Microbial electrotrophs-driven molecular transformations of dissolved organic matter in paddy soil.

Microbial electrotrophs are key players in biogeochemical cycles, but the impact of electrotrophic communities on the diverse chemical composition and properties of dissolved organic matter (DOM) molecules in paddy soils has not been comprehensively explored. Herein, we investigated the response of DOM molecules in paddy soil-based microcosms to electrotrophic communities using microbial electrosynthesis systems (MESs), high-resolution mass spectrometry, and genome-centric metagenomics techniques. Compared to the open-circuit control, the closed-circuit system exhibited a 2.

Piezoelectric properties improvement in soft membrane with wet-spinning prepared barium titanate/polyvinylidenefluoride composites fiber.

Piezoelectric composite materials have demonstrated significant potential for developing high-performance wearable sensors. However, optimizing the piezoelectric output performance in polymer-based devices remains challenging due to the suboptimal synergy between the piezoelectric reinforcement phase and substrate materials. Moreover, the instability of response signals further hampers the sensor's practical utility.

Development of stable and sensitive strip biosensors for the rapid detection of organophosphates and aflatoxin B1 in agricultural samples.

In this study, we present a facile and efficient method for fabricating silk fibroin hydrogel films encapsulating the acetylcholinesterase enzyme (AChE) and pH test strips (biosensor strips) for detecting organophosphorus pesticides (OPs) and aflatoxin B1 (AFB1). These biosensor strips possess several unique properties: flexibility, time efficiency, and high stability. Upon exposure to OPs or AFB1, AChE activity is inhibited, leading to a discernible color change on the pH test strip, enabling rapid and sensitive visual detection of these contaminants.

A Ratiometric Fluorescence Nano pH Biosensor for Live-Cell Imaging Using Cerasome.

The development of a robust and biocompatible pH-sensing platform is critical for monitoring intracellular processes and diagnosing diseases. Here, we present a smart ultrastable ratiometric fluorescence nano pH sensor based on silica-coated liposome nanoparticles (cerasome, 138.4 nm).

Universal cell membrane camouflaged nano-prodrugs with right-side-out orientation adapting for positive pathological vascular remodeling in atherosclerosis.

A right-side-out orientated self-assembly of cell membrane-camouflaged nanotherapeutics is crucial for ensuring their biological functionality inherited from the source cells. In this study, a universal and spontaneous right-side-out coupling-driven ROS-responsive nanotherapeutic approach, based on the intrinsic affinity between phosphatidylserine (PS) on the inner leaflet and PS-targeted peptide modified nanoparticles, has been developed to target foam cells in atherosclerotic plaques. Considering the increased osteopontin (OPN) secretion from foam cells in plaques, a bioengineered cell membrane (OEM) with an overexpression of integrin α9β1 is integrated with ROS-cleavable prodrugs, OEM-coated ETBNPs (OEM-ETBNPs), to enhance targeted drug delivery and on-demand drug release in the local lesion of atherosclerosis.

DPA-2: a large atomic model as a multi-task learner.

The rapid advancements in artificial intelligence (AI) are catalyzing transformative changes in atomic modeling, simulation, and design. AI-driven potential energy models have demonstrated the capability to conduct large-scale, long-duration simulations with the accuracy of electronic structure methods. However, the model generation process remains a bottleneck for large-scale applications.

Facet Dependence of Biosynthesis of Vivianite from Iron Oxides by .

Vivianite plays an important role in alleviating the phosphorus crisis and phosphorus pollution. The dissimilatory iron reduction has been found to trigger the biosynthesis of vivianite in soil environments, but the mechanism behind this remains largely unexplored. Herein, by regulating the crystal surfaces of iron oxides, we explored the influence of different crystal surface structures on the synthesis of vivianite driven by microbial dissimilatory iron reduction.

Complete pentachlorophenol biodegradation in a dual-working electrode bioelectrochemical system: Performance and functional microorganism identification.

Bioelectrochemical system (BES) can effectively promote the reductive dechlorination of chlorophenols (CPs). However, the complete degradation of CPs with sequential dechlorination and mineralization processes has rarely achieved from the BES. Here, a dual-working electrode BES was constructed and applied for the complete degradation of pentachlorophenol (PCP).

A data-driven approach for understanding the structure dependence of redox activity in humic substances.

Humic substances (HS) can facilitate electron transfer during biogeochemical processes due to their redox properties, but the structure-redox activity relationships are still difficult to describe and poorly understood. Herein, the linear (Partial Least Squares regressions; PLS) and nonlinear (artificial neural network; ANN) models were applied to monitor the structure dependence of HS redox activities in terms of electron accepting (EAC), electron donating (EDC) and overall electron transfer capacities (ETC) using its physicochemical features as input variables. The PLS model exhibited a moderate ability with R values of 0.

