A mini-review on heavy metals accumulation in seaweed of India: prospects for phyco-remediation.

Heavy metals are major contaminants introduced through various anthropogenic and geogenic activities, affecting and altering the quality of coastal water bodies where seaweed inhabits. Metal contamination poses a significant threat to aquatic and human health. Among different remediation methods for these pollutants, phyco-remediation is emerging as an effective strategy due to the metal's accumulation potential in the seaweed and its feasibility.

Hydrogen Oxidation by Bioinspired Models of [FeFe]-Hydrogenase.

Synthetic azadithiolate-bridged diiron clusters serve as structural analogues of the active site of [FeFe]-hydrogenases. Recently, an alkyl substitution of aniline-based azadithiolate bridge allowed these synthetic models to both oxidize H and reduce H, i.e.

Functional Nonheme Diiron(II) Complexes Catalyze the Direct Reduction of Nitrite to Nitric Oxide in Relevance to the Diiron Protein YtfE.

The present work reports the functional modeling chemistry of YtfE, which features a nonheme diiron active site and mediates the direct reduction of NO to NO. The model complex, [Fe(HPTP)Cl] (), reduces NO to NO in a 100% yield within 12 h and generates [Fe(HPTP)(μ-O)(μ-OH)] (). Similar to YtfE, the reaction involves stepwise oxidation of two Fe(II) centers and product (NO) inhibition, of which the latter produces [Fe(HPTP)(NO)Cl] ().

Rare Masqueraders of Pure Neuritic Leprosy: A Report of Four Cases.

Introduction: Hansen's disease is a chronic, infective granulomatous skin disease with a wide array of manifestations that resemble many dermatological and neurological conditions. Pure neuritic Hansen's disease is a familiar form among leprosy physicians, and it poses significant diagnostic difficulty. Various disorders can mimic leprosy neuropathy clinically and these patients may receive multidrug therapy in endemic areas due to the commonality of leprosy.

Trypsinized suction blister.

Suction blister epidermal grafting (SBEG) is a standard technique for treating vitiligo on challenging areas like fingertips and lips but often results in pigment halos and difficulties with small, curved surfaces. We propose a modified SBEG technique, utilizing trypsinization of one blister graft to improve melanocyte spread and reduce peri-graft halo. Trypsin ethylenediaminetetraacetic acid (EDTA) solution is introduced into a selected blister, creating a cell suspension applied to dermabraded gaps and peripheries, including eyelid margins.

Clinical and dermoscopic profile of non-venereal genital dermatoses and its impact on the quality of life: A cross-sectional study of 550 cases.

Background Non-venereal genital dermatoses cover a broad spectrum of conditions with varying aetiologies and can be confused with venereal disorders. This may cause significant anxiety to the patient as well as diagnostic difficulties for the clinician. Objective The purpose was to study the clinico-epidemiological pattern of non-venereal genital dermatoses along with their dermoscopic features and to assess their impact on the quality of life.

Comparing the Efficacy of Combined Intralesional Triamcinolone Acetonide With Topical Calcipotriol Versus Intralesional Triamcinolone Acetonide Monotherapy in Scalp and Beard Alopecia Areata: Results From a Randomized Single-Blinded Clinical Trial.

Background: Intralesional (IL) steroids are the first-line treatment option for localized alopecia areata (AA). The present study aimed to compare the efficacy of topical calcipotriol with IL triamcinolone acetonide versus IL triamcinolone acetonide alone in AA.

Methods: This randomized single-blinded clinical trial was conducted in a dermatology outpatient department.

Synthesis of ethane from CO by a methyl transferase-inspired molecular catalyst.

Molecular catalysts with a single metal center are reported to reduce CO to a wide range of valuable single-carbon products like CO, HCOOH, CHOH, etc. However, these catalysts cannot reduce CO to two carbon products like ethane or ethylene and the ability to form C-C from CO remains mostly limited to heterogeneous material-based catalysts. We report a set of simple iron porphyrins with pendant thiol group can catalyze the reduction of CO to ethane (CH) with HO as the proton source with a Faradaic yield >40% the rest being CO.

