Background: Hypertension (HTN) and obesity are leading, interrelated risk factors for cardiovascular disease, stroke, and kidney disease in the United States. Despite advances in medical therapies and public health interventions, the joint mortality burden associated with these conditions remains substantial. We sought to characterize national trends and demographic disparities in obesity- and hypertension-related mortality from 2000 to 2019 using the CDC WONDER database.
View Article and Find Full Text PDFObjective: Childhood stroke is a significant contributor to neurological morbidity often leading to debilitating outcomes. This study aimed to assess the clinical and radiological outcomes of angiographically proven central nervous system (CNS) arteriopathy in children.
Material And Methods: This prospective cohort study was conducted from June 2023 to May 2024 at The Children's Hospital, Lahore, Pakistan.
The advent of antibiotic resistance in microorganisms requires the discovery and synthesis of novel antibiotics. At the same time, human pathogens are contributing to chronic and persistent inflammation. Motivated by these two concerning issues, new antibiotic drug candidates are synthesized by incorporation of benzothiazine, pyrazole, and amide moieties in a new scaffold to create multifunctional derivatives of pyrazolo-1,2-benzothiazine.
View Article and Find Full Text PDFEcotoxicol Environ Saf
October 2024
The bioavailability of heavy metals in soil is a crucial factor in determining their potential uptake by plants and their subsequent entry into the food chain. Various methods, including traditional chemical extractants and the diffusive gradients in thin films (DGT) technique, are employed to assess this bioavailability. The bioavailability of heavy metals, particularly cadmium (Cd) and lead (Pb), is also influenced by soil texture and their concentrations in the soil solution.
View Article and Find Full Text PDFOrganophosphate esters (OPEs) are widely used as substitutes for brominated flame retardants and characterized as emerging contaminants. Due to their toxicity and persistent nature, OPEs are becoming a matter of greater concern worldwide. However, information about the pollution profile of OPEs and associated ecological risks is still scarce in environmental matrices of the South Asian region, particularly Pakistan.
View Article and Find Full Text PDFAn important component of the pathogenicity of potentially pathogenic bacteria in humans is the urease enzyme. In order to avoid the detrimental impact of ureolytic bacterial infections, the inhibition of urease enzyme appears to be an appealing approach. Therefore, in the current study, morpholine-thiophene hybrid thiosemicarbazone derivatives () were designed, synthesized and characterized through FTIR, H NMR, C NMR spectroscopy and mass spectrometry.
View Article and Find Full Text PDFPesticides are becoming more prevalent in agriculture to protect crops and increase crop yields. However, nearly all pesticides used for this purpose reach non-target crops and remain as residues for extended periods. Contamination of soil by widespread pesticide use, as well as its toxicity to humans and other living organisms, is a global concern.
View Article and Find Full Text PDFDespite the widespread usage to safeguard crops and manage pests, pesticides have detrimental effects on the environment and human health. The necessity to find sustainable agricultural techniques and meet the growing demand for food production has spurred the quest for pesticide substitutes other than traditional ones. The unique qualities of nanotechnology, including its high surface area-to-volume ratio, controlled release, and better stability, have made it a promising choice for pest management.
View Article and Find Full Text PDFSoil salinization and sodication harm soil fertility and crop production, especially in dry regions. To combat this, using biochar combined with gypsum, lime, and farm manure is a promising solution for improving salt-affected soils. In a pot experiment, cotton stick biochar (BC) was applied at a rate of 20 t/ha in combination with gypsum (G), lime (L), and farm manure (F) at rates of 5 and 10 t/ha.
View Article and Find Full Text PDFExogenous application of iron (Fe) may alleviate salinity stress in plants growing in saline soils. This comparative study evaluated the comparative residual effects of iron nanoparticles (FNp) with two other Fe sources including iron-sulphate (FS) and iron-chelate (FC) on maize ( L.) crop grown under salt stress.
View Article and Find Full Text PDFAdvances in financial inclusions have contributed to economic growth and poverty alleviation, addressing environmental implications and implementing measures to mitigate climate change. Financial inclusions force advanced countries to progress their policies in a manner that does not hinder developing countries' current and future development. Consequently, this research examined the asymmetric effects of information and communication technology (ICT), financial inclusion, consumption of primary energy, employment to population ratio, and human development index on CO2 emissions in oil-producing countries (UAE, Nigeria, Russia, Saudi Arabia, Norway, Kazakhstan, Kuwait, Iraq, USA, and Canada).
