[Effect of moxibustion combined with autohemotherapy of acupoint injection for life quality of allergic rhinitis with deficiency of lung and spleen:a randomized controlled trial].

Objective: To observe the effects of moxibustion combined with autohemotherapy of acupoint injection and simple moxibustion for allergic rhinitis(AR) with deficiency of lung and spleen and to explore its mechanism.

Methods: By random number table,75 patients who matched the criteria were assigned into a moxibustion combined with autohemotherapy of acupoint injection group(a combination group,37 cases) and a moxibustion group(38 cases). In the combination group,moxibustion was used at bilateral Yingxiang(LI 20) and injection bila-teral Feishu(BL 13),Pishu(BL 20) and Zusanli(ST 36). In the moxibustion group,moxibustion was applied bilaterally at all the above acupoints. Acupoint injection was given twice a week,and moxibustion once a day,seven days as a course. The patients were observed for four courses and followed up half a year after treatment. Rhinoconjunctivitis quality of life questionnaire(RQLQ) was compared before and after treatment and at follow-up. The short-term and long-term effects as well as the changes of interferon-(IFN-),interleukin-4(IL-4) and immunoglobulin E(IgE) were observed in the two group.

Results: After treatment,the obviously effective rate of the combination group was 75.68%(28/37),which was higher than 52.63%(20/38) of the moxibustion group(<0.05). But at follow-up, the obviously effective rate of the moxibustion group was 47.37%(18/38),which was better than 24.32%(9/37) of the combination group(<0.05). Life quality of the two group in all aspects after treatment and at follow-up were apparently improved compared with the baseline(<0.01,<0.05). After treatment,the life quality,sleep condition,non nasal-eye symptoms,behavior issue of the combination group were superior to those of the moxibustion group(all <0.05),and at follow-up,the above outcomes,the eye and nasal symptoms as well as emotional response of the mo-xibustion group were better(all <0.05). There was statistical significance in the two group about serum IFN-,IgE,IL-4 before and after treatment(<0.01,<0.05),and significance existed between the two groups(<0.05).

Conclusions: Moxibustion combined with autohemotherapy of acupoint injection can effectively improve the short-term quality of life of AR with deficiency of lung and spleen. The mechanism may be related to balancing the immune response of Th1 and Th2.