sp. nov. and sp. nov., two novel actinobacteria isolated from rhizosphere soil with broad-spectrum antifungal activity.

Two actinobacterial strains, designated NEAU-383 and NEAU-Y11, exhibiting antifungal activity, were isolated from the rhizosphere soil of plants in Harbin, Heilongjiang Province, and Guangzhou, Guangdong Province, respectively. Both strains formed short, wrinkled, spiral spore chains on aerial hyphae. Phylogenetic analysis based on 16S rRNA gene sequences revealed that strains NEAU-383 and NEAU-Y11 were most closely related to HM 35, NRRL B-5491 and CA1R205.

Antifungal Activity and Potential Mechanisms of Two Bafilomycin Analogues Isolated from sp. NEAU-Y11 against .

Cucumber anthracnose, caused by , severely affects the cucumber yield and quality. In this study, two active compounds, bafilomycin C and JBIR-100, were isolated from strain NEAU-Y11 and exhibited strong antifungal activity against , with EC values of 0.0491 and 0.

Salt-alkali-tolerant growth-promoting Streptomyces sp. Jrh8-9 enhances alfalfa growth and resilience under saline-alkali stress through integrated modulation of photosynthesis, antioxidant defense, and hormone signaling.

Streptomyces is a group of plant growth-promoting microorganisms with considerable potential for enhancing plant tolerance to environmental stress. However, the mechanisms by which Streptomyces strains induce systemic tolerance to saline-alkaline stress remain unclear. Here, we evaluated the properties of Streptomyces sp.

Discovery of (+)-Methyl Nonactate as a Potential Fungicide against Gummy Stem Blight.

Gummy stem blight (GSB), which is caused by , threatens pumpkin yields and agriculture. Effective, safe antifungal agents are urgently needed. In this study, fermentation broth supernatant of sp.

Enhancing cellulose and hemicellulose degradation in wheat straw composting by inoculation with : key factors and microbial community dynamics.

Actinobacteria are widely used in aerobic composting of straw waste because of their good degradation effect on lignocellulose. However, there are few studies on the degradation effect of on straw. In this study, six laboratory-scale treatments were conducted: corn straw composting with inoculation (CSI), rice straw composting with inoculation (RSI), and wheat straw composting with inoculation (WSI).

Bidirectional Decoupled Distillation for Heterogeneous Federated Learning.

Federated learning enables multiple devices to collaboratively train a high-performance model on the central server while keeping their data on the devices themselves. However, due to the significant variability in data distribution across devices, the aggregated global model's optimization direction may differ from that of the local models, making the clients lose their personality. To address this challenge, we propose a Bidirectional Decoupled Distillation For Heterogeneous Federated Learning (BDD-HFL) approach, which incorporates an additional private model within each local client.

Risk factors and incidence of central venous access device-related thrombosis in hospitalized children: a systematic review and meta-analysis.

Background: The risk factors for central venous access device-related thrombosis (CRT) in children are not fully understood. We used evidence-based medicine to find the risk factors for CRT by pooling current studies reporting risk factors of CRT, aiming to guide clinical diagnosis and treatment.

Methods: A systematic search of PubMed, Web of Science, Embase, Cochrane Library, Scopus, CNKI, Sinomed, and Wanfang databases was conducted.

sp. nov., a novel indole-producing and cellulose-degrading bacterium isolated from soil.

A Gram-stain-negative, rod-shaped, indole-producing, and cellulose-degrading bacterial strain, designated NEAU-G-C5, was isolated from soil collected from a forest in Dali city, Yunnan province, south China. 16S rRNA gene sequence analysis showed that strain NEAU-G-C5 was assigned to the genus and showed high sequence similarities to 12-OD1 (98.32 %) and 6 NM-7 (98.

Risk factors and incidence of postoperative delirium after cardiac surgery in children: a systematic review and meta-analysis.

Delirium, a form of acute cerebral dysfunction, is a common complication of postoperative cardiac surgery in children. It is strongly associated with adverse outcomes, including prolonged hospitalization, increased mortality, and cognitive dysfunction. This study aimed to identify risk factors and incidence of delirium after cardiac surgery in children to facilitate early identification of delirium risk and provide a reference for the implementation of effective prevention and management.