View Article and Find Full Text PDFThe contamination of farm soils with heavy metals (HMs) has raised significant concerns due to the increased bioavailability and accumulation of HMs in agricultural food crops. To address this issue, a survey experiment was conducted in the suburbs of Multan and Faisalabad to investigate the spatial distribution, bioaccumulation, translocation, and health risks of cadmium (Cd) and lead (Pb) in agricultural crops. The results show a considerable concentration of Cd and Pb in soils irrigated with wastewater, even though these levels were below the permissible limits in water and soil matrices.
View Article and Find Full Text PDFCadmium (Cd) accumulates in the vegetative tissues of rice and wheat crops, posing a serious threat in the food chain. A long-term field experiment was conducted to investigate the effects of rice husk biochar (RHB), farm manure (FM), press mud (PrM), and poultry manure (PM) on the growth, yield, and economics of wheat and rice crops grown with sewage water. The results showed that RHB increased wheat plant height (27%, 66%, 70%), spike-length (33%, 99%, 56%), straw yield (21%, 51%, 49%), and grain yield (42%, 63%, 65%) in year-1, year-2, and year-3, than respective controls.
View Article and Find Full Text PDFExogenous application of phytohormones is getting promising results in alleviating abiotic stresses, particularly heavy metal (HMs). Jasmonate (JA) and brassinosteroid (BR) have crosstalk in bamboo plants, reflecting a burgeoning area of investigation. Lead (Pb) is the most common pollutant in the environment, adversely affecting plants and human health.
View Article and Find Full Text PDFBiochar (BC) has shown great potential in remediating heavy metal(loid)s (HMs) contamination in paddy fields. Variation in feedstock sources, pyrolysis temperatures, modification methods, and application rates of BC can result in great changes in its effects on HM bioavailability and bioaccumulation in soil-rice systems and remediation mechanisms. Meanwhile, there is a lack of application guidelines for BC with specific properties and application rates when targeting rice fields contaminated with certain HMs.
View Article and Find Full Text PDFPlants (Basel)
October 2023
Salinity adversely affects the plant's morphological characteristics, but the utilization of aqueous algal extracts (AE) ameliorates this negative impact. In this study, the application of AE derived from and strains effectively reversed the decline in biomass allocation and water relations, both in normal and salt-stressed conditions. The simultaneous application of both extracts in salt-affected soil notably enhanced key parameters, such as chlorophyll content (15%), carotene content (1%), photosynthesis (25%), stomatal conductance (7%), and transpiration rate (23%), surpassing those observed in the application of both AE in salt-affected as compared to salinity stress control.
View Article and Find Full Text PDFChemosphere
January 2024
Chemosphere
November 2023
Salinity has emerged as a major threat to food security and safety around the globe. The crop production on agricultural lands is squeezing due to aridity, climate change and low quality of irrigation water. The present study investigated the effect of biogenic silicon (Si) sources including wheat straw biochar (BC-ws), cotton stick biochar (BC-cs), rice husk feedstock (RH-fs), and sugarcane bagasse (SB), on the growth of two consecutive maize (Zea mays L.
View Article and Find Full Text PDFClimate change has become the global concern due to its drastic effects on the environment. Agriculture sector is the backbone of food security which remains at the disposal of climate change. Heat stress is the is the most concerning effect of climate change which negatively affect the plant growth and potential yields.
View Article and Find Full Text PDFThe cadmium contamination of soil is an alarming issue worldwide and among various mitigation strategies, nanotechnology mediated management of Cd contamination has become a well-accepted approach. The Cerium Oxide Nanoparticles (CeO-NPs) are widely being explored for their novel works in Agro-Industry and Environment, including stress mitigation in crops. Very little work is reported regarding role of CeO-NPs in management of Cd contamination in cereal crops like wheat.
View Article and Find Full Text PDFSci Total Environ
November 2023
Cadmium (Cd) contamination in rice fields has been recognized as a severe global agro-environmental issue. To reach the goal of controlling Cd risk, we must pay more attention and obtain an in-depth understanding of the environmental behavior, uptake and translocation of Cd in soil-rice systems. However, to date, these aspects still lack sufficient exploration and summary.
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