Multi-loci phylogeny reveals unexpected novelty of the complex (Thelephoraceae, Thelephorales) from China.

is a well-known species morphologically characterized by coralloid and leathery basidiomata with numerous fuscous purple to blackish-brown branches. It was once considered to exhibit a wide ecological range and distribution area. However, comprehensive phylogenetic analysis based on four loci (ITS, nrLSU, , and nrSSU) revealed that represents a species complex consisting of at least 12 cryptic taxa, with a biogeographic distribution pattern bounded by geographic regions: Asia, Eurasia, Europe, and North America.

Identifying psychological and clinical risk factors for moderate-to-severe tinnitus in older patients with hearing loss: a multivariable prediction model.

Objective: To develop and validate a clinical prediction model for moderate-to-severe tinnitus (THI ≥ 38) in patients with hearing loss and to identify the key psychological and clinical factors associated with its risk.

Methods: This retrospective single-centre study included 301 patients with hearing loss who visited Qinghai University Affiliated Hospital between August 2024 and May 2025. The cohort was randomly divided into a training set ( = 210) and a validation set ( = 91) in a 7:3 ratio.

S-ketamine exposure in early postnatal period induces social deficit mediated by excessive microglial synaptic pruning.

The impact of general anesthetics on neurodevelopment is highly controversial in terms of clinical and preclinical studies. Evidence mounted in recent years indicated development of social cognitions was more susceptible to general anesthesia in early life. However, the behavioral characterization during adolescence and underlying mechanisms remains unclear.

Bimetallic Phthalocyanine Monolayers as Promising Materials for Toxic HS, SO, and SOF Gas Detection: Insights from DFT Calculations.

The development of a high-performance gas sensor for the rapid and efficient detection of harmful SF decomposition gases (HS, SO, and SOF) is crucial for equipment environmental monitoring and safeguarding human health. In this work, first-principles calculations were conducted to assess the adsorption performance and sensing characteristics of these decomposition gases on two-dimensional metal-dimer-modified phthalocyanine (MnPc, TcPc, and MnTcPc) surfaces. The results demonstrate that the MnPc, TcPc, and MnTcPc monolayers possess enhanced structural stability.

New Contributions on Species Diversity of Genus and s.l. in China.

Southwest China is extremely rich in fungal resources, and a large number of new taxa have been discovered in recent years. In the present study, we examined 26 specimens of the genera and sensu lato, most of which were obtained in Yunnan Province. Through ITS-nrLSU- phylogenetic analysis, combined with morphological studies and geographic analyses, five new species were described, viz.

(, ), a new species from southwestern China.

(, ) is described as a novel species from Yunnan Province, southwestern China. It is morphologically recognised by a small basidiocarp with orange-yellow to orange-red scales on the pileus and stipe, white lamellae, orange-red to bright red basal mycelia, subglobose to broadly ellipsoid basidiospores with dense warts and short or long ridges. Phylogenetically analyses of DNA sequences from part of the 28S gene combined with the nuclear rDNA internal transcribed spacer (ITS) region also confirm that forms an independent lineage within subgenus section .

Four New Species and a New Combination of () from Subtropical and Tropical China.

Previous studies have shown that boletes are abundant and diverse in China, especially in tropical and subtropical regions. In the present study, morphological, ecological, host relationship, and a four-locus (28S, , , and ) molecular phylogenetic analyses were used to study the family in subtropical and tropical China. Four new bluing species are described from three genera, viz.

Single-cell transcriptomics reveals the pulmonary inflammation induced by inhalation of subway fine particles.

People generally take the subway and inevitably inhale the fine particles (PM) on subway platforms. This study revealed whether and how subway PM causes lung inflammation. Herein, the pulmonary inflammatory response to subway PM was observed in mice, manifesting as the inflammatory cells infiltration and collagen deposition in tissue, inflammatory cytokine enhancement in bronchoalveolar lavage fluid and Toll-like receptors signal pathway activation in the lungs.

