Correction: Evaluating multiple large language models on orbital diseases.

[This corrects the article DOI: 10.3389/fcell.2025.

Harnessing bio-modified coal gangue for mine wastewater remediation: a sustainable approach.

Mine wastewater pollution, primarily caused by heavy metals and sulfates, poses a significant threat to ecosystems and water quality in mining-affected regions. Effective remediation is essential for mitigating these environmental impacts and ensuring sustainable water management. This study explores the potential of bio-modified coal gangue (MCG) as a sustainable solution for remediating mine wastewater.

Reproducibility assessment of magnetic resonance spectroscopy of pregenual anterior cingulate cortex across sessions and vendors via the cloud computing platform CloudBrain-MRS.

Proton magnetic resonance spectroscopy (H-MRS) has potential in clinical diagnosis and understanding the mechanism of illnesses. However, its application is limited by the lack of standardization in data acquisition and processing across time points and between different magnetic resonance imaging (MRI) system vendors. This study examines whether metabolite concentrations obtained from different sessions, scanner models, and vendors can be reliably reproduced and combined for diagnostic analysis-an important consideration for rare disease research.

Evaluating multiple large language models on orbital diseases.

The avoidance of mistakes by humans is achieved through continuous learning, error correction, and experience accumulation. This process is known to be both time-consuming and laborious, often involving numerous detours. In order to assist humans in their learning endeavors, ChatGPT (Generative Pre-trained Transformer) has been developed as a collection of large language models (LLMs) capable of generating responses that resemble human-like answers to a wide range of problems.

Characterization of three novel members of genus from in the Qinghai-Tibet Plateau: description of sp. nov., sp. nov. and sp. nov.

Six aerobic, Gram-stain-positive, non-motile, rod-shaped bacterial strains (P13, P18, P16, P17, P20 and P15) were isolated from the intestinal contents of the plateau vole () collected from the Qinghai-Tibet Plateau, PR China. Phylogenetic analyses showed that these isolates formed three well-separated lineages in all phylogenetic and phylogenomic trees comprising members of the genus . The average nucleotide identity and digital DNA-DNA hybridization values between the three novel type strains (P13/P16/P20) and other known species in this genus were all below the thresholds of 95-96% and 70%.

Physics-informed neural networks for denoising high b-value diffusion-weighted images.

Diffusion-weighted imaging (DWI) is widely applied in tumor diagnosis by measuring the diffusion of water molecules. To increase the sensitivity to tumor identification, faithful high b-value DWI images are expected by setting a stronger strength of gradient field in magnetic resonance imaging (MRI). However, high b-value DWI images are heavily affected by reduced signal-to-noise ratio due to the exponential decay of signal intensity.

Retinal microvasculature alteration in patients with acute pancreatitis: an observational OCTA study.

Objective: To evaluate changes in retinal layer thickness and microvascular density in pancreatitis patients using optical coherence tomography angiography (OCTA).

Methods: The study involved 16 pancreatitis patients and 16 healthy controls. Each participant underwent a superficial OCTA scan, with images divided into nine subregions to compare macular retinal thickness (RT) and superficial vascular density (SVD) between groups.

Inhibition of colorectal carcinogenesis by sunitinib malate: disruption of the IL-6/STAT3/c-MYC/TWIST/MMP2 autocrine signaling axis.

Sunitinib, a multi-targeted receptor tyrosine kinase inhibitor with specificity for VEGFR, KIT, FLT3, and PDGFR, has demonstrated clinical efficacy as a first- to third-line treatment for refractory renal carcinoma. Our previous research indicated that sunitinib malate suppresses intestinal polyp proliferation by downregulating IL-6 mRNA expression, suggesting a potential analogous mechanism in colorectal carcinoma inhibition. This study aimed to elucidate the pharmacological effects and molecular mechanisms of sunitinib malate on colorectal carcinoma using HCT116, RKO, HT29, and SW480 cell lines in vitro and HCT116-derived xenografts in nude mice in vivo.

