Expression of Periostin in Mammary Cancer Cells of Female Dogs.

Background/aim: Periostin (POSTN) has a significant role in proliferation and migration of tumour cells as well as tumour progression. This study aimed to determinate POSTN expression in cancer cells in malignant and benign tumours of the mammary gland in female dogs.

Materials And Methods: All together 83 cancers, 24 adenomas and 7 unchanged fragments of the mammary glands of bitches were investigated.

Expression of Periostin in Cancer-associated Fibroblasts in Mammary Cancer in Female Dogs.

Background/aim: Mammary neoplasms, like breast neoplasms in women, are one of the most common tumours in female dogs. Cancer-associated fibroblasts (CAFs) found in the tumour stroma play a role in angiogenesis and increase cell migration, contributing to tumour growth and progression, as well as metastasis. The aim of our work was to determine the level of periostin (POSTN) expression in CAFs in mammary tumours of female dogs.

Expression of Podoplanin in Mammary Cancers in Female Dogs.

Background/aim: Mammary neoplasms are very common tumours in female dogs. Cancer-associated fibroblasts (CAFs) play an important role in the oncogenesis process. One of the useful proteins used in the diagnostics of CAFs cells is podoplanin (PDPN).