Cases of Lungworm in Cats from Southern Poland in the Autopsy and Cytological Material.

Lungworms in carnivorous domestic animals are infestations that are relatively uncommon. However, in felines, especially wild ones, they are not at all rare. This study aimed to assess the prevalence of respiratory parasite infections (lung nematodes) in domestic cats based on necropsy and cytological examinations and to highlight the cytological examination of respiratory material as a practical and straightforward diagnostic method.

Molecular Cardiac Changes in Feline Hyperthyroidism and Hypertrophic Cardiomyopathy: Focus on Desmin, Calreticulin, and Interleukin-10 Expression.

Feline hyperthyroidism is the most frequent endocrinopathy in adult and senior cats, frequently leading to cardiac changes characterised by a hypertrophic cardiomyopathy (HCM) phenotype, which may partially reverse with appropriate treatment. However, the structural and molecular alterations in the myocardium can persist and closely resemble those observed in hypertrophic cardiomyopathy. Despite this clinical overlap, protein expression patterns in the hearts of hyperthyroid cats remain poorly understood.

Immunohistochemical expression of testin protein in testicular tumours in dogs.

Testin (TES), a protein localised in the cytoplasm and belonging to the LIM family of proteins, is part of the cytoskeleton localised along stress fibres and recruited to focal adhesions. It is considered a tumour suppressor protein in humans and decreased TES expression has been shown to increase cell motility and decrease cell-cell contact. In veterinary medicine, TES has only been studied in rat testes and, more recently, also in canine testes.

The Pathological and Histopathological Findings in Cats with Clinically Recognised Hypertrophic Cardiomyopathy Are Related to the Severity of Clinical Signs and Disease Duration.

Hypertrophic cardiomyopathy (HCM) is the most frequent type of cardiac disease in cats. Due to its high prevalence and risk of sudden and severe signs, the disease is an important topic of various research. Despite the focus on the clinical course of the disease, studies presenting the pathological and histopathological patterns are rare.

A probable case of "lumpy jaw" in early medieval (11th - 12th c.) cattle from a stronghold in Kruszwica, Poland.

Objective: The purpose of this article is to try to determine the probable cause of the disease from which the study animal suffered.

Materials: The skeletal material included a caudal fragment of a cattle mandible. The specimen, exhibiting chronic disease was separated from approximately 10,000 early medieval cattle remains discovered during excavations of the former Kruszwica stronghold.

Study on the expression of testin in the testes of dogs.

Introduction: Testin is a protein involved in cell mobility, adhesion and colony formation. In rats, testin presence has been reported in the testes, and its possible role in spermatogenesis has been suggested. Studies in humans also suggest a possible role of testin as a cancer suppressor protein.

Canine urothelial carcinoma: expression of Periostin in spontaneous canine urothelial carcinoma and its correlation with histological features.

The tumor microenvironment is considered one of the main players in cancer development and progression and may influence the behavior of cancer cells. Periostin (POSTN) is an extracellular matrix protein, and its main functions are induction of fibrillogenesis, fibroblastic cell proliferation and migration, enhancing regeneration in normal tissue, and promoting metastasis in case of neoplasia. POSTN has already been studied in humans in several normal tissues, inflammatory processes, and neoplasms, revealing an important role in tumor progression in various types of cancer, such as colon, lung, head and neck, breast, ovarian, and prostate.

Prevalence of Tumours and Tumour-like Lesions in Domestic and Exotic Animals from Lower Silesia and its Surrounds in Poland in 2014-2017.

Introduction: An analysis of samples originating from domestic and exotic animals from Lower Silesia but also from other parts of Poland was carried out based on research conducted in 2014-2017.

Material And Methods: The materials used for the study were 11,338 tumour samples taken during surgery and as biopsies and posthumously during necropsies. They were sent to the Department of Pathology at Wrocław University of Environmental and Life Sciences for histopathological diagnosis.

Tracheal Hemangioma Causing Lung Emphysema and Pneumopericardium in a Rabbit-A Case Report.

A pet rabbit (female, 8 years old, and mixed breed) with symptoms of dyspnea, apathy, and weight loss was treated for an acute respiratory infection. Due to the lack of improvement, it was referred to the Imaging Diagnostics Laboratory of the Department and Clinic of Surgery for a computer tomography scan of the thoracic cavity. The examination revealed the presence of air in the pericardial sac, a pneumopericardium, along with pulmonary emphysema.

Simultaneous poisoning of 48 birds of prey - bendiocarb determination with the use of UHPLC-ESI-MS/MS method in fatal case from Eastern Europe.

Aim: Bendiocarb is used against a wide range of insects but has already been withdrawn from the market in some countries. It poses a high risk to birds as they can accidentally ingest it while searching for food, followed by toxic effects. This paper presents the results of toxicological and histopathological studies of 48 cases of intentional birds of prey poisoning with bendiocarb in Eastern Europe, specifically Poland.

Case report laparoscopy-assisted pre-pubic urethrostomy as a palliative procedure for resection of distal urethral tumor in a female dog.

Background: This paper presents the first described case of laparoscopy-assisted prepubic urethrostomy and laparoscopic resection of a tumor of the distal part of the urethra in a female dog as a palliative treatment.

Case Presentation: An intact, 11 -year-old, mixed breed female dog, weighing 15 kg, was admitted with signs of urinary obstruction and difficulty with catheterization. Vaginal, rectal, and endoscopic examinations revealed a firm mass in the pelvic cavity at the level of the pelvic urethra.

Urothelial cancer of the prostate gland. Immunohistochemical analysis of two cases of rare canine cancer.

Introduction: The study aimed to diagnose urothelial cancer of prostate gland (UCPG) in dogs as the primary focus and in its metastasis based on the expression of specific proteins used in immunohistochemical diagnosis of prostate cancer in men.

