Functional and Visual Outcomes of Orbital Floor Fracture Repair Using Titanium Mesh: A Retrospective Cross-Sectional Study.

Objective This retrospective study aims to evaluate the functional and visual outcomes of patients undergoing orbital floor fracture repair using titanium mesh implants. Methods Medical records of patients treated over four years for isolated or combined orbital floor fractures using titanium mesh were reviewed. Clinical outcomes assessed included diplopia, enophthalmos, ocular motility, and visual acuity, both pre- and postoperatively.

Effect of Dietary Supplementation of Biochars on Growth Performance, Bone Mineralization, Footpad Health, Lymphoid Organs Weight, Antibody Titers of Newcastle Disease and Infectious Bronchitis Disease in Broiler Chicks.

This study evaluated the effect of biochars on growth performance, nutrient digestibility, carcass yield, bone mineralization, litter quality and footpad lesions in broilers. Eight hundred day-old chicks were randomly divided into four treatments, 10 replicates per treatment (20 birds/replicate) for 35 days. Treatments were basal diet (control), a control diet with corncob (CC) biochar (1%), a control diet with wheat straw (WS) biochar (1%) and a control diet with sugarcane bagasse (SCB) biochar (1%).

Yeast β-glucan ameliorated Salmonella-induced gut impairment in broiler chickens by modulating gut microbiome.

Yeast β-glucan (YG) was reported to control Salmonella infection in poultry. Gut microbiota plays an important role in regulating immune functions and intestinal health. However, it is still unclear whether YG protects chickens from Salmonella infection by regulating gut microbiota.

Sprayable ciprofloxacin loaded chitosan nanospheres-based topical formulation for eliminating multidrug-resistant bacteria and accelerating infected wound healing.

Multidrug-resistant (MDR) bacteria represent a formidable global health crisis with a substantial risk of prolonged infections due to the diminishing efficacy of traditional antibiotic therapies against these resilient pathogens. A dual strategy offering rapid inactivation of MDR bacteria and reduction in wound area could effectively promote wound healing. In this work, we developed a sprayable topical formulation by integrating a biocompatible biopolymer chitosan with a chemotherapeutic drug ciprofloxacin.

Development of NiCoO/rGO Nanocomposites for High Performance Supercapacitors.

Transition metal oxide nanocomposites featuring diverse structures have garnered significant attention in the realm of supercapacitors. This interest is attributed to their cost-effectiveness, high surface area, rapid transport of ions and electrons, and the ability to deliver high specific capacitance. In this work, sea-urchin shaped NiCoO reduced graphene oxide (NCO/rGO) nanocomposites were synthesized via facile hydrothermal route.

Effects of partial soybean meal replacement with sunflower meal and non-starch polysaccharide degrading enzymes supplementation on broiler growth performance, nutrient digestibility, and gut morphology.

Background And Aim: Soybean meal (SBM) is the primary protein source in broiler diets; however, its high cost and import dependency necessitate alternative protein sources. Sunflower meal (SFM) is a viable alternative but contains high fiber and non-starch polysaccharides (NSPs), which can impair nutrient utilization. This study evaluated the effects of partially replacing SBM with SFM, with or without NSP degrading enzymes (NSPase) enzyme supplementation, on growth performance, nutrient digestibility, digesta viscosity, and gut morphology in broilers.

A natural gene on-off system confers field thermotolerance for grain quality and yield in rice.

Rising global temperatures threaten crop grain quality and yield; however, how temperature regulates grain quality and how to achieve synergistic thermotolerance for both quality and yield remain unknown. Here, we identified a rice major locus, QT12, which negatively controls grain-quality field thermotolerance by disrupting endosperm storage substance homeostasis through over-activating unfolded protein response (UPR). Natural variations in QT12 and an NF-Y complex form a natural gene on-off system to modulate QT12 expression and thermotolerance.

The role of Seladelpar in primary biliary cholangitis: a systematic review and meta-analysis.

