Hepatitis A-Induced Fulminant Hepatic Failure Linked to Autoimmune Hepatitis in a Child Amidst Diagnostic Challenges of Dengue and Malaria.

Hepatitis A virus (HAV) typically causes a self-limiting illness in children. Rarely, it can progress to fulminant hepatic failure (FHF), and even less commonly, may be followed by features suggestive of autoimmune hepatitis (AIH). The diagnostic overlap can be particularly challenging in tropical regions, where endemic infections such as dengue and malaria may present with similar clinical features.

Yttrium-Doped Zinc Oxide (ZnYO) Electron Transport Layers: A Pathway to Enhanced Efficiency in PbS Colloidal Quantum Dot Solar Cells.

Significant progress has been achieved in PbS colloidal quantum dot solar cells (CQDSCs) by concentrating on structural engineering, band-alignment engineering, and enhancing the interfacial functionality of colloidal quantum dots (CQDs). Nonetheless, designing a durable and efficient photovoltaic device still represents a considerable obstacle for scientists in this domain. The present work demonstrates that the photovoltaic performance of PbS CQDSCs can be increased by adding 1-5 wt % yttrium into the zinc oxide (YZO) ETL.

Some novel optical pulses in hydrodynamical nonlinear complex equation using M-truncated fractional derivative.

This study investigates soliton solutions and dynamic wave structures in the complex Ginzburg-Landau (CGL) equation, which is crucial for understanding wave propagation in various physical systems. We employ three analytical methods: the Kumar-Malik method, the generalized Arnous method, and the energy balance method to derive novel closed-form solutions. These solutions exhibit diverse solitonic phenomena, including multi-wave solitons, complex solitons, singular solitons, periodic oscillating waves, dark-wave, and bright-wave profiles.

Development, physicochemical, and sensory analysis of moringa oleifera l. powder added buffalo milk yoghurt with pharmacological potential.

Yoghurt is a one of the commonly consumed nutritious dairy products, which lacks certain bioactive compounds that are present in abundance in many plants. While, a significant range of phytonutrients are present in the leaves of Moringa oleifera. Thus, the purpose of this work is to develop a functional yoghurt, which could promote the health of the consumers to its bioactive components.

Identification and green synthesis of potato dry rot Fusarium falciforme silver nanoparticles, characterization and antibacterial activity.

Potato tubers collected from different areas showed the prevalence of dry rot with characteristic white mycelia like symptoms of Fusarium pathogen. Fusarium species from diseased tubers were isolated based on morphological features. 18 S-Internal Transcribed Spacer (ITS) and Translation Elongation factor 1-α (TEF1-α) based analysis followed by phylogenetic tree constructed using ITS, TEF1-α and RNA polymerase II subunit B (RPB2) identified Fusarium isolates as Fusarium verticilloides, Fusarium soloni, Fusarium falciforme and Fusarium oxysporum.

A novel hesitant fuzzy tensor-based group decision-making approach with application to heterogeneous wireless network evaluation.

In decision environments characterized by vagueness and uncertainty, traditional models often struggle to accommodate the inherent hesitation in expert judgments. To address this challenge, this study introduces the novel concept of the Hesitant Fuzzy Tensor (HFT), a multidimensional extension of hesitant fuzzy sets, capable of representing multiple opinions across complex criteria spaces. The proposed HFT framework captures hesitation more effectively by organizing hesitant fuzzy data within tensorial structures, enabling more comprehensive analysis in group decision-making scenarios.

TEMSET-24K: Densely Annotated Dataset for Indexing Multipart Endoscopic Videos using Surgical Timeline Segmentation.

Indexing endoscopic surgical videos is vital in surgical data science, forming the basis for systematic retrospective analysis and clinical performance evaluation. Despite its significance, current video analytics rely on manual indexing, a time-consuming process. Advances in computer vision, particularly deep learning, offer automation potential, yet progress is limited by the lack of publicly available, densely annotated surgical datasets.

Fast Anomaly Detection for Vision-Based Industrial Inspection Using Cascades of Null Subspace PCA Detectors.

