations in severity, posing substantial challenges in treatment. The gut microbiota plays a pivotal role in the pathogenesis of UC. This study sought to identify drugs specifically targeting the gut microbiota to mitigate UC.
View Article and Find Full Text PDFArch Med Res
January 2024
ACS Mater Lett
November 2023
Photocatalytic plastic waste upcycling into value-added feedstock is a promising way to mitigate the environmental issues caused by the nondegradable nature of plastic waste. Here, we developed a MoS/g-CN photocatalyst that can efficiently upcycle poly(ethylene terephthalate) (PET) into valuable organic chemicals. Interestingly, the conversion mechanism is concentration-dependent.
View Article and Find Full Text PDFJ Chromatogr B Analyt Technol Biomed Life Sci
September 2023
Fructus Psoraleae (FP), one of the important traditional Chinese medicines, is widely used in clinic and has been reported to be hepatotoxic. However, there is no report on the mechanism of FP-induced hepatotoxicity based on the theory of You Gu Wu Yun. In this study, plasma samples of rats with different kidney deficiency syndromes were investigated using a lipidomics approach based on UPLC/Q-TOF-MS technique.
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