Material And Methods: The study was carried out on specimens collected during a post-mortem examination from macroscopic lesions of the prostate glands from two dogs. The immunoexpression of the following proteins was verified: prostate-specific antigen (PSA), high molecular weight cytokeratins (HMWCK), cytokeratin 7 and 20 (CK-7,-20), E-cadherin, von Willebrand factor, cyclooxygenase-2 (COX-2), microsomal PGE2-1 synthase (mPGES-1) and component of the minichromosome 7 maintenance complex (MCM7).

Expression of Periostin in Mammary Cancer Cells of Female Dogs.

Background/aim: Periostin (POSTN) has a significant role in proliferation and migration of tumour cells as well as tumour progression. This study aimed to determinate POSTN expression in cancer cells in malignant and benign tumours of the mammary gland in female dogs.

Materials And Methods: All together 83 cancers, 24 adenomas and 7 unchanged fragments of the mammary glands of bitches were investigated.

A modified Sydney system for the diagnosis of chronic gastritis in dogs.

Background: The Sydney system for assessing inflammatory lesions in the gastric mucosa is based on endoscopic and histological examinations. This study aimed to apply the Sydney system to diagnose gastritis in dogs. The study also compared the results of endoscopic and histological examinations conducted on gastric mucosal biopsy specimens.

Does open ovarian biopsy in prepubertal age affect ovarian reserve in a rat model?

Background: Partial resection of the ovary carries a possible risk of fertility reduction. We studied the influence of open ovarian biopsy on ovarian reserve, including anti-Müllerian hormone and follicle-stimulating hormone serum level evaluation, in a prepubertal rat model.

Methods: Interventions - the initial surgery was unilateral ovarian biopsy (38 rats, group B1, B2) or unilateral ovarian biopsy and ovarian resection of the contralateral gonad (38 rats, group BR1, BR2).

Expression of Periostin in Cancer-associated Fibroblasts in Mammary Cancer in Female Dogs.

Background/aim: Mammary neoplasms, like breast neoplasms in women, are one of the most common tumours in female dogs. Cancer-associated fibroblasts (CAFs) found in the tumour stroma play a role in angiogenesis and increase cell migration, contributing to tumour growth and progression, as well as metastasis. The aim of our work was to determine the level of periostin (POSTN) expression in CAFs in mammary tumours of female dogs.

Expression of Podoplanin in Mammary Cancers in Female Dogs.

Background/aim: Mammary neoplasms are very common tumours in female dogs. Cancer-associated fibroblasts (CAFs) play an important role in the oncogenesis process. One of the useful proteins used in the diagnostics of CAFs cells is podoplanin (PDPN).

Fatal pulmonary hemorrhage in a horse during bronchoalveolar lavage - single case report.

Background: Pulmonary hemorrhage is a rare cause of death in horses. Hemorrhage within the respiratory tract has many causes, including mycosis of the guttural pouch, invasive procedures causing serious trauma to nasal conchae, or lung biopsy. We report on a rare case of a fatal pulmonary hemorrhage in a horse after a severe cough during bronchoalveolar lavage.

Identification of probable telangiectatic osteosarcoma from a dog skull from multicultural settlement Polwica-Skrzypnik in Lower Silesia, Poland.

This report presents canid cranial skeletal pathology from an excavation associated with the Przeworsk culture (III c. BC - V c. AD).

Cardiomyocyte marker expression in dogs with left atrial enlargement due to dilated cardiomyopathy or myxomatous mitral valve disease.

Introduction: Dilated cardiomyopathy (DCM) and myxomatous mitral valve disease (MMVD) are common heart conditions in dogs. They have different etiology and pathogenesis and although other studies focused on changes in the left ventricles of the affected hearts, the aim of our study was to assess the expressions of some intrinsic proteins in the enlarged left atria.

Material And Methods: We performed an immunohistochemical analysis of left atrial specimens obtained from 15 dogs with DCM, 35 dogs with MMVD and six control dogs.

The immunohistochemical evaluation of selected markers in the left atrium of dogs with end-stage dilated cardiomyopathy and myxomatous mitral valve disease - a preliminary study.

Background: Dilated cardiomyopathy (DCM) and myxomatous mitral valve disease (MMVD) are the most common diseases noted in dogs. Although their pathogenesis varies, both include a significant enlargement of the left atrium. The study was carried out on left atrial specimens obtained from 56 dogs, including those from 34 dogs with clinically diagnosed MMVD, 15 dogs with DCM and 7 dogs without heart disease (control group).

Epidemiological and pathological features of primary cardiac tumours in dogs from Poland in 1970-2014.

Primary heart tumours affect less than 1% of dogs. Due to their rare incidence, every research showing the frequency of cardiac tumours is valuable. Routine diagnostics is often complemented with immunohistochemical analysis.

A comparison of the histopathologic pattern of the left atrium in canine dilated cardiomyopathy and chronic mitral valve disease.

Background: Dilated cardiomyopathy (DCM) and chronic mitral valve disease (CMVD) in dogs are associated with heart chamber enlargement, also of the left atrium. DCM is often accompanied by rhythm disturbances (mainly atrial fibrillation or ventricular arrhythmias). In CMVD, arrhythmias are observed less frequently.

Useful immunohistochemical indicators in canine mast cell tumours.

Morphological and immunohistochemical analysis of 45 canine mast cell tumours was performed to determine whether the proteins examined are useful for a more precise description of tumour morphology and a more reliable determination of the prognosis in patients. Tissue sections were stained according to the standard haematoxylin and eosin (HE) technique and with toluidine blue to demonstrate cytoplasmic granules. Immunohistochemical studies were performed, using the cell markers CD117 (c-kit), p16 and von Willebrand factor (FVIII).