State Anxiety Modulates Conflict Control Depending on Cognitive Control Context: Evidence From Behavioral and ERP Data.

The impact of state anxiety on conflict control and its neural mechanisms, particularly in relation to proactive versus reactive control, remains incompletely understood. Therefore, we conducted two experiments to investigate how state anxiety affects conflict control across different control contexts and to explore the associated temporal dynamics. The threat of shock paradigm was employed to induce state anxiety.

Untargeted metabolomics analysis reveals comparative meat quality of different muscles and the impact of Saline-alkali land feeding on Dolang sheep (Ovis aries).

As an important meat resource, lamb has a wide consumer market worldwide. Dolang sheep of Xinjiang are renowned for their tender meat and unique flavor, and the quality of mutton is remarkably influenced by the saline-alkali environment. Therefore, this study aimed to explore the differences in meat quality between different parts of Dolang sheep and the meat quality under different rearing conditions in Shache and Bachu, Kashgar.

Bioadhesive chitosan hydrogel with dynamic covalent bonds and sustained kartogenin release for endogenous cartilage regeneration.

Articular cartilage defects are clinically prevalent yet lack effective therapeutic solutions. Recent advancements in acellular cartilage tissue engineering combined with microfracture techniques have shown promising outcomes. Injectable hydrogels have emerged as particularly attractive scaffolds due to their minimally invasive implantation and capacity to conform to irregular cartilage defects.

Genetic Evaluation of Early Growth Traits in Yunnan Semi-Fine Wool Sheep.

With economic development and improved living standards, the demand for mutton and wool continues to grow, and improving the production performance and genetic potential of sheep breeds has become the key to promoting the high-quality development of the sheep industry. Thus, this study analyzes the influencing factors of the early production traits of Yunnan semi-fine wool sheep, optimizes the genetic evaluation model, and relies on accurate genetic parameter estimation to provide a theoretical basis for formulating a scientific and efficient breeding strategy for this breed. Data were collected from the Laishishan and Xiaohai breeding farms in Qiaojia, Yunnan, covering production records of the core flock from 2018 to 2022.

The effect of Kellgren-Lawrence grade on functional outcome following medial unicompartmental knee arthroplasty in patients with partial thickness cartilage loss.

Introduction: Medial unicompartmental knee arthroplasty (mUKA) is indicated for anteromedial osteoarthritis (AMOA) with medial full thickness cartilage loss (FTCL). Previous studies have reported controversial outcomes in patients with partial thickness cartilage loss (PTCL) who undergo mUKA. However, there is no reliable way to predict which PTCL patients do well.

Proteomics Reveals the Role of PLIN2 in Regulating the Secondary Hair Follicle Cycle in Cashmere Goats.

Based on comprehensive proteomic analysis conducted across various stages of secondary hair follicles (SHFs), the growth and development regulatory mechanisms of SHFs in Jiangnan cashmere goats were studied. Proteomic analysis of skin tissue from the SHF anagen (An), catagen (Cn), and telogen (Tn) revealed 145 differentially expressed proteins (DEPs) between the An and Tn, 53 DEPs between the Cn and An, and 168 DEPs between the Cn and Tn. Gene Ontology (GO) annotations indicated that the DEPs were predominantly involved in keratin filament formation (KRTAP3-1, KRT1, KRT8), intermediate filament formation (KRT26, KRT35, KRT19, etc.

Silencing Livin gene expression by RNA interference enhanced the chemotherapeutic sensitivity of drug-resistant osteosarcoma cells to doxorubicin.

Background: Osteosarcoma is one of the most common malignant tumors in children and adolescents. It occurs in the metaphysis of long bones and is a type of aggressive malignant tumor. Although there are treatment methods such as surgery and chemotherapy, the mortality and disability of osteosarcoma patients are still high.

Ribosomal translation of fluorinated non-canonical amino acids for biologically active fluorinated macrocyclic peptides.

