98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11833326 | PMC |
http://dx.doi.org/10.2340/actadv.v105.42948 | DOI Listing |
Biology (Basel)
August 2025
Department of Dermatology, Zealand University Hospital, 4000 Roskilde, Denmark.
Superficial fungal infections of the feet, such as tinea pedis and onychomycosis, are highly prevalent and frequently recurrent, often due to persistent contamination of footwear, textiles, and foot care instruments. Despite growing concern over antifungal resistance, environmental sources of reinfection remain under-recognized in clinical practice. This review critically examines historical and contemporary methods used to sanitize shoes, socks, podiatric tools, and related materials.
View Article and Find Full Text PDFBMC Complement Med Ther
September 2025
Department of Dermatology and Venereology, Noakhali Medical College, Noakhali, 3821, Bangladesh.
The increasing incidence of dermatophytic infections and rising resistance to conventional antifungal agents necessitates the exploration of alternative therapies. This study investigates the antifungal potential of Curcuma longa rhizome extract against dermatophytes, particularly Trichophyton species, through a combination of in vitro and in silico techniques. The methanolic extract of Curcuma longa was evaluated for its antifungal efficacy using the disc diffusion method against Trichophyton mentagrophytes, Trichophyton indotineae, and Trichophyton interdigitale.
View Article and Find Full Text PDFMed Mycol J
August 2025
Division of Clinical Laboratory, Teikyo University Chiba Medical Center.
In Japan, two topical drugs and three oral antifungal drugs are prescribed for onychomycosis. Fosravuconazole L-lysine ethanolate (F-RVCZ) is an azole antifungal drug that has been prescribed in Japan since 2018 for the oral treatment of onychomycosis. Herein, we review the real-world evidence of F-RVCZ treatment for cutaneous fungal infection in Japan.
View Article and Find Full Text PDFLife (Basel)
August 2025
Mediprobe Research Inc., London, ON N5X 2P1, Canada.
Onychomycosis is a prevalent and clinically relevant complication among individuals with diabetes. It is associated with an elevated risk of secondary fungal and bacterial infections, foot ulceration, and, in advanced cases, amputation. Factors contributing to the increased prevalence of onychomycosis in this population include age, peripheral vascular disease, poor glycemic control, neuropathy, suboptimal foot hygiene, and nail trauma.
View Article and Find Full Text PDFGels
July 2025
Bioscience Research Institute, Technological University of the Shannon, N37 HD68 Athlone, Westmeath, Ireland.
Fungal infections pose a significant yet under-recognised global health burden, affecting over one billion individuals annually and contributing to approximately 2.5 million direct deaths. The World Health Organisation (WHO) has recently reemphasised this issue through the publication of its Fungal Priority Pathogens List (FPPL) and its 2025 report evaluating current antifungal diagnostics and therapeutics.
View Article and Find Full Text PDF