Anomaly detection in industrial imaging is critical for ensuring quality and reliability in automated manufacturing processes. While recently several methods have been reported in the literature that have demonstrated impressive detection performance on standard benchmarks, they necessarily rely on computationally intensive CNN architectures and post-processing techniques, necessitating access to high-end GPU hardware and limiting practical deployment in resource-constrained settings. In this study, we introduce a novel anomaly detection framework that leverages feature maps from a lightweight convolutional neural network (CNN) backbone, MobileNetV2, and cascaded detection to achieve notable accuracy as well as computational efficiency.

Understanding Photocatalytic Degradation of RB5 Dye under Salts Using Nickel Sulfide Nanoparticles: Insights from Dynamic Light Scattering and Theoretical Investigations.

This study reports the photocatalytic degradation of the RB5 dye by nickel sulfide nanoparticles (NiS NPs) in the presence of salts. Dynamic light scattering has rarely been used to study dye photocatalytic degradation. However, hydrodynamic size ( ) and zeta potential measurements offer insights into RB5 photocatalytic degradation.

Supersaturated Oxygen Delivery & Acute MI: Current Evidence, Practical Issues, and Future Research.

Introduction: Acute myocardial infarction is a significant global health issue, with a high mortality rate. Early intervention, specifically coronary angiography, has been shown to improve patient outcomes significantly. Recent technological advances have introduced novel therapeutic interventions like Supersaturated Oxygen (SSO2) Therapy, which promises enhanced recovery post-ischemia.

Novel closed-form travelling wave solutions for space-time fractional coupled Boussinesq-Burger model using extended direct algebraic method.

The nonlinear fractional partial differential equation known as the space-time fractional coupled Boussinesq-Burger equation (S TFcBBE) is examined in this work. Wave propagation in shallow water, fluid movement in dynamic systems, and wave propagation in nonlinear media are just a few of the physical processes it replicates. We derive new closed-form solutions for travelling waves, including a range of soliton waveforms, such as periodic, bell-type, kink-type, solitary kink, and multiple kink waves, by using the extended direct algebraic technique.

A programmed decline in ribosome levels governs human early neurodevelopment.

Many neurodevelopmental defects are linked to genes involved in housekeeping functions, such as those encoding ribosome biogenesis factors. How reductions in ribosome biogenesis can result in tissue- and developmental-specific defects remains unclear. Here we describe variants in the ribosome biogenesis factor AIRIM/C1orf109 that are primarily associated with neurodevelopmental disorders.

Rare case of refractory hypokalaemia in a patient with acute myelomonocytic leukaemia (AML M4): A case report.

A 39-year-old man, who was recently diagnosed with Acute Myelomonocytic Leukaemia (AML M4 subtype), presented at the Emergency Department of Ayub Teaching Hospital, Abbottabad, with all the common symptoms of AML, including anaemia, bleeding, and generalised weakness. What makes this case report interesting is the presence of severe refractory hypokalaemia. He was admitted to the Medical D unit of Ayub Teaching Hospital, Abbottabad, on January 14, 2024.

Biofumigation with carvacrol disrupts membrane integrity and metabolic homeostasis in yam leaf spot pathogen Alternaria alternata.

Alternaria alternata, a devastating fungal pathogen responsible for leaf spot diseases and postharvest rot across over 380 plant species, poses significant agricultural threats worldwide. Carvacrol, a plant-derived phenolic compound, exhibits robust antifungal properties, yet its biofumigation efficacy and molecular mode of action against A. alternata remain poorly characterized.

Cohousing-mediated microbiota transfer promotes bone health and modulates gut integrity, and immunity in young broiler chickens.

The intestine hosts a complex microbiota, which plays a crucial role in health and development. This study investigated the impact of cohousing day-old broilers with 14-day-old (CH14) or 42-day-old (CH42) broiler chickens and their fecal material for a week, compared to a non-cohoused control group. Birds were raised for 42 days, and bone traits, gut integrity and microbiota, cytokine and antimicrobial peptide profiles, and T cell immunity subsets were assessed at days 14 and 42.

Different types of anemia in patients with chronic kidney disease.