Fluorination has emerged as a promising strategy in medicinal chemistry to improve the pharmacological profiles of drug candidates. Similarly, incorporating fluorinated non-canonical amino acids into macrocyclic peptides expands chemical diversity and enhances their pharmacological properties, from improved metabolic stability to enhanced cell permeability and target interactions. However, only a limited number of fluorinated non-canonical amino acids, which are canonical amino acid analogs, have been incorporated into macrocyclic peptides by ribosomes for construction and target-based screening of fluorinated macrocyclic peptides.

Transcriptome meta-analysis reveals the hair genetic rules in six animal breeds and genes associated with wool fineness.

Wool plays an irreplaceable role in the lives of livestock and the textile industry. The variety of hair quality and shape leads to the diversity of its functions and applications, and the finer wool has a higher economic value. In this study, 10 coarse and 10 fine ordos fine wool sheep skin samples were collected for RNA-seq, and coarse and fine skin/hair follicle RNA-seq datasets of other five animal breeds were obtained from NCBI.

Comparison of different animal models for estimating genetic parameters for early growth traits and reproductive traits in Tianmu Sainuo sheep.

As the economic level of individuals rises, so too does the demand for mutton. Enhancing the breeds of mutton sheep not only boosts production efficiency and economic benefits but also fosters the sustainable growth of the mutton sheep breeding industry. Thus, this study examines the early growth and reproductive traits of Tianmu Sainuo sheep, analyzing the genetic interactions among these traits to furnish a theoretical foundation for refining breeding strategies and expediting the genetic advancement of this breed.

A study on the influence of perceived distance on China's inbound Tourism and the interaction of non-economic distance: An analysis of dynamic extended gravity model based on 61 countries' entry data (2004-2018).

In the post-epidemic era, the restart of China's inbound tourism is imminent. However, there are gaps in our current understanding of how distance perception dynamically affects inbound tourism in China. In order to understand the past patterns of inbound tourism in China, we mapped the data of 61 countries of origin from 2004 to 2018 into a dynamic expanding gravity model to understand the effects of cultural distance, institutional distance, geographical distance, and economic distance on inbound tourism in China and revealed the dynamic interaction mechanism of non-economic distance perception on inbound tourism in China.

The Gradient Effect on Cyclic Behavior of 316L Stainless Steel in the Ultrasonic Bending Test.

Nanoindentation measurements were conducted to investigate the high-cycle response of 316L stainless steel in bending fatigue. Hardness variation owing to the gradient flexure stress amplitude for different curvatures was plotted along with the thickness and length, respectively. Scanning electron microscopy (SEM) was subsequently conducted to explore the deformation characteristics in multiple layers, which had cyclic gradient stress, on the cross-section of specimens.

Extraction and Surface Functionalization of Cellulose Nanocrystals from Sugarcane Bagasse.

The present study aimed to optimize the process for extracting cellulose nanocrystals (CNCs) from sugarcane bagasse through ultrasonic-assisted sulfuric acid hydrolysis and its subsequent modification with L-malic acid and silane coupling agent KH-550. The effects of the different modification methods and the order of modification on the structures and properties of bagasse CNCs were explored. The results indicated that the optimal process conditions were achieved at an acid-digestion temperature of 50 °C, a reaction time of 70 min, an ultrasonic power of 250 W, and a volume fraction of 55%.

Cyclic Deformation and Fatigue Failure Mechanisms of Thermoplastic Polyurethane in High Cycle Fatigue.

In this study, the main purpose is to analyze the fatigue failure of thermoplastic polyurethane (TPU) plate under tension-tension load control tests (frequency = 5 Hz, stress ratio = 0.1) and consider the change in hydrogen bond content. The results show that the S-N curve of TPU material shows a downward trend before reaching the fatigue limit (10.

A Novel Ultrasonic Fatigue Test and Application in Bending Fatigue of TC4 Titanium Alloy.

The very high cycle fatigue (VHCF) problems of thin-plate structures are usually caused by high-frequency vibrations. This paper proposes an accelerated fatigue test method based on ultrasonic loading technology in order to develop a feasible bending testing method and explore the bending fatigue characteristics of thin-plate structures in the VHCF regime. A new bending fatigue specimen with an intrinsic frequency of 20 kHz was designed based on cantilever bending through finite element simulation.

A Novel Model of Ultrasonic Fatigue Test in Pure Bending.