Reduction of Nitrite in an Iron(II)-Nitrito Compound by Thiols and Selenol Produces Dinitrosyl Iron Complexes via an {FeNO} Intermediate.

Reaction of an Fe(II) complex, [Fe(6-COO-tpa)] (), with PhE and NO produced [Fe(6-COO-tpa)(EPh)] (E = S, ; Se, ) and [Fe(6-COO-tpa)κO,O'-NO)] (), respectively (6-COOH-tpa is bis(2-pyridylmethyl)(6-carboxyl-2-pyridylmethyl)amine). Treatment of with 2 equiv of PhEH (E = S, Se) produced NO in ∼40% yields, respectively, along with and the DNICs, [Fe(EPh)(NO)] (E = S, Se). Treatment of with excess PhEH produced NO in similar yields, while was converted to the same DNICs and / (instead of ).

Noncultured epidermal suspension procedure of vitiligo surgery using freeze-dried trypsin coated on silicon pellets.

Non-cultured epidermal suspension technique is currently the surgical treatment of choice for vitiligo. Storage of trypsin ethylenediaminetetraacetic acid solution has a stringent requirement. We propose usage of freeze-dried trypsin for the procedure which can be kept in usual refrigerator at 2-8°C.

Efficacy of apremilast in hyperkeratotic hand and foot dermatitis: results from a randomized observer-blinded comparative study.

Background: Hyperkeratotic hand and foot dermatitis significantly affects quality of life. Some patients respond suboptimally to topical corticosteroids and have multiple recurrences.

Objective: Our aim was to compare the efficacy and safety profile of apremilast and topical corticosteroid versus corticosteroid alone in hyperkeratotic hand and foot dermatitis.

Reactivity of Thiolate and Hydrosulfide with a Mononuclear {FeNO} Complex Featuring a Very High N-O Stretching Frequency.

Synthesis, characterization, electronic structure, and redox reactions of a mononuclear {FeNO} complex with a very high N-O stretching frequency in solution are presented. Nitrosylation of [(L)Fe(DMF)] () (L = tris((1-methyl-4,5-diphenyl-1H-imidazol-2-yl)methyl)amine) produced a five-coordinate {FeNO} complex, [(L)Fe(NO)] (). While complex could accommodate an additional water molecule to generate a six-coordinate {FeNO} complex, [(L)Fe(NO)(HO)] (), the coordinated HO in dissociates to generate in solution.

Kinetic isotope effect offers selectivity in CO reduction.

A binuclear Ni complex with N,O donors catalyzes CO reduction its Ni(I) state. The product distribution when HO is used as a proton source shows similar yields for CO, HCOOH and H. However, when DO is used, the product distribution shows a ∼65% selectivity for HCOOH.

Facile electrocatalytic proton reduction by a [Fe-Fe]-hydrogenase bio-inspired synthetic model bearing a terminal CN ligand.

An azadithiolate bridged CN bound pentacarbonyl bis-iron complex, mimicking the active site of [Fe-Fe] Hase is synthesized. The geometric and electronic structure of this complex is elucidated using a combination of EXAFS analysis, infrared and Mössbauer spectroscopy and DFT calculations. The electrochemical investigations show that complex 1 effectively reduces H to H between pH 0-3 at diffusion-controlled rates (10 M s) 10 s at pH 3 with an overpotential of 140 mV.

An unusual co-reactivation of herpes genitalis and shingles in a young male with primary genital herpes in partner.

Background: Herpes simplex virus type 2 (HSV-2) is the most common cause of genital ulcers in industrialized countries. Herpes zoster (HZ) is an acute, cutaneous viral infection caused by the reactivation of the varicella-zoster virus (VZV).

Case Summary: A 27-year-old male presented with painful vesicles over the trunk for the last 5 days with painful genital erosions for the last 2 days.