Covalent organic frameworks with flexible side chains in hybrid PEMs enable highly efficient proton conductivity.

Electrochemical hydrogen compression (EHC) is an emerging energy conversion technology. Proton exchange membranes (PEMs) with high proton conductivity and high mechanical strength are highly required to meet the practical requirements of EHC. Herein, ionic covalent organic frameworks (iCOFs) with tunable side chains were synthesized and introduced into the sulfonated poly (ether ether ketone) (SPEEK) matrix to fabricate hybrid PEMs.

The Adsorption Mechanisms of SF-Decomposed Species on Tc- and Ru-Embedded Phthalocyanine Surfaces: A Density Functional Theory Study.

Designing high-performance materials for the detection or removal of toxic decomposition gases of sulfur hexafluoride is crucial for both environmental monitoring and human health preservation. Based on first-principles calculations, the adsorption performance and gas-sensing properties of unsubstituted phthalocyanine (HPc) and HPc doped with 4d transition metal atoms (TM = Tc and Ru) towards five characteristic decomposition components (HF, HS, SO, SOF, and SOF) were simulated. The findings indicate that both the TcPc and RuPc monolayers are thermodynamically and dynamically stable.

Four cases of reported adverse effects from black boletoi, Anthracoporus nigropurpureus (Boletaceae) mushroom ingestion.

In southwestern China, wild boletes are generally considered as safe and tasty edible mushrooms. However, in fact, significant adverse effects after ingestion of boletes is commonly reported in this region. In June 2022, four cases occurred in central and southwestern of China.

Inhalation of subway fine particles induces murine extrapulmonary organs damage.

Because of its speed and convenience, the subway has become the first choice for travel by many residents. However, the concentration of fine particles (PM) in the air of a subway platform is higher than that of the ground level or carriage. Moreover, the composition and source of subway PM differ from those of atmospheric PM.

Intratracheally administered iron oxide nanoparticles induced murine lung inflammation depending on T cells and B cells.

Iron oxide nanoparticles (FeO NPs), produced in track traffic system and a wide range of industrial production, poses a great threat to human health. However, there is little research about the mechanism of FeO NPs toxicity on respiratory system. Rag1 mice which lack functional T and B cells were intratracheally challenged with FeO NPs, and interleukin (IL)-33 as an activator of group 2 innate lymphoid cells (ILC2s) to observe ILC2s changes.

Optical Fiber-Based Recording of Climbing Fiber Ca Signals in Freely Behaving Mice.

The olivocerebellar circuitry is important to convey both motor and non-motor information from the inferior olive (IO) to the cerebellar cortex. Several methods are currently established to observe the dynamics of the olivocerebellar circuitry, largely by recording the complex spike activity of cerebellar Purkinje cells; however, these techniques can be technically challenging to apply in vivo and are not always possible in freely behaving animals. Here, we developed a method for the direct, accessible, and robust recording of climbing fiber (CF) Ca signals based on optical fiber photometry.

Acute iron oxide nanoparticles exposure induced murine eosinophilic airway inflammation via TLR2 and TLR4 signaling.

Iron oxide nanoparticles (Fe O NPs) is the main component of air pollution particles in urban rail transit environment. People are more exposed to Fe O NPs, however, the studies on relationship between Fe O NPs and respiratory health are limited. In the present study, acute airway inflammation caused by Fe O NPs and its possible mechanism were investigated.

New and noteworthy boletes from subtropical and tropical China.

The morphology, ecology, and phylogenetic relationships of specimens of the family Boletaceae from subtropical and tropical China were investigated. Four species, , , , and , are new to science. and are redescribed.

The genus Heimioporus in China.

Species of Heimioporus (Boletaceae, Boletales) in China are investigated on the basis of morphology and molecular phylogenetic analyses of DNA sequences from the nuc rDNA internal transcribed spacer ITS1-5.8S-ITS2 region and nuc 28S rDNA D1-D2 domains (28S) and translation elongation factor 1-α gene (TEF1). Three species are recognized in China: H.