LASSO Logistic Regression was Used to Analyze the Risk Factors for Cauda Equina Injury Secondary to Lumbar Spinal Stenosis and to Build a Risk Model.

Objective: To analyze the risk factors for secondary cauda equina injury in lumbar spinal stenosis using LASSO logistic regression and to construct a risk prediction model in the form of a nomogram.

Methods: Patients with lumbar spinal stenosis were divided into a secondary injury group (90 cases) and a non-secondary injury group (110 cases). LASSO logistic regression was applied, and a risk nomogram was generated.

Clonal longevity and the enigmatic flowering of woody bamboos are associated with rates of protein evolution.

Rates of protein evolution (d/d) vary widely across the tree of life. In plants, both life-history traits and GC-biased gene conversion (gBGC) are thought to contribute to this variation, although disentangling their individual contributions remains a challenge. Using information on variation in life-history traits and molecular data in 148 species from Poaceae subfamilies Bambusoideae (mostly woody) and Pooideae (exclusively herbaceous), we investigated the relative importance of modes of reproduction and the non-selective forces of gBGC on protein evolutionary rates between the two subfamilies.

Functional Yb-doped fiber with a bat-type refractive index distribution for beyond kilowatt all-fiber single-frequency laser amplification.

High-power single-frequency fiber lasers with diffraction-limited spots are indispensable for a wide range of photonic applications and are particularly in advanced detection and sensing technologies. However, the simultaneous achievement of kilowatt-level output power and diffraction-limited beam quality has remained elusive in all reported single-frequency fiber laser systems to date, primarily due to limitations imposed by the stimulated Brillouin scattering (SBS) effect and transverse mode instability (TMI) effect. In this study, we demonstrate the design and manufacturing of an ultra-low numerical aperture (NA) functional Yb-doped fiber featuring a bat-type refractive index distribution, specifically engineered for single-frequency laser amplification.

Kilowatt-level narrow-linewidth cascaded Yb-Raman fiber amplifier at 1178 nm.

A kilowatt-level narrow-linewidth all-fiber amplifier at 1178 nm based on cascaded Yb-Raman hybrid gains is demonstrated for the first time, to the best of our knowledge. Three phase-modulated single-frequency fiber sources operating at 1071 nm, 1120 nm, and 1178 nm are applied in this amplifier. They can extract Yb ion gain and function as a temporally stable 1st-order Raman-pumped laser, a 2nd-order Raman-pumped laser, and a Raman signal laser, respectively.

1.4 kW 1030 nm all-fiber amplifier with ∼3.5 GHz linewidth assisted by confined Yb-doped active fiber and cascaded phase modulation technique.

This study presents a high power 1030 nm narrow linewidth fiber amplifier employing confined-doped fiber. Through comparative analysis of conventional fully-doped and novel confined-doped fibers (both with 30/250 µm core/cladding diameter), we demonstrate the latter's superior performance in high-power short-wavelength operation, exhibiting enhanced threshold of transverse mode instability while maintaining high laser efficiency and amplified spontaneous emission suppression. As a result, a 1430 W signal laser with 3.

Seasonal climate change characteristics of the Mu Us Sandy Land based on long time scale.

The study of seasonal-scale climate-vegetation coupling mechanisms is important for coordinating desertification control and climate adaptation. Taking the Mu Us Sandy Land (MUSL) as a case study, we gathered meteorological data from 1959 to 2019 (including maximum temperature, minimum temperature, and precipitation) for seasonal analysis. We conducted M-K significance and mutation analysis, Morlet wavelet periodicity analysis and correlation analysis and investigated the effects of various seasonal and annual climate factors on NDVI using NDVI values collected from 1999 to 2019.

Mode control in a 7.2 kW near-single-mode monolithic fiber amplifier employing the gain-tailoring effect.

