Articular Cartilage Inspired Ultra-Strong and Tough Bio-Based Polyurethane Nanofiber Membranes.

Bio-based polyurethanes are promising sustainable elastomers whose polymeric network structure has a decisive impact on their properties. However, existing bio-based polyurethanes face challenges in simultaneously enhancing mechanical strength and toughness. Inspired by the multilevel heterogeneous structure of articular cartilage, we propose a bionic design strategy of rigid-flexible coupled supramolecular cross-linking networks to prepare bio-based polyurethane elastomers with enhanced strength and toughness.

Highly Permeable and Liquid-Repellent Textiles with Micro-Nano-Networks for Medical and Health Protection.

Current protective clothing often lacks sufficient comfort to ensure efficient performance of healthcare workers. Developing protective textiles with high air and moisture permeability is a potential and effective solution to discomfort of medical protective clothing. However, realizing the facile production of a protective textile that combines safety and comfort remains a challenge.

Optimization of Bio-Based Polyurethane Elastic Nanofibrous Membrane via Electrospinning for Waterproof and Breathable Applications.

Bio-based polyurethane (BPU) offers excellent biocompatibility and outstanding elasticity, providing vast potential for the development of next-generation waterproof and breathable materials. However, achieving stable and uniform electrospinning of BPU remains a significant challenge. Herein, BPU with superior electrospinning performance was synthesized using poly(butylene sebacate), poly(trimethylene ether glycol), ethylene glycol, and methylene diphenyl diisocyanate (MDI) as raw materials.

Incidence, mortality, and predictive factors associated with acute respiratory distress syndrome in multiple trauma patients living in high-altitude areas: a retrospective study in Shigatse.

Background: Acute respiratory distress syndrome (ARDS) is a severe complication that can lead to fatalities in multiple trauma patients. Nevertheless, the incidence rate and early prediction of ARDS among multiple trauma patients residing in high-altitude areas remain unknown.

Methods: This study included a total of 168 multiple trauma patients who received treatment at Shigatse People's Hospital Intensive Care Unit (ICU) between January 1, 2019 and December 31, 2021.

Breathable Dual-Mode Leather-Like Nanotextile for Efficient Daytime Radiative Cooling and Heating.

Incorporating passive radiative cooling and heating into personal thermal management has attracted tremendous attention. However, most current thermal management materials are usually monofunctional with a narrow temperature regulation range, and lack breathability, softness, and stretchability, resulting in a poor wearer experience and limited application scenarios. Herein, a breathable dual-mode leather-like nanotextile (LNT) with asymmetrical wrinkle photonic microstructures and Janus wettability for highly efficient personal thermal management is developed via a one-step electrospinning technique.

A Trilayered Composite Fabric with Directional Water Transport and Resistance to Blood Penetration for Medical Protective Clothing.

Functional textiles with enhanced moisture management can facilitate sweat transport away from the skin to improve personal comfort. However, porous materials exhibit low capability of preventing the intrusion of external liquids, becoming a bottleneck in the design of medical protective clothing. Herein, a trilayered composite fabric based on a gradient wettability structure is demonstrated for directional water transport and resistance to blood penetration.

Integration of Janus Wettability and Heat Conduction in Hierarchically Designed Textiles for All-Day Personal Radiative Cooling.

Personal cooling textiles are a promising energy-free pathway for confronting serious heat-related public health threats and improving industrial worker productivity. Current cooling strategies mainly focus on passive daytime radiation, and there is a lack of research on all-day cooling methods which utilize synergistic radiative, conductive, and evaporative heat dissipation. Herein, we demonstrate a hierarchical polyurethane/silicon nitride fibrous membrane with Janus wettability fabricated via a scalable electrospinning method followed by single-side hydrophilic plasma treatment.

Anti-inflammatory labdane diterpenoids from Leonurus japonicus Houtt.

Seven undescribed labdane diterpenoids, japonicones A-G, were isolated from the aerial parts of Leonurus japonicus Houtt. Japonicones C-G contained two keto carbonyl groups in their structures attached to C-3 and C-7, which are rare for labdane diterpenoids. The structures and absolute configurations of japonicones A-G were established by means of spectroscopic analyses (HRESIMS, 1D and 2D NMR, and ECD).

[A new aurone with anti-inflammatory activity from Cleistocalyx operculatus flower buds].

A new compound(Z)-6-hydroxy-4-methoxy-5,7-dimethylaurone was isolated from Cleistocalyx operculatus flower buds. Its structure was identified by spectroscopic data including MS, ¹H-NMR, ¹³C-NMR HSQC and HMBC. A known compound, 2',4'-dihydroxy-6'-methoxy-3'5'-dimethylchalcone (DMC), was also isolated and identified,and used as material to synthesize (Z)-6-hydroxy-4-methoxy-5,7-dimethylaurone.

Two new labdane diterpenoids from aerial parts of and their anti-inflammatory activity.

Two new labdane diterpenoids, Leojaponin E () and F (), together with three known compounds were isolated from the dried herb of Houtt., Lamiaceae. Their structures were determined based on extensive spectroscopic analyses.

Relationship between molecular weight, monosaccharide composition and immunobiologic activity of Astragalus polysaccharides.

Four Astragalus polysaccharides (APS1-APS4) were isolated from the water extract of Radix Astragali and purified through ethanol precipitation with 20 %, 40 %, 60 % and 80 % ethanol, respectively. The total sugar content was measured by sulfuric acid-phenol method. Their molecular weight was determined using high performance gel permeation chromatography (HPGPC) and their monosaccharide composition was analyzed by reversed-phase high performance liquid chromatography (HPLC) after pre-column derivatization.

[Research on Chinese medicine pairs effects of Panax notoginseng and Bletilla striata before and after compatibility on contents of notoginsenosides].

To discuss the synergistic mechanism of compatible use of two medicinal herbs,Panax notoginseng and Bletilla striata, an HPLC was established to determine two ginseng saponins (20S)-ginseng saponin Rg₃ and ginseng saponin Rh₄ contained in single decoction of Panax notoginseng as well as in compound decoction of Panax notoginseng and Bletillastriata in different compatibility ratio (1∶0.5, 1∶1, 1∶2), followed by analyzing the impact of amount of notoginsenosides after compatibility. As a result, compared with the single decoction of Panax notoginseng, the contents of ginseng saponin Rg₃ and ginseng saponin Rh₄ in the compound decoction of Panax notoginseng and Bletillastriata were on the rise as the increasement of the amount of Bletillastriata.