Phage-coated vinorelbine-loaded hexagonal boron nitride for targeted lung cancer therapy via chemo-photothermal treatment.

Lung cancer remains one of the most widespread and difficult-to-treat malignancies, with current treatments approaches often lacking specificity and resulting in significant off-target toxicity. Nanoparticle-based drug delivery systems (DDS) have emerged as a promising strategy to overcome these limitations. Hexagonal boron nitrides (h-BN) nanoparticles (NPs) have gained attention due to their high photothermal (PT) conversion efficiency and versatile surface functionalization capabilities, making them attractive candidates for targeted cancer therapy.

Preparation and characterization of a novel magnetic nano adsorbent for removal of metal ions.

As a result of global urbanization and industrialization, heavy metals are one of the hazardous contaminants facing the world. The adsorption process using agricultural wastes can achieve one of the sustainable development goals for wastewater treatment and resource recovery. Moringa and tea extracts were utilized to synthesize iron nanoparticles for the treatment of aqueous solutions containing heavy metal ions (Cu2+, Pb2+, Se2+, Zn2+, and Cr6+).

Synthesis, characterization, biological potency, and molecular docking of Co, Ni and Cu complexes of a benzoyl isothiocyanate based ligand.

The primary objective of the present study was to produce metal complexes of HDAP ligand (N,N'-((pyridine-2,6-diylbis(azanediyl))bis(carbonothioyl))dibenzamide) derived from 2,6-diaminopyridine and benzoyl isothiocyanate with either ML or ML stoichiometry. There are three distinct coordination complexes obtained with the formulas [Co(HDAP)]·HO, [Ni(HDAP)Cl(HO)]·HO, and [Cu(HDAP)Cl]·3HO. The confirmation of the structures of all derivatives was achieved through the utilization of several analytical techniques, including FT-IR, UV-Vis, NMR, GC-MS, PXRD, SEM, TEM analysis, and QM calculations.

Efficient Photocatalytic Degradation of Congo Red Dye Using Facilely Synthesized and Characterized MgAlO Nanoparticles.

The discharge of congo red dye into water sources by factories has been associated with a range of health concerns, such as cancer, redness, skin irritation, and allergic reactions. As a result, this research focused on the cost-effective and straightforward production of MgAlO nanoparticles by using the Pechini sol-gel process. Subsequently, these nanoparticles were employed for the successful photocatalytic decomposition of congo red dye.

Facile synthesis and characterization of FeO/analcime nanocomposite for the efficient removal of Cu(II) and Cd(II) ions from aqueous media.

In the water purification field, heavy metal pollution is a problem that causes severe risk aversion. This study aimed to examine the disposal of cadmium and copper ions from aqueous solutions by a novel FeO/analcime nanocomposite. A field emission scanning electron microscope (FE-SEM), Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction were used to characterize the synthesized products.

An quantitative investigation on the synergistic effect of capsaicin and 5-fluorouracil encapsulated into lipid nanocapsules to treat breast cancer.

Background: Breast cancer conventional therapeutics are effective; however, they encounter some limitations including multidrug resistance, the presence of pharmacological barriers, and non-selectivity which hinder their optimal therapeutic efficacy.

Aim: Overcoming such drawbacks necessitates the development of efficient drug vehicles including lipid-based nanoparticles. This study aimed to quantitatively investigate the synergistic therapeutic effect of the novel combination of capsaicin and 5-fluorouracil (5-FU) encapsulated in lipid nanocapsules (LNCs).

Development of Ion Character Property Relationship (IC-PR) for Removal of 13-Metal Ions by Employing a Novel Green Adsorbent .

The novel absorbent was applied for the removal of thirteen selected metal ions from a distilled water solution of each metal by the batch adsorption method. The optimization remediation parameters of the metal ions for the batch adsorption approach were developed, which were the initial concentrations (60 ppm), contact time (60 min) and pH (7). The basic properties of metal ion affected the adsorption results; therefore, 21 properties of metal ions were selected, which are called "descriptors".

Facile Synthesis and Characterizations of Mixed Metal Oxide Nanoparticles for the Efficient Photocatalytic Degradation of Rhodamine B and Congo Red Dyes.

Photocatalytic degradation has been suggested to be a cheap and efficient way to dispose of organic pollutants, such as dyes. Therefore, our research team strives to produce nanophotocatalysts in a simple and inexpensive way. In this work, the Pechini sol-gel technique was employed for the facile synthesis of MnZnFeO/FeO and FeMnCoO/FeO as mixed metal oxide nanoparticles for the efficient photocatalytic degradation of Rhodamine B and Congo Red dyes.

Layer-by-layer development of chitosan/alginate-based platelet-mimicking nanocapsules for augmenting doxorubicin cytotoxicity against breast cancer.

Breast carcinoma is considered one of the most invasive and life-threatening malignancies in females. Mastectomy, radiation therapy, hormone therapy and chemotherapy are the most common treatment choices for breast cancer. Doxorubicin (DOX) is one of the most regularly utilized medications in breast cancer protocols.

Defatted Seed Residue of as a Novel, Renewable and Green Biosorbent for Removal of Selected Heavy Metals from Wastewater: Kinetic and Isothermal Study.

The present work was aimed at studying the biosorption of two important heavy metals, viz. Pb and Cr, using defatted seed residue of as biosorbent. As this study for the biosorption of the selected biosorbent is being carried out for the first time, optimization of the% sorption was carried out with the help of Taguchi method.

Functionalized MOF as a Sensitive Spectroscopic Probe for Hg, Co, and Al Ions Detection in Aqueous Media.

A modified metal-organic framework (MOF) named Al-MIL-53-N=SA-Br was synthesized via a Schiff-base reaction between the MOFs (Al-MIL-53-NH) and 5-bromo salicylaldehyde. The robust functionalized Al-MIL-53-N=SA-Br was used as a novel spectrophotometric sensor for detecting Hg, Co, and Al ions. In a wide range of concentrations, the absorption spectral intensity of Al-MIL-53-N=SA-Br increased linearly upon increasing the concentration of Hg, Co, and Al ions.

Fabrication of hybrid nanocomposite derived from chitosan as efficient electrode materials for supercapacitor.

A novel high-performance supercapacitor was fabricated using spinal (nickel ferrite) nanoparticles uniformly implanted into nitrogen-doped carbon matrix. The nanocomposite was fabricated with bimetallic polymer complexes for the first time. The fabricated nanocomposite was characterized using FTIR, TGA, Raman, XRD, BET, XPS, SEM and TEM technique.