In this paper, we investigate the performance of a high-power confined doped fiber amplifier to achieve high power and high beam quality. The impact of various factors, including core diameter, doping ratio, and numerical aperture, on the gain-tailoring effect is explored to establish fiber parameters for attaining near single mode beam quality at high power, taking into account variations in coiling diameters. Based on simulation results, a confined doped fiber with a low numerical aperture, featuring a core/cladding diameter of 30/250 μm and a relative doping ratio of 0.

Methyltransferase-like factor 14 pathway and its relationship with pathological stages in patients undergoing surgery for colorectal cancer.

Background: Epigenetic involvement of methyltransferase-like factor 14 (METTL14) in tumor development has not been clearly defined.

Aim: To investigate METTL14 expression and its relationship with pathological stage in patients undergoing radical surgery for colorectal cancer (CRC).

Methods: This retrospective study included 80 patients with CRC who were admitted to the Third Hospital of Hefei and the Western District of the First Affiliated Hospital of Anhui Medical University between June 2021 and June 2024.

Reassessing the phylogenetic relationships of and Saccharinae (Poaceae) using plastome and nuclear ribosomal sequences.

The sugarcane subtribe Saccharinae (Andropogoneae, Poaceae) was established in 1846, but its delimitation has long been debated. Moreover, the relationships among the genera of Saccharinae remain unclear, and there is no consensus on whether , a small genus in tropical Asia with only two species, should be included. Here, we performed phylogenomic analyses using whole plastomes (69 of them newly sequenced) from 132 individuals, representing 65 species in 19 related genera.

Generalized Valence Bond-Based Block-Correlated Coupled Cluster Theory with up to Five-Pair Correlation for Accurate Static Correlation of Strongly Correlated Systems.

Generalized valence bond-based block-correlated coupled cluster theory with up to five-pair correlation (GVB-BCCC5) has been presented for the first time to describe the electronic structures of strongly correlated systems with singlet ground states. Several efficient techniques have been employed to make GVB-BCCC5 calculations practical for strongly correlated systems. We then apply this method to investigate various systems, including potential energy surfaces of a hydrogen cuboid lattice and a phosphorus cluster (P); relative energies of two isomers for C and VH; and the bond dissociation energy in a metal-oxide compound, FeO.

Transverse mode coupling in monolithic few-mode fiber laser oscillators.

Transverse mode instability (TMI), induced by nonlinear thermal-optical coupling, poses a primary challenge for the power scaling of fiber lasers. In the fiber oscillator, a sealed resonant cavity, TMI could become particularly complex due to the mode competition during the laser oscillation. While traditional theories of TMI predominantly address two-mode coupling, this paper explores the TMI phenomena in few-mode fiber oscillators utilizing a holistic approach that includes solving steady-state thermal-optic coupling equations.

Impact of Potentially Antioxidant Probiotic Strains on Fermentation Quality and Antioxidant Status in Alfalfa Silage.

The study aimed to characterize the antioxidant properties of isolated lactic acid bacteria (LAB) and assess their impacts on fermentation quality and antioxidant status in alfalfa silage. Two LAB strains of XY15 and XY20 and a reference strain of J17 were subjected to antioxidant property evaluation. This was followed by inoculation into alfalfa silage.

An Efficient Staggered Scheme for Solving the Poromechanics Problem of Quasi-Static Cardiac Perfusion.

The ventricles can be considered a type of poroelastic material, where the mass and pressure of the interstitial fluid, along with the displacement of the skeleton, are the three primary physical quantities of interest. Based on the free energy function of the poroelastic material, we propose a simplified model that requires only two fields to be directly solved, with another quantity obtained through post-processing. To solve this model, we first discretize the equations with the backward Euler scheme and finite element method, leading to a nonlinear system of equations, which can be solved using the Newton method in a monolithic way.

Subgenome asymmetry of gibberellins-related genes plays important roles in regulating rapid growth of bamboos.

Rapid growth is an innovative trait of woody bamboos that has been widely studied. However, the genetic basis and evolution of this trait are poorly understood. Taking advantage of genomic resources of 11 representative bamboos at different ploidal levels, we integrated morphological, physiological, and transcriptomic datasets to investigate rapid growth.

