Astringent Effects of Red Wine Associated with Responses of Aquaporins Found in Human Tongue and Salivary Tissues.

Aquaporin (AQP) water channels facilitate fluid transport across cell membranes, are implicated in rodent oral water sensing, and were examined in the human tongue for their modulation by mouthfeel compounds and ensuing effects on perception and saliva tribology. Immunohistochemistry demonstrated abundant AQP1 and AQP2 and moderate AQP5 in human tongue and high AQP5 in salivary gland. Trained human tasting panels evaluated astringency intensities; results correlated with wine tannin measures and inhibition of AQP1 water flux ( ≥ 0.

Ovary of the southern hairy-nosed wombat (Lasiorhinus latifrons): its divergent structural organisation.

The organisation of the ovarian interstitial tissue in the southern hairy-nosed wombat Lasiorhinus latifrons was investigated. Unlike in most other marsupials, the outer cortical region of the ovary contains abundant luteinised interstitial tissue that largely occurs in discrete lobules, many of which contain a localised area of non-cellular, highly eosinophilic and periodic acid-Schiff-positive material. The findings suggest that the latter arises from the zona pellucida that surrounded the oocyte in growing follicles and that the luteinised interstitial tissue thus developed from transformed theca interna of degenerated atretic follicles.

Systematic review and meta-analysis of outcomes after cardiopulmonary arrest in childhood.

Background: Cardiopulmonary arrest in children is an uncommon event, and often fatal. Resuscitation is often attempted, but at what point, and under what circumstances do continued attempts to re-establish circulation become futile? The uncertainty around these questions can lead to unintended distress to the family and to the resuscitation team.

Objectives: To define the likely outcomes of cardiopulmonary resuscitation in children, within different patient groups, related to clinical features.

Whole-body heat exposure induces membrane changes in spermatozoa from the cauda epididymidis of laboratory mice.

This study was carried out to determine if exposure to hot environmental temperatures had a direct, detrimental effect on sperm quality. For this the effect of whole-body heat exposure on epididymal spermatozoa of laboratory mice was investigated. C57BL/6 mice (n = 7) were housed in a microclimate chamber at 37 degrees C-38 degrees C for 8 h per day for three consecutive days, while control mice (n = 7) were kept at 23 degrees C-24 degrees C.