Relationship between adolescent gaming addiction and myopia, ocular surface condition, and health status: a questionnaire based cohort study.

This study explores the relationship between gaming addiction among Chinese adolescents and their myopia, ocular surface conditions, and overall health. A cross-sectional questionnaire-based cohort study included 835 participants aged 13-17, selected from 3300. Tools included the Hospital Anxiety and Depression Scale (HADS), Van Dream Anxiety Scale (VDAS), 36-Item Short-Form Health Survey (SF-36), Ocular Surface Disease Index (OSDI), Internet Addiction Test (IAT), and Internet Gaming Disorder Scale-20 (IGD-20).

Single-State Multi-Party Quantum Key Agreement with Single-Particle Measurement.

In this study, we propose a single-state multi-party quantum key agreement (MQKA) protocol with single-particle measurement. Firstly, a single-state three-party quantum key agreement protocol with single-particle measurement is introduced, followed by a security analysis that validated its capability to resist potential internal and external attacks. Furthermore, we utilize multi-particle entangled states to present a multi-party version of the single-state multi-party quantum key agreement with single-particle measurement.

Topical Application of VitB6 Ameliorates PM2.5-Induced Dry Eye via NFκB Pathway in a Murine Model.

Dry eye (DE) is mainly characterized by dryness, foreign body sensation, eye pain and visual impairment. Their possible causes are mainly inflammation, tissue damage and neurosensory abnormalities, and vitamin B6 (VitB6) attenuates the inflammatory response by modulating the NF-κB pathway to quench reactive oxygen species (ROS). The aim of this experiment was to investigate the therapeutic effect of VitB6 eye drops on particulate matter 2.

Dynamic changes of spontaneous brain activity in patients after LASIK: a resting-state fMRI study.

Aim: To investigate changes in local brain activity after laser assisted keratomileusis (LASIK) in myopia patients, and further explore whether post-LASIK (POL) patients and healthy controls (HCs) can be distinguished by differences in dynamic amplitude of low-frequency fluctuations (dALFF) in specific brain regions.

Methods: The resting-state functional magnetic resonance imaging (rs-fMRI) data were collected from 15 myopic patients who underwent LASIK and 15 matched healthy controls. This method was selected to calculate the corresponding dALFF values of each participant, to compare dALFF between the groups and to determine whether dALFF distinguishes reliably between myopic patients after LASIK and HCs using the linear support vector machine (SVM) permutation test (5000 repetitions).

Central alterations of brain networks in patients with optic neuritis: a resting state fMRI study.

Aim: To assess the alterations in the resting-state function connections between the two cerebral hemispheres in patients with optic neuritis (ON) and healthy controls (HCs).

Methods: A total of 12 ON patients (six males and six females) and 12 HCs (six males and six females) who were highly matched for sex, age, and educational level were recruited. They underwent functional magnetic resonance imaging (fMRI), testing and brain activities were assessed using the degree centrality (DC) method.

Changes in retinal capillary density in female with type 2 diabetes and gestational diabetes-an analysis based on OCTA technology.

Aim: To evaluate alterations in conjunctival vascular density (CVD) and macular capillary density (MCD) in female patients with type 2 diabetes mellitus (T2DM) and gestational diabetes mellitus (GDM) using optical coherence tomography angiography (OCTA).

Methods: A total of 60 female participants were recruited, comprising 20 patients with T2DM, 20 patients with GDM, and 20 healthy age-matched controls (HCs). OCTA was used to assess superficial and deep retinal and conjunctival capillary plexuses.

Alterations of interhemispheric functional connectivity in patients with hypertensive retinopathy using voxel-mirrored homotopic connectivity: a resting state fMRI study.

Aim: To analyze whether alterations of voxel mirror homology connectivity (VMHC) values, as determined by resting-state functional magnetic resonance imaging (rs-fMRI), occur in cerebral regions of patients with hypertensive retinopathy (HR) and to determine the relationship between VMHC values and clinical characteristics in patients with HR.

