Primary aldosteronism diagnosis in the intensive care unit: resistant alkalosis and hypokalemia during severe sepsis with hyperlactatemia: a case report.

Background: Primary aldosteronism screening indications include hypertension (resistant, severe, early onset, with stroke/other comorbidities/sleep apnea), hypokalemia, adrenal incidentaloma, and primary aldosteronism first-degree relatives. We report rare diagnosis of primary aldosteronism in intensive care unit setting, characterized by resistant alkalosis and hypokalemia during severe sepsis with hyperlactatemia.

Case Presentation: A 50-year-old Asian-Indian male patient with 18-year history of hypertension (blood pressure 166/104 mmHg) presented with acute septicemia and septic shock following an outpatient urethral dilatation.

Parathyroid Carcinoma Complicated by Parathyromatosis and Refractory Hypercalcemia.

Parathyroid carcinoma (PC) is a rare malignancy. In January 2022, a 41-year-old woman presented with weight loss, proximal muscle weakness, and bone pain. She was diagnosed with severe hypercalcemia with serum calcium of 15.

Primary and "Pre-Primary" Aldosteronism in Resistant Hypertension: A Practical, Pragmatic, and Prudent Approach in Resource-Limited Milieu.

Introduction Primary aldosteronism (PA), once considered rare, is now recognized as the most common cause of secondary hypertension, accounting for almost a quarter of resistant hypertension (RH) cases. Despite this, PA remains underdiagnosed, with an extremely low percentage of RH patients undergoing screening. Methods In a specialty diabetes-endocrinology clinic, the aldosterone:renin ratio (ARR) was assessed in 115 consecutive RH patients (ages 21-93 years; 47% male; 87% with type 2 diabetes).