Introduction: Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease characterized by progressive bile duct destruction, leading to cholestasis and, if untreated, liver failure. Although ursodeoxycholic acid (UDCA) remains the first-line treatment, many patients exhibit an inadequate response, necessitating alternative therapeutic options. Seladelpar, a peroxisome proliferator-activated receptor delta (PPAR-δ) agonist, has emerged as a promising alternative due to its anti-inflammatory and anti-fibrotic properties.

Physico-Chemical Characteristics, Antioxidant Activities, and ACE Inhibitory Potential of Pakistani Dahi Supplemented With Date Fruit Paste.

Dahi as well as date fruits are considered very important in our diet due to the presence of nutritional and medicinal properties. The objective of this study was to evaluate the antioxidant potential and angiotensin-I-converting enzyme (ACE) inhibitory activity of date paste added to indigenous dahi during storage (0-8 days, 5°C). The prepared dahi was also evaluated for its physico-chemical characteristics and microbiological and sensorial quality during the storage period.

Effect of Ideal Amino Acid Ratio of Arginine to Lysine on Intake, Nutrient Digestibility, Growth Performance, Antibody Titers of Newcastle Disease and Infectious Bronchitis Disease, and Carcass Characteristics of Broilers.

This study aimed to assess the effects of different arginine (Arg) to lysine (Lys) ratios on feed intake, nutrient digestibility, growth performance, carcass characteristics, and antibody titers of Newcastle disease (ND) and infectious bronchitis (IB) disease in broilers during 35 days of trial. For this purpose, a total of 816 day-old broiler birds having an average weight of 38 ± 3 g were divided into six dietary treatments in such a way that each treatment had eight replicates and each replicate had 17 birds. The treatments were 0.

Yeast cell wall polysaccharides accelerate yet in-feed antibiotic delays intestinal development and maturation via modulating gut microbiome in chickens.

Background: It is important to promote intestinal development and maturation of chicks for feed digestion and utilization, intestinal health, and disease resistance. This study aimed to investigate the effects of dietary yeast cell wall polysaccharides (YCWP) addition on intestinal development and maturation of chickens and its potential action mechanism.

Methods: 180 one-day-old male Arbor Acres broilers were randomly assigned to three groups containing control (basal diets without any antibiotics or anticoccidial drug), bacitracin methylene disalicylate (BMD)-treated group (50 mg/kg) and YCWP-supplemented group (100 mg/kg).

Multiclass Synthetic Accessibility Prediction.

Evaluating synthetic accessibility of molecules is an integral component of the drug discovery process. While the application of machine learning models to predict whether small molecules are easy or hard to synthesize has gained attention recently, predetermined thresholds and data set imbalances present challenges for these binary classification approaches. In this study, we introduce a novel multiclass fold-ensembled classification approach to predict the minimum number of steps needed to synthesize a small molecule.

Particle size of wheat straw from genetically improved wheat affects the production performance and feeding behavior of Sahiwal cows.

The current study was designed to evaluate the effect of particle size (PS) and inclusion level of wheat straw (WS) obtained from genetically improved wheat on the performance and feeding behavior of Sahiwal cows. Twelve multiparous, mid-lactating Sahiwal cows (DIM 135 ± 25, mean ± SD; 12.8 ± 1.

Effects of drinking water supplemented with essential oils and organic acids mixtures on growth performance and intestinal health of broilers challenged with necrotic enteritis.

It is urgent to develop effective antibiotic alternatives for the control of subclinical necrotic enteritis (NE) in chickens after in-feed antibiotics have been banned. The current study investigated the efficacy of drinking water supplemented with essential oils and organic acids mixtures (EOA) on growth performance and intestinal health of broilers challenged with necrotic enteritis (NE). A total of 360 one-day-old Arbor Acres male broilers were randomly divided into 5 treatment groups, including non-challenged control group (T0), challenged NE group (T1), and challenged NE chickens treated with 0.

From Food Waste to Sustainable Agriculture: Nutritive Value of Potato By-Product in Total Mixed Ration for Angus Bulls.