Objective: This study aimed to assess the prevalence of different anemia patterns in CKD patients.

Methods: This cross-sectional study was carried out at the Outpatient Department of General Medicine, Lady Reading Hospital, Peshawar from 1st July to 31 December, 2023. Non-probability consecutive sampling was employed.

NAV3 Missense Variant in a Homozygous State: Strengthening Links to Neurodevelopmental Disorder.

Introduction: Neurodevelopmental disorders (NDDs) represent a diverse and heterogeneous group of conditions, including neurodevelopmental delay (NDD), autism spectrum disorder (ASD), and neurodevelopmental encephalopathy with epilepsy (NDEE). While these disorders often share phenotypic similarities, their underlying genetic causes can vary widely, making clinical diagnosis challenging.

Methods: In this study, we performed whole-genome sequencing (WGS) on a family having an autosomal recessive neurodevelopmental disorder.

Development of an epitope-based vaccine from adhesion protein: addressing antibiotic resistance through immune-informatics.

is increasingly recognized for its role in severe health conditions, including sexually transmitted infections, ovarian and prostate cancer. The adhesion protein plays a crucial role in the pathogen's ability to attach to and invade host cells, making it a key target for vaccine development. The need to develop a vaccine against stems from its rising antibiotic resistance, limited treatments and effectiveness.

Optimization of short-circuit current density for tailored active region in BiFeO layer: a computational step into 3rd generation perovskite solar cells.

The global energy crisis has intensified the search for sustainable and clean energy alternatives, with solar energy emerging as a promising solution. The global energy crisis has intensified the search for sustainable and clean energy alternatives, with solar energy emerging as a promising solution. This study investigates the performance of BiFeO (BFO)-based perovskite solar cells using COMSOL Multiphysics simulations, focusing on the optimization of layer thicknesses and material properties.

A Novel Variant in the Cyto-Tail of Gene Underlying Isolated Postaxial Polydactyly.

Background: Polydactyly is one of the most common hereditary limb malformations, characterized by presence of additional digits in hands and/or feet. It is present either in isolated form or in combination with other features. Preaxial polydactyly with extra digit on the outside of the thumb or big toe, and postaxial polydactyly with extra digit on the outside of the little finger or little toe are the two main forms of polydactyly.

Gross-Pitaevskii systems of fractional order with respect to multicomponent solitary wave dynamics.

This study presents a comparative analysis of the fractional Gross-Pitaevskii equation (GPE), a fundamental nonlinear Schrödinger-type model, focusing on the derivation of exact soliton solutions critical for understanding nonlinear phenomena such as superfluidity and superconductivity. We compare the effectiveness of β-fractional and M-truncated fractional derivatives in solving the complex fractional GPE. This comparison reveals that while both fractional derivatives enable the construction of diverse optical soliton solutions-including hyperbolic, periodic, Jacobi elliptic, and exponential forms-the β-derivative provides smoother soliton profiles with computational simplicity, whereas the M-truncated derivative captures richer oscillatory dynamics due to its enhanced memory effects.

Genome-wide expression analysis of Festuca sinensis symbiotic with endophyte of reveals key candidate genes in response to nitrogen starvation.

Background: Nitrogen is one of the essential macronutrients bulk elements affecting plant growth and yield. However, the nitrogen content in most agricultural soils today is insufficient to meet the increasing demand for crop productivity. Festuca sinensis is an important cultivated forage grass found in high-altitude regions of China.

Synthesis, in vitro evaluation and computational modelling of benzene sulfonamide derivatives as Dickkopf 1 inhibitors for anticancer drug development.

In the modern age of drug discovery sulfanilamide derivatives are known to have great anti-cancerous potential, the current study aimed to synthesize these derivatives in order to evaluate their biological properties against carbonic anhydrase II (CA-II) and Dickkopf - 1(Dkk1) protein which are highly expressed in many cancers including lung cancer. A series of 10 sulfanilamide derivatives was synthesized under controlled conditions using reflux condensation method. Among all the synthesized derivatives (5a-5j), the compound 5d was found to possess highest antioxidant activity (90.