The very high cycle fatigue (VHCF) failure of in-service components is mainly caused by the vibration of thin-wall elements at a high frequency. In this work, a novel model of ultrasonic fatigue test was developed to test thin-wall material in bending up to VHCF with an accelerated frequency. The theoretical principle and finite element analysis were introduced for designing a sample that resonated at the frequency of 20 kHz in flexural vibration.

Bone marrow mesenchymal stem cell-derived exosomes inhibit chondrocyte apoptosis and the expression of MMPs by regulating Drp1-mediated mitophagy.

Osteoarthritis (OA) is a joint degenerative disease commonly seen in the elderly. Bone marrow mesenchymal stem cell-exosomes (BMSC-exosomes) are closely associated with the progression of OA. Here, we investigated whether BMSC-exosomes can affect OA development by regulating mitophagy.

The Identification of Mutation in Gene Associated with Litter Size in Xinjiang Cele Black Sheep.

The Bone Morphogenetic Protein 15 () gene is known to have multiple single-nucleotide polymorphism sites associated with sheep fecundity. This study used gene sequence analysis and mutation detection assays for by using 205 blood samples of ewes with known lambing records. Sequence analysis showed that mutation B1 missed the CTT base in exon 1 at positions 28-30, leading to a leucine deletion in the BMP15 protein.

Predicting Protein Surface Property with its Surface Hydrophobicity.

This article reviews and discusses the relationship between surface hydrophobicity and other surface properties of proteins and the possibility of using surface hydrophobicity as a key indicator to predict and evaluate the changes in the surface properties of a protein. Hydrophobicity is the main driving force of protein folding; it affects the structure and functions. Surface hydrophobicity and other surface properties of proteins are controlled by their spatial structures.

Using High-Density SNP Array to Reveal Selection Signatures Related to Prolificacy in Chinese and Kazakhstan Sheep Breeds.

Selection signature provides an efficient tool to explore genes related to traits of interest. In this study, 176 ewes from one Chinese uniparous breed and three Kazakhstan multiparous breeds are genotyped using Affymetrix 600K HD single nucleotide polymorphism (SNP) arrays, F-statistics (Fst), and a Cross Population Extend Haplotype Homozygosity Test (XPEHH). These are conducted to identify genomic regions that might be under selection in three population pairs comprised the one multiparous breed and the uniparous breed.

Selective recovery of vanadium and scandium by ion exchange with D201 and solvent extraction using P507 from hydrochloric acid leaching solution of red mud.

D201 resin and P507 extractant diluted with sulfonated kerosene were used to respectively separate vanadium and scandium, and impurity ions from hydrochloric acid leaching solution of red mud. More than 99% of vanadium was selectively adsorbed from the hydrochloric acid leaching solution under the conditions of pH value of 1.8, volume ratio of leaching solution to resin of 10, and flow rate of 3.

[Effect of moxibustion combined with autohemotherapy of acupoint injection for life quality of allergic rhinitis with deficiency of lung and spleen:a randomized controlled trial].

Objective: To observe the effects of moxibustion combined with autohemotherapy of acupoint injection and simple moxibustion for allergic rhinitis(AR) with deficiency of lung and spleen and to explore its mechanism.

Methods: By random number table,75 patients who matched the criteria were assigned into a moxibustion combined with autohemotherapy of acupoint injection group(a combination group,37 cases) and a moxibustion group(38 cases). In the combination group,moxibustion was used at bilateral Yingxiang(LI 20) and injection bila-teral Feishu(BL 13),Pishu(BL 20) and Zusanli(ST 36).

[Effect of different frequency electroacupuncture on the expression of substance P and beta-endorphin in the hypothalamus in rats with gastric distension-induced pain].

Objective: To observe the effect of different frequency electroacupuncture (EA) on hippocampal substance P (SP) and beta-endorphin (beta-EP) in rats with gastralgia so as to explore its underlying mechanism in preventing and relieving visceral pain.

Method: Fifty rats were randomly divided into control, sham operation, model, low- frequency-EA and high frequency-EA groups. Gastralgia model was duplicated by gastric distension (a pressure of 40 mmHg) with a latex balloon.