Publications by authors named "Takuya Iimura"

Study Design: A multicenter prospective study.

Objective: To evaluate the effect of preoperative nutritional status, assessed using the Prognostic Nutritional Index (PNI), on clinical outcomes, including survival prognosis, postoperative complications, hospitalization duration, and functional prognosis, in patients with metastatic spinal tumors undergoing surgery.

Summary Of Background Data: Malnutrition is common in patients with cancer and is associated with poor clinical outcomes.

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The usefulness of spine stabilization for treating metastatic spinal tumors with tumor-induced instability has been reported. However, no reports have prospectively evaluated the effectiveness of adding posterior decompression to stabilization surgery for improving symptoms. This multicenter prospective study aimed to determine whether adding posterior decompression to spine stabilization surgery for metastatic spinal tumors affects postoperative outcomes and complications.

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Surgery for metastatic spinal tumors has improved postoperative activities of daily living. A few studies reported on prognostic factors assessed in large multicenter prospective studies for metastatic spinal tumors of lung cancer origin. This study aimed to determine preoperative prognostic factors in patients undergoing surgery for metastatic spinal tumors associated with lung cancer.

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Background: Posterior cervical foraminotomy for cervical spondylotic radiculopathy requires precise neural decompression while maintaining facet joint integrity. Ideally, the achievement of appropriate nerve root decompression should be confirmed using intraoperative computed tomography or other imaging modalities, although this is not generally done because of the need to avoid radiation exposure and/or because the procedure is very widely performed, even at facilities without expensive equipment. Magnetic resonance imaging (MRI)-ultrasound (US) fusion imaging has the potential to provide a simple radiation-free method of confirming successful neuroforaminal decompression.

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Background: Limited lumbar fusion surgery for adult spinal deformity (ASD) increases the risk of proximal junctional failure (PJF) at the thoracolumbar junction due to preserved mobility in this region. The majority of the extant research on PJF focuses on cases where the upper instrumented vertebra (UIV) is in the thoracic spine, whereas the aim of this study was to evaluate the correlation between Hounsfield Unit (HU) values around the thoracolumbar junction and the incidence of PJF following limited lumbar fusion.

Methods: A retrospective review identified patients aged ≥ 40 years who underwent fusion surgery spanning ≥ 3 levels with a UIV in the upper lumbar spine (L1-L3) and had a follow-up of at least two years.

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Study Design: Prospective multicenter study.

Objective: To investigate risk factors for 3-month postoperative mortality in metastatic spinal tumor surgery, focusing on nutritional biomarkers and prognostic scores alongside clinical indicators.

Summary Of Background Data: Metastatic spinal tumors affect patient morbidity and mortality.

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Background: Advancements in understanding spinal disorders and diagnostic techniques have increased the range and complexity of spinal surgeries. However, constraints have arisen in gaining experience techniques through actual surgical cases due to considerations of medical safety, efficiency in working hours, and cost-effectiveness. As such, off-the-job training is expected to play an increasingly significant role.

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Study Design: Retrospective analysis of data collected across multiple centers.

Objective: To develop machine learning models for predicting neurological outcomes one month postoperatively in patients with metastatic spinal tumors undergoing surgery, and to identify key factors influencing neurological recovery.

Summary Of Background Data: The increasing prevalence of spinal metastases has led to a growing need for surgical intervention to address mechanical instability and neurological deficits.

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Introduction: Patients with adult spinal deformity (ASD) lean forward with their trunks when walking, even if they can remain upright during static standing. However, it remains unclear which part of the spinal column is involved in forward trunk tilt and the details of the relationships between sagittal alignment during static standing and changes in dynamic parameters during walking. Therefore, this study aimed to clarify the above by analyzing the walking motion of ASD patients using inertial measurement units (IMUs).

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Article Synopsis
  • The study examines how the preoperative Spine Instability Neoplastic Score (SINS) relates to surgical decisions and patient outcomes in spinal metastases patients.
  • The research involved 317 patients and assessed various factors like surgery type, existing conditions, and postoperative health indicators over 6 months.
  • Findings revealed that SINS did not correlate with life expectancy, all patient-reported outcomes improved post-surgery, and surgical approach (especially fusion vs. non-fusion) didn't significantly impact these outcomes.
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Study DesignProspective multicenter study.ObjectivesPalliative surgery is crucial for maintaining the quality of life (QOL) in patients with spinal metastases. This study aimed to compare the short-term outcomes of QOL after palliative surgery between patients with metastatic spinal tumors at different segments.

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Article Synopsis
  • The study investigated the postoperative outcomes for patients with spinal metastases from prostate cancer, focusing on improvements in their quality of life and other patient-oriented assessments.
  • Conducted across 35 centers, the research assessed 413 patients, with 41 specifically having prostate cancer, and followed them for at least a year following surgery using various evaluation methods.
  • Results showed significant improvements in neurological function, quality of life, and patient motivation post-surgery, indicating that surgical intervention is beneficial for these patients.
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Article Synopsis
  • The study aimed to determine minimal clinically important differences (MCIDs) for patients undergoing surgery for spinal metastases to improve patient care by linking quality of life assessments with clinical outcomes.
  • A total of 171 patients were evaluated pre- and post-surgery using various scales, leading to the identification of specific MCID values for different quality of life aspects based on their treatment outcomes.
  • The study successfully established both anchor-based and distribution-based MCIDs for surgical interventions, which can help in assessing patient progress and overall treatment effectiveness.
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Background: The natural history of the congenital spinal deformity and its clinical magnitude vary widely in human species. However, we previously reported that the spinal deformities of congenital scoliosis mice did not progress throughout our observational period according to soft X-ray and MRI data. In this study, congenital vertebral and intervertebral malformations in mice were assessed via magnetic resonance (MR) and histological images.

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Background: The uniqueness of spinal sagittal alignment in thoracic adolescent idiopathic scoliosis (AIS), for example, the drastically smaller thoracic kyphosis seen in some patients, has been recognized but not yet fully understood. The purpose of this study was to clarify the characteristics of sagittal alignment of thoracic AIS and to determine the contributing factors.

Methods: Whole spine radiographs of 83 thoracic AIS patients (73 females) were analyzed.

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Objective: Previous studies have demonstrated that Lenke lumbar modifier A contains 2 distinct types (AR and AL), and the AR curve pattern is likely to develop adding-on (i.e., a progressive increase in the number of vertebrae included within the primary curve distally after posterior surgery).

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Objective: The aim of this study was to show the surgical results of growing rod (GR) surgery with prior foundation surgery (PFS) and sublaminar taping at an apex vertebra.

Methods: Twenty-two early-onset scoliosis (EOS) patients underwent dual GR surgery with PFS and sublaminar taping. PFS was performed prior to rod placement, including exposure of distal and proximal anchor areas and anchor instrumentation filled with a local bone graft.

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Objectives: It is controversial whether to stop the fusion at L5 or S1 in adult spinal deformity (ASD) surgery. Our hypothesis is that we can stop long fusion at L5 for selected patients with less severe disability and less complex deformity. Aim was to compare minimum 5-year outcomes between ASD patients with fusion to L5 versus S1.

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