Athletic Identity and Performance Anxiety among University Athletes: Moderating Role of Perceived Coaching Styles.

Background: In the competitive world of emerging athletes, performance is crucial; in sports, it is essential. However, under the spotlight of competition, performance anxiety lurks as the unseen rival every athlete must conquer. Two important factors are fundamental to this dynamic-athletic identity and perceived coaching styles.

Astringent Effects of Red Wine Associated with Responses of Aquaporins Found in Human Tongue and Salivary Tissues.

Aquaporin (AQP) water channels facilitate fluid transport across cell membranes, are implicated in rodent oral water sensing, and were examined in the human tongue for their modulation by mouthfeel compounds and ensuing effects on perception and saliva tribology. Immunohistochemistry demonstrated abundant AQP1 and AQP2 and moderate AQP5 in human tongue and high AQP5 in salivary gland. Trained human tasting panels evaluated astringency intensities; results correlated with wine tannin measures and inhibition of AQP1 water flux ( ≥ 0.

Feasibility and Clinical Utility of Low-Field Magnetic Resonance Imaging in Critically Ill Children: An Experience from Pakistan.

Background: Low-field portable magnetic resonance imaging (pMRI) systems have been approved for clinical use, but their feasibility, efficacy, and most appropriate clinical application in children are unknown. The objective of this study was to evaluate the diagnostic accuracy of pMRI in detecting acute brain injury (ABI) in critically ill children compared to conventional MRI (cMRI) and or computed tomography (CT).

Methods: This prospective diagnostic accuracy study included children (1 month to < 18 years) admitted between May 2021 and June 2022 who underwent pMRI scans within a 24-h window of standard neuroimaging (CT or cMRI).

LocustLens: leveraging environmental data fusion and machine learning for desert locust swarm prediction.

The desert locust is one of the most destructive locusts recorded in human history, and it has caused significant food shortages, monetary losses, and environmental calamities. Prediction of locust attacks is complicated as it depends on various environmental and geographical factors. This research aims to develop a machine-learning model for predicting desert locust attacks in 42 countries that considers three predictors: soil moisture, maximum temperature, and precipitation.

Impact of GLP-1 Receptor Agonist Use in Patients With Steatotic Liver Disease and Type 2 Diabetes: A Retrospective Cohort Study.

Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) help manage type 2 diabetes (T2DM) and may have efficacy in steatotic liver disease. To determine the prevalence and clinical impact of GLP-1 RA use in patients with T2DM and liver disease. This was a retrospective study of adult patients with T2DM and nonalcoholic fatty liver disease (NAFLD), nonalcoholic fatty liver (NAFL), or nonalcoholic steatohepatitis (NASH) between 1/1/21-12/31/21.

Antimicrobial consumption in an acute NHS Trust during the COVID-19 pandemic: intervention time series analysis.

Objective: To determine the impact of the COVID-19 pandemic on antimicrobial consumption and trends of therapeutic drugs for COVID-19 treatments, including corticosteroids, remdesivir and monoclonal antibodies (tocilizumab) from April 2017 to September 2022 in a secondary care NHS Trust in England.

Methods: A retrospective intervention time series analysis was conducted for April 2017 to September 2022 at the Mid Yorkshire Teaching NHS Trust. Data were retrieved from the pharmacy dispensing system as defined daily doses (DDDs) monthly and reported per 1000 occupied bed days (OBDs).

Consanguinity in northwest Pakistan: evidence of temporal decline.

Pakistan has a high burden of hereditary and congenital anomalies and their incidence rate almost doubles against the background of parental consanguinity. Consanguineous unions (CU) are customary in Pakistan and deeply rooted socio-cultural norms favour CU. This study aimed to elucidate the determinants and temporal change in CU in four northwestern populations of Pakistan.

Investigation and optimization of In-Vitro behaviour of Perovskite barium titanate as a scaffold and protective coatings.

The piezoelectric effect is widely known to have a significant physiological function in bone development, remodeling, and fracture repair. As a well-known piezoelectric material, barium titanate is particularly appealing as a scaffold layer to improve bone tissue engineering applications. Currently, the chemical bath deposition method is used to prepare green synthesized barium titanate coatings to improve mechanical and biological characteristics.

Reducing the Invasiveness of Low- and High-Grade Endometrial Cancers in Both Primary Human Cancer Biopsies and Cell Lines by the Inhibition of Aquaporin-1 Channels.

Aquaporin (AQP) channels in endometrial cancer (EC) cells are of interest as pharmacological targets to reduce tumor progression. A panel of compounds, including AQP1 ion channel inhibitors (AqB011 and 5-(phenoxymethyl) furan-2-carbaldehyde, PMFC), were used to test the hypothesis that inhibition of key AQPs can limit the invasiveness of low- and high-grade EC cells. We evaluated the effects on transwell migration in EC cell lines (Ishikawa, MFE-280) and primary EC cells established from surgical tissues ( = 8).

Metastatic Renal Cell Carcinoma: An Enigmatic Nasal Mass.

Metastatic Renal Cell Carcinoma rarely presents in head and neck and is even rarer in the sinonasal region. However, a sinonasal metastatic mass is usually of RCC origin. These metastases may present prior to the renal symptoms or may appear after primary treatment.

Clinical outcomes associated with blood-culture contamination are not affected by utilization of a rapid blood-culture identification system.

Objective: Contaminated blood cultures result in extended hospital stays and extended durations of antibiotic therapy. Rapid molecular-based blood culture testing can speed positive culture detection and improve clinical outcomes, particularly when combined with an antimicrobial stewardship program. We investigated the impact of a multiplex polymerase chain reaction (PCR) FilmArray Blood Culture Identification (BCID) system on clinical outcomes associated with contaminated blood cultures.