Phage-coated vinorelbine-loaded hexagonal boron nitride for targeted lung cancer therapy via chemo-photothermal treatment.

Lung cancer remains one of the most widespread and difficult-to-treat malignancies, with current treatments approaches often lacking specificity and resulting in significant off-target toxicity. Nanoparticle-based drug delivery systems (DDS) have emerged as a promising strategy to overcome these limitations. Hexagonal boron nitrides (h-BN) nanoparticles (NPs) have gained attention due to their high photothermal (PT) conversion efficiency and versatile surface functionalization capabilities, making them attractive candidates for targeted cancer therapy.

Engineering graphyne-supported single-atom catalysts for efficient nitrogen reduction to ammonia: First-principles investigation.

The electrochemical nitrogen reduction reaction (NRR) offers a sustainable route to ammonia production under ambient conditions but remains limited by inert N ≡ N bond activation and competitive hydrogen evolution reaction (HER). Herein, we employ first-principles density functional theory (DFT) to systematically investigate the NRR activity of graphyne (GY) doped with single-atom transition metals (Fe, Mo, Ru, W). Structural analysis reveals strong binding and minimal distortion of the TM dopants on the porous, π-conjugated GY scaffold, with Fe-GY and W-GY exhibiting the highest stability.

Chitosan-metalloporphyrin as a green catalyst for methylene blue degradation: Performance insights.

5, 10, 15, 20-tetrakis(4-methoxyphenyl)porphyrin (TMPP) was synthesized and subsequently metallized with cobalt(II) to form Co(II)TMPP. This complex was then immobilized onto a chitosan (CTS) support, resulting in the composite Co(II)TMPP@CTS, which was utilized for the degradation of methylene blue (MB) in aqueous solutions. Fourier-transform infrared spectroscopy (FT-IR) confirmed strong coordination between cobalt metal and nitrogen atoms within the chitosan matrix.

A novel isatin Schiff based cerium complex: synthesis, characterization, antimicrobial activity and molecular docking studies.

In this work, a novel isatin-Schiff base L2 had been synthesized through a simple reaction between isatin and 2-amino-5-methylthio-1,3,4-thiadiazole. The produced Schiff base L2 was then subjected to a hydrothermal reaction with cerium chloride to produce the cerium (III)-Schiff base complex C2. Several spectroscopic methods, including mass spectra, FT-IR, elemental analysis, UV-vis, C-NMR, H-NMR, Thermogravimetric Analysis, HR-TEM, and FE-SEM/EDX, were used to completely characterize the produced L2 and C2.

Ionophore-modified polyaniline-based optode for the determination of hydrogen sulfite levels in beverages, wastewater, and soil.

Sulfite is a very important species, affecting human health, plant and animal life, and environmental sustainability. In this study, for the first time, an ionophore-based ion-selective optode was constructed for hydrogen sulfite determination in beverages, such as Birell® and Sprite®, water, and soil samples; instead of normal pH-chromoionophores, polyaniline film was precipitated on a glass slide and used for the transduction of the sensation mechanism. The ionophore-modified polyaniline-based optode incorporated thiourea derivative as an ionophore and tridodecyl methyl ammonium chloride as an ion-exchanger.

Relation between blood levels of heavy metals and some markers of oxidative stress among boys with neuropathic bladder and posterior urethral valve.

Background: The status of heavy metals in children with lower urinary tract pathology that may harm the upper tract, e.g., neuropathic bladder and posterior urethral valve and its relationship with oxidative stress has not been adequately investigated.

Chemically modified rice husk as an effective adsorbent for removal of palladium ions.

Bio-matrix of rice husk and Mobil Composition of Matter No. 41 (MCM-41) was modified with alizarin red S for preconcentration of Pd prior flame atomic absorption spectrometric determination. The prepared bio-matrix (RH@MCM-41@ARS) was characterized by Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscope (TEM), scanning electron microscope, energy dispersive X-ray spectrometer (SEM/EDX) and surface area studies.