The Shift Toward Outpatient Care in India: Evidence From National Health Surveys, 2014 and 2017-18.

This article explores reasons for the shift toward outpatient care in India between 2014 and 2017-18. The study used the most recent unit-level data from health surveys conducted by the National Sample Survey for the years 2017-18 and 2014. It is based on the uniform 15-day recall period for utilization of inpatient and outpatient care.

Natural variation of the wheat root exudate metabolome and its influence on biological nitrification inhibition activity.

Excessive nitrogen use and low nitrogen use efficiency (NUE) in current agroecosystems are disrupting the global nitrogen cycle. Chemical inhibitors offer only temporary relief, while plant-derived biological nitrification inhibitors (BNIs) remain safer but underexplored. Identifying biological nitrification inhibition (BNI) traits in nitrogen-demanding crops like wheat is key to improving sustainability.

National Consensus Statement on Role of Bisoprolol across Cardiovascular Continuum: Special Focus on Women.

Cardiovascular diseases (CVDs) represent a significant health concern worldwide, with women facing distinct challenges in the prevention, diagnosis, and management of these conditions. In India, hypertension is a prevalent cardiovascular (CV) risk factor, affecting nearly one-third of adults, and women experience a disproportionately high burden across all age-groups. The CV continuum, which spans from risk factors to CV events and ultimately to heart failure (HF), demonstrates how the progression of CVD impacts women at each stage differently due to gender-specific mechanisms like hormonal influences, pregnancy complications and the effects of menopause.

Chemistry beyond the scale of exact diagonalization on a quantum-centric supercomputer.

A universal quantum computer can simulate diverse quantum systems, with electronic structure for chemistry offering challenging problems for practical use cases around the hundred-qubit mark. Although current quantum processors have reached this size, deep circuits and a large number of measurements lead to prohibitive runtimes for quantum computers in isolation. Here, we demonstrate the use of classical distributed computing to offload all but an intrinsically quantum component of a workflow for electronic structure simulations.

Editing cis-elements of OsPHO1;2 improved phosphate transport and yield in rice.

Increasing grain yield is the primary goal of crop improvement, which is globally affected by the low availability of soil phosphate (Pi). Overexpressing Pi transporters to enhance Pi uptake often results in Pi toxicity and growth retardation. Despite advances in genetic engineering, targeting the cis-regulatory motifs of Pi transporters remains underexplored for understanding plant mechanisms and improving Pi status.

Molecular docking and molecular dynamics simulation studies of thiazole-coumarin and thiazole-triazole conjugates against M and ACE2 receptor for SARS COV-2.

The recent COVID-19 pandemic, which caused severe respiratory infections and multiple organ failure leading to death, has drawn the attention of researchers around the world. Several vaccines are available for protection against SARS-CoV-2. However, the frequent changes in its viral genome have raised concerns about the efficacy of current vaccines.

Multivariate decomposition of shift toward public facilities for inpatient care in rural India: evidence from National Sample Survey.

Introduction: Public facilities in health systems are essential for improving access and ensuring equity. Public facility utilization for inpatient care in rural areas increased between the most recent National Sample Survey (NSS) health rounds of 2014 and 2017-2018. This study conducted a decomposition analysis to identify the underlying causes that contributed to this increase in public facility utilization.

Competitive Host-Guest and Guest-Guest Interaction Dependent Flexibility of Crystal-Size-Engineered ZIF-8: An Inelastic Neutron Scattering Study.

Metal-organic frameworks (MOFs) exhibit remarkable structural flexibility, influenced by factors such as crystal size and guest molecule interactions. Here, we investigate the crystal-size-dependent flexibility of ZIF-8 by using inelastic neutron scattering (INS). Our study provides direct experimental evidence of reduced flexibility in small ZIF-8 crystals, underscoring the importance of crystal-size-engineering in modulating MOF properties.

Transcriptional response of cultivated peanut (Arachis hypogaea L.) roots to salt stress and the role of DNA methylation.

Our study unravels a complex multi-layered molecular response of peanut roots to salinity, where reprograming of gene-expression is partly executed by changes in methylome via RdDM pathway and exerted through transcription factors. Peanut (Arachis hypogaea L.) is a major oilseed crop of global importance, whose production is severely impacted by salinity.

Intelligent health model for medical imaging to guide laymen using neural cellular automata.

A layman in health systems is a person who doesn't have any knowledge about health data i.e., X-ray, MRI, CT scan, and health examination reports, etc.

