Associated transcription factors of allergic rhinitis: SP1 aggravates nasal epithelial barrier damage.

Allergic rhinitis (AR) is a respiratory airway disorder characterized by inflammation and barrier dysfunction. The transcription factor specificity protein 1 (SP1), a member of the Sp/Krüppel-like factor family, is known to be associated with inflammation. This study aimed to explore the impacts of SP1 on AR.

DeepRS: deep neural network-based in-service Rayleigh-scattering monitoring in bidirectional mode-division multiplexing systems.

In bidirectional mode-division multiplexing (Bi-MDM) systems, which have the potential for significantly higher transmission spectral efficiency, the complex interplay between mode-coupling and Rayleigh scattering (RS) exacerbates channel instability, posing significant challenges for dynamic network management. To address this, we propose DeepRS, an innovative deep-learning-based scheme for high-precision, in-service RS noise monitoring. By utilizing deep neural networks (DNNs) to extract features from the filtered frequency amplitude histogram (FFAH) of received signals, it enables the efficient signal-to-RS ratio (SRR) monitoring without disrupting signal traffic.

Endoscopic Endonasal Surgery of Skull Base Osteoradionecrosis with the Internal Carotid Artery Invaded: Clinical Characteristic and Surgical Strategy.

Objective: This study aims to summarize the clinical characteristics of skull base osteoradionecrosis (ORN) with the internal carotid artery (ICA) involvement and to distill the key surgical techniques that can enhance the protective measures for ICA.

Methods: We conducted a retrospective, observational study over a six-year period from February 2017 to May 2023. We included patients who were diagnosed with osteoradionecrosis with invasion of the internal carotid artery and collected their demographic information, pathology results, complication rates, ect.

Ant-colony optimization-based multi-input multi-output (ACO-MIMO) equalization for low-complexity mode-division multiplexing (MDM) processing.

In mode-division multiplexing (MDM) systems, the computational complexity of the multi-input multi-output (MIMO) equalization module is a critical obstacle to practical development. The step size μ and the number of taps K are key parameters in the equalization algorithm, influencing the performance of finite impulse response (FIR) equalizers, including convergence speed and output signal quality. To alleviate the computational burden of locating the optimal μ-K combination, we propose two ant colony optimization (ACO) -based MIMO equalization schemes: the fixed ACO-MIMO and the random ACO-MIMO, corresponding to two optimization strategies.

Multiplication-free and hardware-efficient baud-rate timing error detector for Nyquist and faster than Nyquist optical IM/DD systems.

Clock recovery (CR) algorithms that support higher baud rates and advanced modulation formats are crucial for short-distance optical interconnections, and it is desirable to push CR to operate at baud rate with minimal computing resources and power. In this Letter, we proposed a hardware-efficient and multiplication operation-free baud-rate timing error detector (TED) as a solution to meet these demands. Our approach involves employing both the absolute value of samples and the nonlinear sign operation to emphasize the clock tone, which is deteriorated by severe bandwidth limitation in Nyquist and faster than Nyquist (FTN) systems.

Silencing of forkhead box C1 reduces nasal epithelial barrier damage in mice with allergic rhinitis via epigenetically upregulating secreted frizzled-related protein 5.

Allergic rhinitis (AR) is caused by immunoglobulin E (IgE)-mediated reactions to inhaled allergens, which leads to mucosal inflammation and barrier dysfunction. The transcription factor forkhead box C1 (FOXC1) has been identified to be associated with allergic inflammation. This study sought to uncover the role of FOXC1 in AR.

Silica nanoparticles protect rice against biotic and abiotic stresses.

Background: By 2050, the world population will increase to 10 billion which urged global demand for food production to double. Plant disease and land drought will make the situation more dire, and safer and environment-friendly materials are thus considered as a new countermeasure. The rice blast fungus, Magnaporthe oryzae, causes one of the most destructive diseases of cultivated rice worldwide that seriously threatens rice production.

Electrostatic model of dielectric elastomer generator based on finite element.

When dielectric elastomer materials are used for power generation, bias voltage is applied at both ends of dielectric elastomer film, and there are equal amounts of heterogeneous charges on both sides of the film, so Maxwell electrostatic force is always coupled in the process of power generation. In order to investigate the distribution of Maxwell stress in dielectric elastomer material under electric field, the electrostatic model of dielectric elastomer generator is established in COMSOL finite element simulation software environment in this paper. The distribution of electrostatic force is studied from two aspects of theoretical derivation and simulation, and the magnitude and direction of electrostatic force are determined.

The regulatory role of SFRP5/WNT5A axis in allergic rhinitis through inhibiting JNK pathway activation and lowering mucin generation in human nasal epithelial cells.

Allergic rhinitis (AR) is tightly associated with type 2 inflammation. SFRP5 combined with WNT5A mainly inhibits chronic inflammatory response, atherosclerosis, and other metabolic disorders. However, the effect of SFRP5/WNT5A axis on recombinant human interleukin-13 (rhIL-13)-induced inflammation has not been studied.

[Osteoradionecrosis of skull base: clinical analysis and experience].

To discuss the diagnosis and treatment process of skull base osteoradionecrosis and improve the recognization of this disease. We reviewd skull base and nasopharyngeal osteoradionecrosis in 7 patients retrospectively, including 5 nasopharyngeal carcinoma, 1 squamous cell carcinoma of sphenoid sinus, 1 adenoid cystic carcinoma; 6 patientd received skull base debridement surgery and the other one attempted but failed because of her unstable condition. Follow-up period ranged from 3 to 31 months （mean 11.

Intriguing electronic and optical properties of two-dimensional Janus transition metal dichalcogenides.

Atomically thin Janus transition metal dichalcogenides (JTMDs) with an asymmetric structure have emerged as a new class of intriguing two-dimensional (2D) semiconductor materials. Using state-of-the-art density functional theory (DFT) calculations, we systematically investigate the structural, electronic, and optical properties of JTMD monolayers and heterostructures. Our calculated results indicate that the JTMD monolayers suffer from a bending strain but present high thermodynamic stability.

Hierarchical MoO/SnS core-shell nanowires with enhanced electrochemical performance for lithium-ion batteries.

Two-dimensional (2D) tin disulfide (SnS2) is a promising anode material for lithium-ion batteries (LIBs) because of its high theoretical capacity. The main challenges associated with the SnS2 electrodes are the poor cycling stability and low rate capability due to structural degradation in the discharge/charge process. Here, a facile two-step synthesis method is developed to fabricate hierarchical MoO3/SnS2 core-shell nanowires, where ultrathin SnS2 nanosheets are vertically anchored on MoO3 nanobelts to induce a heterointerface.

Effects of arthroscopic-assisted surgery on irreducible developmental dislocation of hip by mid-term follow-up: An observational study.

The purpose of this study was to investigate the indications, surgical technique, and the clinical effects of arthroscopic-assisted treatment of irreducible developmental dislocation of the hip by mid-term follow-up. Arthroscopic-assisted surgeries were performed on 40 children (52 hips) between January 2005 and December 2009. Anterior and antero-superior greater trochanter portals were used in these treatments.