Bioaccessibility of arsenic, lead, and cadmium in contaminated mining/smelting soils: Assessment, modeling, and application for soil environment criteria derivation.

Soil environment criteria (SEC) are commonly derived from the total concentration of pollutants in soils, resulting in overly stringent values. Herein, we examined the feasibility of deriving the SEC by using the bioaccessibility of pollutants. In this regard, soil samples from 33 locations at 12 mining/smelting sites in China were collected and examined in terms of soil properties, chemical fraction distributions, and bioaccessibilities of cadmium (Cd), lead (Pb), and arsenic (As).

ORFV infection enhances CXCL16 secretion and causes oncolysis of lung cancer cells through immunogenic apoptosis.

Oncolytic viruses have been emerging as a promising therapeutic option for cancer patients, including lung cancer. Orf virus (ORFV), a DNA parapoxvirus, can infect its natural ungulate hosts and transmit into humans. Moreover, the ORFV has advantages of low toxicity, high targeted, self-amplification and can induce potent Th1-like immunity.

Structure and core taxa of bacterial communities involved in extracellular electron transfer in paddy soils across China.

Microbial communities with extracellular electron transfer (EET) activity are capable of driving geochemical changes and cycles, but a comprehensive understanding of the key microbiota responsible for EET in complex soil matrices is still lacking. Herein, the EET activities, in terms of maximum current density (j) and accumulated charge output (C), of 41 paddy soils across China were evaluated from the exoelectrogenic properties with a conventional bioelectrochemical system (BES). The j with a range of 8.

Unveiling metabolic characteristics of an uncultured Gammaproteobacterium responsible for in situ PAH biodegradation in petroleum polluted soil.

Exploring the metabolic characteristics of indigenous PAH degraders is critical to understanding the PAH bioremediation mechanism in the natural environment. While stable-isotopic probing (SIP) is a viable method to identify functional microorganisms in complex environments, the metabolic characteristics of uncultured degraders are still elusive. Here, we investigated the naphthalene (NAP) biodegradation of petroleum polluted soils by combining SIP, amplicon sequencing and metagenome binning.

Stimulation of phenanthrene and biphenyl degradation by biochar-conducted long distance electron transfer in soil bioelectrochemical systems.

The bioelectrochemical degradation of organic pollutants has attracted considerable attention owing to its remarkable sustainability and low cost. However, the application of bioelectrochemical system (BES) for the degradation of pollutants in soils is hindered by limitations in the effective distance in the soil matrix. In this study, a biochar-amended BES was constructed to evaluate the degradation of organic pollutants.

Confronting the threat of SARS-CoV-2: Realities, challenges and therapeutic strategies (Review).

The novel coronavirus (SARS-CoV-2) appeared in2019 in Wuhan, China, and rapidly developed into a global pandemic. The disease has affected not only health care systems and economies worldwide but has also changed the lifestyles and habits of the majority of the world's population. Among the potential targets for SARS-CoV-2 therapy, the viral spike glycoprotein has been studied most intensely, due to its key role in mediating viral entry into target cells and inducing a protective antibody response in infected individuals.

Enhanced degradation of triphenyl phosphate (TPHP) in bioelectrochemical systems: Kinetics, pathway and degradation mechanisms.

Triphenyl phosphate (TPHP) is one of the major organophosphate esters (OPEs) with increasing consumption. Considering its largely distribution and high toxicity in aquatic environment, it is important to explore an efficient treatment for TPHP. This study aimed to investigate the accelerated degradation of TPHP in a three-electrode single chamber bioelectrochemical system (BES).

Solar Photothermal Electrodes for Highly Efficient Microbial Energy Harvesting at Low Ambient Temperatures.

Temperature is an important parameter for the performance of bioelectrochemical systems (BESs). Energy-intensive bulk water heating has been usually employed to maintain a desired temperature for the BESs. This study concerns a proof-of-concept of a light-to-heat photothermal electrode for solar heating of a local electroactive biofilm in a BES for efficient microbial energy harvesting at low temperatures as a replacement for bulk water heating approaches.

The Contrasting Effects of Alum-Treated Chicken Manures and KH2PO4 on Phosphorus Behavior in Soils.

Alum [KAl(SO)⋅12HO] is often added to chicken manure to limit P solubility after land application. This is generally ascribed to the formation of Al-PO complexes. However, Al-PO complex formation could be affected by the matrix of chicken manure, which varies with animal diet.