Non-alcoholic steatohepatitis incidence in patients with psoriasis vulgaris.

Background And Aims: Non-alcoholic steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease (NAFLD), characterized by hepatic inflammation and damage due to fat accumulation. Psoriasis patients show higher NASH incidence due to overlapping risk factors like obesity and insulin resistance. The study aimed to determine the incidence of non-alcoholic steatohepatitis in patients with psoriasis vulgaris.

Nitrogen-doped bismuth molybdenum carbide: A superior heterojunction catalyst for electrochemical nitrite sensing in food.

In this work, we developed a high-performance electrochemical sensor for sensitive and selective detection of nitrite in environmental and food samples, utilizing bismuth-modified nitrogen-doped molybdenum carbide nanocomposites (Bi@N-Mo₂C) as the active material The nanocomposite was synthesized through a two-step process involving the formation of Bi@PD-Mo hollow spheres via self-assembly polymerization, followed by thermal carbonization to yield Bi@N-Mo₂C. The resulting material was immobilized on a glassy carbon electrode, enhancing electrochemical activity, as confirmed by Cyclic voltammetry and differential pulse voltammetry through its excellent sensitivity, reproducibility, and long-term stability. Sensor exhibited a broad linear detection range (14.

Effects on Jump Shooting Accuracy when Using Unstable Surfaces for Functional Balance Training of Youth Basketball Players.

This study examined the effects of a 10-week functional balance training program using unstable surfaces on dynamic postural control, lower-limb power, and technical shooting performance in adolescent male basketball players. Twenty-one participants were assigned to an experimental group (n = 11; age 16.14 ± 1.

Engineering graphyne-supported single-atom catalysts for efficient nitrogen reduction to ammonia: First-principles investigation.

The electrochemical nitrogen reduction reaction (NRR) offers a sustainable route to ammonia production under ambient conditions but remains limited by inert N ≡ N bond activation and competitive hydrogen evolution reaction (HER). Herein, we employ first-principles density functional theory (DFT) to systematically investigate the NRR activity of graphyne (GY) doped with single-atom transition metals (Fe, Mo, Ru, W). Structural analysis reveals strong binding and minimal distortion of the TM dopants on the porous, π-conjugated GY scaffold, with Fe-GY and W-GY exhibiting the highest stability.

Effective deep learning aided vehicle classification approach using Seismic Data.

Intelligent transportation systems (ITSs) significantly enhance traffic safety and management globally. A critical component of these systems is vehicle classification (VC), which supports vital applications such as congestion control, traffic monitoring, accident avoidance, etc. Traditional classification algorithms rely heavily on visual or sensor-based data (e.

Seasonal variations in acute kidney injury incidence and outcomes: a multicenter prospective observational study highlighting socioeconomic disparities.

Background: Kuwait experiences cool winters and hot summers. We evaluated the impact of ambient temperature in these two seasons on acute kidney injury (AKI) incidence and outcomes, and assessed difference between Kuwaitis and non-Kuwaitis.

Method: Clinical and 30-day outcome data from AKI patients who were admitted to seven public hospitals during winter and summer of 2021 were prospectively collected.

Eco-Friendly Removal and IoT-Based Monitoring of CO Emissions Released from Gasoline Engines Using a Novel Compact Nomex/Activated Carbon Sandwich Filter.

A novel cost-effective, rapid, and eco-friendly method was described for the removal of carbon dioxide (CO) from the gaseous emissions of gasoline engines. This involved the use of a sandwich filter (~10 cm diameter) made of a nonwoven poly (-phenylene isophthalamide) (Nomex) fabric loaded with a thin layer of activated carbon. The optimized filter, with an activated carbon mass of 2.

Drug prescribing pattern in upper respiratory tract infections among the pediatric population attending outpatient clinics in pediatric hospitals.

Background: Upper respiratory tract infections (URTIs) are one of the most frequent causes of childhood school leave and morbidity.

Aim: To study the present trend of medications' prescribing pattern utilized in URTIs among the pediatric population attending outpatient clinics in pediatric hospitals.

Methods: This analytical observational cross-sectional research was conducted in 200 children aged 1-10 years with URTIs attending the pediatric outpatient clinics in pediatric hospitals, one of which is an educational hospital, from July 2018 to August 2020.

Preparation and Evaluation of Tadalafil-Loaded Nanoemulgel for Transdermal Delivery in Cold-Induced Vasoconstriction: A Potential Therapy for Raynaud's Phenomenon.

Raynaud's phenomenon (RP) is characterized by an exaggerated vasoconstrictive response of small blood vessels in the fingers and toes to cold or stress. Oral therapy with tadalafil (TDL), a phosphodiesterase-5 inhibitor, is limited by systemic side effects and reduced patient compliance. This study aimed to develop and evaluate a TDL-loaded nanoemulgel for transdermal delivery as a non-invasive treatment alternative for cold-induced vasoconstriction.

Enoxaparin dosing for venous thromboembolism prophylaxis in hospitalized underweight adult patients: a retrospective cohort study.

Background: Enoxaparin is commonly used for venous thromboembolism (VTE) prophylaxis in adult hospitalized patients. Although anti-Xa levels are inversely related to body weight, limited studies evaluated clinical outcomes of dose reduction in the underweight population.

Objective: To compare the incidence of bleeding and VTE in underweight patients receiving reduced doses of enoxaparin (< 40 mg daily) versus the standard dose (40 mg daily) for VTE prophylaxis.

Retraction notice to "Examinations of mechanical, and shielding properties of CeO reinforced BO-ZnF-ErO-ZnO glasses for gamma-ray shield and neutron applications" [Heliyon 9 (2023) e14435].

[This retracts the article DOI: 10.1016/j.heliyon.