Correlation between free volume structure and ionic conductivity of a poly(ethylene oxide) and dendritic fibrous nanosilica composite-based electrolyte: an investigation using positron annihilation and broadband dielectric spectroscopy.

Passive and active filler-loaded poly(ethylene oxide) (PEO)-based solid-state polymer electrolytes (SPEs) are considered promising alternatives to currently used flammable liquid electrolytes in lithium metal batteries. The enhancement in the ionic conductivity of PEO-based composite electrolytes is attributed to additional ion conduction pathways available at the interphase region. Considering this aspect, in the present study, we prepared dendritic fibrous nanosilica (DFNS)-loaded PEO-based polymer composite (PEO-DNFS), and electrolytes (PEO-Li, PEO-Li-DFNS) with an EO : Li ratio of 20 : 1.

Regulation of CO Pressure-Induced Flexibility of Zeolitic Imidazolate Framework-7 Using a Mixed Linker Strategy: An In Situ Positron Annihilation Spectroscopy Study.

The external stimuli-induced framework flexibility of zeolitic imidazolate frameworks (ZIFs) is a fascinating physical phenomenon. Flexible ZIFs offer varying pore aperture under gas pressures leading to inferior separation selectivity because the flexibility-induced enlargement in the aperture size allows diffusion of larger size gas molecules. Desolvated ZIF-7 crystals show high flexibility and phase transformation from the narrow pore () to the open pore () phase under CO pressure.

Structural-functional relevance of DNAJBs in protein aggregation and associated neurodegenerative diseases.

DNAJ proteins, also known as HSP40s, are co-chaperones that regulate the multifunctionality of HSP70s in maintaining cellular protein homeostasis. The heterogeneous family of DNAJ co-chaperones is classified into three classes (A, B and C), where structural diversity within the class defines their specific functions. Among three classes, the DNAJB class of co-chaperones are associated with cellular compartment-specific protein folding, disaggregation and degradation of proteins and enables effective targeting of a broad spectrum of aggregation-prone substrate proteins.

Understanding the Mechanism and Ascertaining the Sorption Sites for the Highly Efficient and Selective Sorption of U(VI) and Th(IV) by Graphene/Zeolitic Imidazolate Framework-90 Composites: An Experimental and Theoretical Approach.

Efficient removal of radionuclides from aqueous solutions is of utmost importance for public and environmental safety. The development of efficient adsorbents and a deeper understanding of the adsorption mechanism of radionuclides are crucial for designing superior adsorbents. In view of this, the present investigation deals with the understanding of the highly efficient sorption of U(VI) and Th(IV) from an aqueous acidic feed using a multilayer graphene/Zeolitic Imidazolate Framework-90 (ZIF-90G) composite.

Optical control of levitated nanoparticles via dipole-dipole interaction.

We propose a scheme to create and unidirectionally transport thermal squeezed states and random-phase coherent states in a system of two interacting levitated nanoparticles. In this coupled levitated system, we create a thermal squeezed state of motion in one of the nanoparticles by parametrically driving it and then transporting the state to the other nanoparticle by making use of a unidirectional transport mechanism. This mechanism is based on inducing a nonreciprocal type of coupling in the system by suitably modulating the phases of the trapping lasers and the interparticle distance between the levitated nanoparticles.

Ocimum tenuiflorum leaf-mediated graphitic carbon nitride and ZnO/GCN nanohybrid: a sustainable approach for environmental applications.

Water contamination is a real concern, and safe water demand increases with the growing world population. The development of eco-friendly and cost-effective technologies that can clean water is necessary. This study investigates the bio-synthesis of pure graphitic carbon nitride nanoparticles (GCN-NPs), zinc oxide nanoparticles (ZnO-NPs), and ZnO-doped graphitic carbon nitride nanohybrids (ZnO/GCN-NHs) using Ocimum tenuiflorum (OT) leaf extract, with a focus on their potential applications in wastewater treatment, cytotoxicity assessment, and antibacterial activity.

Modulating Leaching of Mesosulfuron Methyl, Iodosulfuron Methyl and Transformation Products: Effects of Rainfall Intensity, Flow Patterns and Organic Amendments.

In light of the environmental pollution risks, the effect of rainfall and flow conditions and addition of farmyard manure on leaching potential of mesosulfuron, iodosulfuron methyl and their transformation products (TPs) was evaluated. Leaching was higher under 300 mm rainfall compared to 150 mm. Discontinuous flow conditions led to lower residues of the parent herbicides but higher concentrations of their TPs.