Apical-out bovine intestinal organoids as an infection model for .

is a major pathogen responsible for neonatal calf diarrhoea, but research has been hampered due to the lack of models that can complete the life cycle. In this scenario, human and murine small intestinal organoids (enteroids) are emerging as new tools. However, models employing bovine cells, relevant for the pathogenesis in the target species, are lacking.

Rapid review: Recent advances in models for the study of .

research has been hampered by the lack of models that can recapitulate the life cycle of the parasite, thus relying on repeated animal infections. Traditional systems, employing cancerous cell lines, have been unable to support sexual reproduction, but have been widely employed for drug screening assays and allowed transcriptome mapping of the parasite, but extrapolation of those results to infections is limited. In recent years, intestinal organoids (enteroids), grown as 3D structures, have come to be recognized as more physiologically relevant, complex systems, since they more accurately reproduce the cell populations present in the small intestine.

From the field: a cryptosporidiosis outbreak among veterinary students associated with activities during the lambing period in Norway during 2024.

A recent outbreak of cryptosporidiosis (, subtype IIdA23G1) among veterinary students associated with extracurricular activities concerned with lambs is described from Norway. Although cryptosporidiosis outbreaks among veterinary students have been frequently reported, this is among the first from lamb contact. oocysts were detected in samples from two students and three lambs.

Fatal pulmonary hemorrhage in a horse during bronchoalveolar lavage - single case report.

Background: Pulmonary hemorrhage is a rare cause of death in horses. Hemorrhage within the respiratory tract has many causes, including mycosis of the guttural pouch, invasive procedures causing serious trauma to nasal conchae, or lung biopsy. We report on a rare case of a fatal pulmonary hemorrhage in a horse after a severe cough during bronchoalveolar lavage.

The effect of single pretreatment with salbutamol on recovery of bronchoalveolar lavage fluid in horses with suspected or confirmed severe equine asthma.

Background: Bronchoalveolar lavage (BAL) is a method for the recovery of respiratory secretion from the lower airways.

Objectives: To investigate if the administration of a single dose of a bronchodilatator in horses with a suspected or confirmed severe equine asthma could improve recovery of bronchoalveolar lavage fluid (BALF).

Animals: Twenty-eight horses with severe equine asthma.