Methods: Twenty-one patients with HR and 21 age-matched healthy controls (HCs) were assessed by rs-fMRI scanning. The functional connectivity between the hemispheres of the cerebrum was assessed by measuring VMHC, with the ability of VMHC to distinguish between the HR and HC groups assessed using receiver operating characteristic (ROC) curve analysis.

Brain activity in different brain areas of patients with diabetic vitreous hemorrhage according to voxel-based morphometry.

Aim: To elucidate the neuropathological mechanisms underlying diabetic vitreous hemorrhage (DVH) and its correlation with clinical characteristics.

Methods: Twenty-one individuals with DVH (male/female 12/9; mean age 52.29±11.

The amplitude of low frequency fluctuation and spontaneous brain activity alterations in age-related macular degeneration.

Background: Wet age-related macular degeneration (wAMD) is a vision-threatening eye disease worldwide. The amplitude of low-frequency fluctuation (ALFF) method was used to observe changes in spontaneous brain activity, which may help to investigate the underlying pathological mechanism of AMD.

Methods: Eighteen patients with wAMD and 18 age- and gender-matched healthy controls (HCs) were recruited.

In Vivo Confocal Microscopy for Automated Detection of Meibomian Gland Dysfunction: A Study Based on Deep Convolutional Neural Networks.

The objectives of this study are to construct a deep convolutional neural network (DCNN) model to diagnose and classify meibomian gland dysfunction (MGD) based on the in vivo confocal microscope (IVCM) images and to evaluate the performance of the DCNN model and its auxiliary significance for clinical diagnosis and treatment. We extracted 6643 IVCM images from the three hospitals' IVCM database as the training set for the DCNN model and 1661 IVCM images from the other two hospitals' IVCM database as the test set to examine the performance of the model. Construction of the DCNN model was performed using DenseNet-169.

Assessing the possibility of using large language models in ocular surface diseases.

Aim: To assess the possibility of using different large language models (LLMs) in ocular surface diseases by selecting five different LLMS to test their accuracy in answering specialized questions related to ocular surface diseases: ChatGPT-4, ChatGPT-3.5, Claude 2, PaLM2, and SenseNova.

Methods: A group of experienced ophthalmology professors were asked to develop a 100-question single-choice question on ocular surface diseases designed to assess the performance of LLMs and human participants in answering ophthalmology specialty exam questions.

Heavy metals impact environmental capacity of oasis soils in Qinghai-Tibet Plateau dry zone.

The Tibetan Plateau is known as the "third pole of the world," and plateau oases are a key component of plateau ecosystems. Under natural conditions, the ecosystems on the Tibetan Plateau contain relatively low levels of heavy metals. However, the overexploitation of resources by humans for production and living has affected the quality of soils in the Qinghai-Tibet region, whereby the environmental capacity is decreasing.

Control Power in Continuous Variable Controlled Quantum Teleportation.

Controlled quantum teleportation is an important extension of multipartite quantum teleportation, which plays an indispensable role in building quantum networks. Compared with discrete variable counterparts, continuous variable controlled quantum teleportation can generate entanglement deterministically and exhibit higher superiority of the supervisor's authority. Here, we define a measure to quantify the control power in continuous variable controlled quantum teleportation via Greenberger-Horne-Zeilinger-type entangled coherent state channels.

-deficient MDBK cell based on CRISPR/Cas9 technology for enhancing IBRV replication.

(IBR), characterized by acute respiratory lesions in cattle, is a major infectious disease caused by (BoAHV-1). Control of this disease is primarily depending on vaccination. Madin-Darby bovine kidney cells (MDBK) being the main host cells and the important production platform for IBR vaccines.

TRPV1 Promotes Periodontitis Tissue Inflammation and Oxidative Damage by Regulating STAT3 Signaling Pathway.

Aims: Periodontitis is a chronic disease affecting adult oral health. Transient receptor potential vanilloid 1 (TRPV1) expression is shown to upregulate in many inflammatory diseases. Nevertheless, its biological potential along with the molecular mechanism in periodontitis is unclear.