Medial Tibial Stress Syndrome: A Scoping Review of Epidemiology, Biomechanics, and Risk Factors.

Regular physical activity confers numerous health and social benefits; however, activity-related lower-limb overuse injuries are prevalent. Medial tibial stress syndrome (MTSS) is a common overuse injury of the lower extremity. It is frequently observed in athletes and in military personnel.

A Systematic Approach for Incorporating Structural Flexibility in High-Throughput Computational Screening of Metal-Organic Frameworks for Xylene Separation.

Separation of xylene isomers poses a significant challenge due to their similar physicochemical properties. Currently, zeolites are utilized as adsorbents for this purpose in the chemical industry despite suboptimal separation performance. With tunable pore size and chemical functionality, metal-organic frameworks (MOFs) are promising adsorbents for separation.

Stock and vertical distribution of microplastics and tire and road wear particles into the soils of a high-traffic roadside biofiltration swale.

Urban highways are a central infrastructure in megacities and represent diverse sources of microplastic pollution. Understanding the relative contribution of these microplastic sources, including the abrasion of macrolitter and the generation of tire and road wear particles (TRWP) is necessary to better assess the sources and fate of microplastics in terrestrial environments. This study focuses on microplastic (MP) and TRWP infiltration in the soil of a biofiltration swale alongside a high-traffic highway in the north of Paris, France.

Hydrostable Fluorinated Metal-Organic Frameworks for CO Capture from a Wet Flue Gas: Multiscale Computational Screening.

Metal-organic frameworks (MOFs) are promising adsorbents for CO capture due to readily tunable porosity and diverse functionality; however, their performance is deteriorated by the presence of HO in a flue gas. Fluorinated MOFs (FMOFs) may impede HO interaction with frameworks and enhance CO adsorption under humid conditions. In this study, a multiscale computational screening study is reported to identify the top FMOFs for CO capture from a wet flue gas.

Safety of Different Weight-Based Dosing Strategies of Intravenous Acyclovir in Obese Patients: A Retrospective Cohort Study.

Background: In obese patients receiving intravenous (IV) acyclovir, conflicting data exist regarding the risk of acute kidney injury (AKI) with different weight-based dosing strategies: total body weight (TBW), adjusted body weight (AdjBW), and ideal body weight (IBW).

Objective: We aimed to compare the safety of the 3 dosing strategies in obese patients.

Methods: A retrospective cohort study including obese patients who received IV acyclovir during their inpatient admissions.

Iron improves the antiviral activity of NK cells.

Natural killer (NK) cells are innate immune cells that play a crucial role as a first line of defense against viral infections and tumor development. Iron is an essential nutrient for immune cells, but it can also pose biochemical risks such as the production of reactive oxygen species. The importance of iron for the NK cell function has gained increasing recognition.

Toward a Generalizable Machine-Learned Potential for Metal-Organic Frameworks.

Machine-learned potentials (MLPs) have transformed the field of molecular simulations by scaling "quantum-accurate" potentials to linear time complexity. While they provide more accurate reproduction of physical properties as compared to empirical force fields, it is still computationally costly to generate their training data sets from ab initio calculations. Despite the emergence of foundational or general MLPs for organic molecules and dense materials, it is unexplored if one general MLP can be effectively developed for a wide variety of nanoporous metal-organic frameworks (MOFs) with different chemical moieties and geometric properties.

Disparities in patterns and outcomes of dyslipidemic patients with acute coronary syndrome: A tertiary cardiac center registry.

Graphical Abstract: Dyslipidemia Patterns in Patients with Acute Coronary Syndrome.Image 1.

Exploring the drug delivery capabilities of NbC MXene functionalized with oxygen and fluorine: A DFT study.

MXenes quantum dots (QDs), including NbC, NbCO, and NbCF, are emerging materials with exceptional structural, electronic, and optical properties, making them highly suitable for biomedical applications. This study investigates the structural optimization, stability, electronic properties, and drug-loading potential of these QDs using fluorouracil (Flu) as a model drug. Structural analyses show that the functionalization of NbC with O and F atoms enhances stability, with binding energies (BEs) of 7.

The feasibility of utilizing the open dynamic interaction network (ODIN) app to assess rEMA data across 30 days among those recovering from alcohol use disorders.

Preliminary data from a prospective micro-longitudinal study (30 days) that examined the co-evolution of return to use risk among people diagnosed with an alcohol use disorder (AUD) in residential substance treatment is presented. Data assessed the feasibility of using the open dynamic interaction network (ODIN) responsive ecological momentary assessment (rEMA). rEMA collected daily estimates on affect, urges, sober-support engagement, and use.

Correction: A survey on the knowledge and attitudes of pharmacists towards the application of antimicrobial therapeutic drug monitoring and its challenges in Qatar.

[This corrects the article DOI: 10.1371/journal.pone.

Accelerating Discovery of Mechanically Stable Metal-Organic Frameworks for Vinylidene Fluoride Storage by Active Learning.

Metal-organic frameworks (MOFs) are versatile nanoporous materials for a wide variety of important applications. Recently, a handful of MOFs have been explored for the storage of toxic fluorinated gases (Keasler et al. 1455), yet the potential of a great number of MOFs for such an environmentally sustainable application has not been thoroughly investigated.

Nanoscopic Insights into the Collapse of Metal-Organic Frameworks during Solvent Evacuation: Molecular Simulation Investigation.

Many metal-organic frameworks (MOFs) undergo structural collapse upon solvent evacuation during activation, which is attributed to the capillary force generated by the solvent. However, little effort has been devoted to unveiling the nature of such a force. Herein, we employ molecular dynamics (MD) simulations to investigate the evacuation of different solvents in two MOFs (MOF-5 and UMCM-9).