TRIM22 inhibits the metastasis of colorectal cancer through facilitating β-Catenin degradation.

Tripartite motif-containing 22 (TRIM22), a member of the tripartite motif protein family, has emerged as a putative tumor suppressor in various cancers. Nevertheless, its specific role and clinical significance in colorectal cancer (CRC) remain poorly characterized. Herein, we observed that TRIM22 expression was frequently downregulated in primary CRC tissues and was significantly correlated with better prognosis.

BVOCs' role in dynamic shifts of summer ozone formation regimes across China and policy implications.

Biogenic volatile organic compounds (BVOCs) are crucial players in atmospheric chemistry, significantly impacting the formation of tropospheric ozone (O₃). While China has made substantial strides in reducing anthropogenic VOC (AVOCs) emissions, O₃ levels persist, highlighting the complex interplay between biogenic and anthropogenic sources. A critical knowledge gap exists in understanding how BVOC emissions influence ozone formation regimes (OFRs) and how this knowledge can inform effective air quality policies.

Determining the status of tertiary lymphoid structures in invasive pulmonary adenocarcinoma based on chest CT radiomic features.

Objectives: The aim of this study was to determine the status of tertiary lymphoid structures (TLSs) using radiomic features in patients with invasive pulmonary adenocarcinoma (IA).

Methods: In this retrospective study, patients with IA from November 2015 to March 2024 were recruited from two independent centers (center 1, training and internal test data set; center 2, external test data set). TLS was divided into two groups according to hematoxylin-eosin staining.

Prediction of microvascular invasion in hepatocellular carcinoma using a preoperative serum C-reactive protein-based nomogram.

Microvascular invasion (MVI) diagnosis relies on postoperative pathological examinations, underscoring the urgent need for a novel diagnostic method. C-Reactive Protein (CRP), has shown significant relevance to hepatocellular carcinoma (HCC) prognosis. This study aims to explore the relationship between preoperative serum CRP levels and microvascular invasion in hepatocellular carcinoma and develop a nomogram model for predicting MVI.

Development of a dual-mode lateral flow assay based on structure-guided aptamers for the detection of capsaicin in gutter oils.

The construction of structure-guided aptamers and the ultra-sensitive aptamer-based lateral flow assays (Apt-LFA) integrated detection method hold significant potential for food analysis. Using an engineered modified sequence strategy, we successfully developed the aptamer Cap-1-2M4, significantly enhancing its affinity for capsaicin (CAP) to 0.6197 ± 0.

Glycosylation-Targeting Aptamer for the Feasible Construction of a Dual Aptamer-Based Plasmonic Immunosandwich Assay in Cancer Diagnostics.

Fibroblast activation protein (FAP) is an important antigen in the tumor microenvironment, which plays a crucial role in promoting extracellular matrix remodeling and tumor cell metastasis. A circulating form of soluble FAP has also been identified in the serum, becoming a biomarker for pan-cancer diagnosis and prognosis. However, the current peptide substrate-based enzymatic activity detection or antibody-dependent detection methods have been hindered by insufficient selectivity and complex operations, so it is valuable to develop effective nucleic acid aptamers as FAP affinity ligands.

Haplotype-resolved nonaploid genome provides insights into flowering in bamboos.

Woody bamboos (Bambusoideae) are renowned for its polyploidy and rare flowering. is one of the bamboo species with the highest chromosome count (104) in the subfamily and has the highest heterozygosity of all sequenced bamboo genomes so far. Compared with other bamboo species, it can efficiently utilize exogenous hormones to regulate flowering, providing valuable insights into the hormonal regulation of bamboo flowering.

Enhancement of microalgae co-cultivation self-settling performance and water purificationcapacity of microalgae biofilm.

Cultivating microalgae for the remediation of aquaculture wastewater provides a promising solution for pollution control. However, the economic viability of this approach faces challenges due to the high costs associated with microalgal biomass harvesting. This study aims to address this issue by immobilizing microalgae onto coral velvet carriers, enhancing the efficiency of biomass recovery.