Raw potato fries are a type of potato by-product (PBP), and they have great potential as a partial replacement of grain in animal feeds to improve the environmental sustainability of food production. This study aimed to investigate the effects of replacing corn with different levels of PBP (0%, 12.84%, 25.

The quantitative trait locus GWY10 controls rice grain width and yield.

A rice grain width and yield quantitative trait locus increases grain yield in near-isogenic lines and gene-edited lines and improves grain appearance and milling quality.

Improving Rice Grain Quality Through Ecotype Breeding for Enhancing Food and Nutritional Security in Asia-Pacific Region.

Rice grain is widely consumed as a staple food, providing essential nutrition for households, particularly marginalized families. It plays a crucial role in ensuring food security, promoting human nutrition, supporting good health, and contributing to global food and nutritional security. Addressing the diverse quality demands of emerging diverse and climate-risked population dietary needs requires the development of a single variety of rice grain that can meet the various dietary and nutritional requirements.

Machine learning trained poly (3,4-ethylenedioxythiophene) functionalized carbon matrix suspended Cu nanoparticles for precise monitoring of nitrite from pickled vegetables.

Precise monitoring of nitrite from real samples has gained significant attention due to its detrimental impact on human health. Herein, we have fabricated poly(3,4-ethylenedioxythiophene) functionalized carbon matrix suspended Cu nanoparticles (PEDOT-C@Cu-NPs) through a facile green synthesis approach. Additionally, we have used machine learning (ML) to optimize experimental parameters such as pH, drying time, and concentrations to predict current of the designed electrochemical sensor.

Effects of chlorogenic acid on productive and reproductive performances, egg quality, antioxidant functions, and intestinal microenvironment in aged breeder laying hens.

This study investigated the effects of dietary chlorogenic acid (CGA) on the productive and reproductive performance, egg quality, antioxidant function, and intestinal microenvironment of laying hens. Thus, 162 healthy Hy-Line Brown breeding hens (63 weeks old) were randomly allocated to 3 groups, each receiving a basal diet plus supplementation: 0, 250, and 500 mg/kg CGA, respectively. Per the in vitro test, CGA had obvious inhibitory effects on Salmonella enteritis and avian pathogenic Escherichia coli and strong free radical scavenging ability.

Antibiotic Cocktail Effects on Intestinal Microbial Community, Barrier Function, and Immune Function in Early Broiler Chickens.

This study investigated the effects of an antibiotic cocktail on intestinal microbial composition, mechanical barrier structure, and immune functions in early broilers. One-day-old healthy male broiler chicks were treated with a broad-spectrum antibiotic cocktail (ABX; neomycin, ampicillin, metronidazole, vancomycin, and kanamycin, 0.5 g/L each) or not in drinking water for 7 and 14 days, respectively.

Effects of microencapsulated essential oils and organic acids preparation on growth performance, slaughter characteristics, nutrient digestibility and intestinal microenvironment of broiler chickens.

To develop effective antibiotics alternatives is getting more and more important to poultry healthy production. The study investigated the effects of a microencapsulated essential oils and organic acids preparation (EOA) on growth performance, slaughter performance, nutrient digestibility and intestinal microenvironment of broilers. A total of 624 1-day-old male Arbor Acres broilers were randomly divided into 6 groups including the control group (T1) fed with basal diet, the antibiotic group (T2) supplemented with basal diet with 45 mg/kg bacitracin methylene disalicylate (BMD), and 4 inclusion levels of EOA-treated groups (T3, T4, T5, T6 groups) chickens given basal diet with 200, 400, 600, and 800 mg EOA/kg of diet, respectively.

The GW5-WRKY53-SGW5 module regulates grain size variation in rice.

Grain size is a crucial agronomic trait that affects stable yield, appearance, milling quality, and domestication in rice. However, the molecular and genetic relationships among QTL genes (QTGs) underlying natural variation for grain size remain elusive. Here, we identified a novel QTG SGW5 (suppressor of gw5) by map-based cloning using an F segregation population by fixing same genotype of the master QTG GW5.