Predictors of extubation failure in newborns: a systematic review and meta-analysis.

Extubation failure (EF) is a significant concern in mechanically ventilated newborns, and predicting its occurrence is an ongoing area of research. To investigate the predictors of EF in newborns undergoing planned extubation, we conducted a systematic review and meta-analysis. A systematic literature search was conducted in PubMed, Web of Science, Embase, and Cochrane Library for studies published in English from the inception of each database to March 2023.

Breastfeeding needs of mothers of preterm infants in China: a qualitative study informed by the behaviour change wheel.

Background: Although breastfeeding is strongly recommended, the breastfeeding rate of preterm infants in China remains significantly low. In addition to the global structural challenges to breastfeeding and the physiological immaturity of preterm infants, Chinese mothers of preterm infants face unique challenges of maternal-infant separation after birth. Moreover, little is known about Chinese mothers' specific needs in coping with the difficulties posed by these challenges.

Risk factors for length of NICU stay of newborns: A systematic review.

Background: The improvement in survival of preterm infants is accompanied by an increase in neonatal intensive care unit (NICU) admissions. Prolonged length of stay in the NICU (LOS-NICU) increases the incidence of neonatal complications and even mortality and places a significant economic burden on families and strain on healthcare systems. This review aims to identify risk factors influencing LOS-NICU of newborns and to provide a basis for interventions to shorten LOS-NICU and avoid prolonged LOS-NICU.

Description of a new strain of and reclassification of as a later heterotypic synonym of .

A novel actinomycete, designated strain NEAU-YY374, was isolated from root of wheat and a polyphasic taxonomic study was carried out. 16S rRNA gene sequence analysis indicated that strain NEAU-YY374 was closely related to NEAU-Jh2-17 (99.3 %) and 12A09 (98.

Sarubicinols A-C, Cytotoxic Benzoxazoles from a .

A chemical investigation of sp. Hu186 afforded two known quinone antibiotics, sarubicin A () and sarubicin B (), together with three unusual variants, sarubicinols A-C (-), and two new 1,4-naphthoquinone metabolites, sarubicin B () and sarubicin B (). Compounds - possess a rare 2-oxabicyclo [2.

Two new cyclopentenone metabolites from sp. HU119.

Two previously undescribed cyclopentenone metabolites, ()-2-(3-acetylamino-2-methyl)propyl-3-butyl-2-cyclopenten-1-one () and ()-2-(3-acetylamino-2-ethyl)propyl-3-butyl-2-cyclopenten-1-one (), were isolated from the fermentation broth of the strain sp. HU119. The structures of and were determined by the comprehensive spectroscopic analysis, including 1 D, 2 D NMR, MS spectral analysis and the comparison with data from the literature.

sp. nov., an indole acetic acid-producing actinobacterium isolated from cow dung.

A novel growth-promoting and indole acetic acid-producing strain, designated NEAU-LLB, was isolated from cow dung collected from Shangzhi, Heilongjiang Province, PR China. Cells of strain NEAU-LLB were Gram-stain-positive, non-motile, aerobic and non-spore-forming. Phylogenetic analysis based on 16S rRNA gene sequence indicated that strain NEAU-LLB belonged to the genus .

A new -class milbemycin derivative from a mutant of genetically engineered strain AVE-H39.

A new -class milbemycin, 13hydroxy milbemycin (), was isolated from the fermentation broth of a mutant of genetically engineered strain AVE-H39. Its structure and absolute configuration were elucidated by extensive spectroscopic methods and confirmed by single crystal X-ray diffraction.

Taxonomic Characterization and Secondary Metabolite Analysis of NEAU-wh3-1: An Strain with Antitumor and Antibacterial Activity.

Cancer is a serious threat to human health. With the increasing resistance to known drugs, it is still urgent to find new drugs or pro-drugs with anti-tumor effects. Natural products produced by microorganisms have played an important role in the history of drug discovery, particularly in the anticancer and anti-infective areas.