Gastrosplenic fistula is a rare complication, most often secondary to gastric or splenic lymphoma. Severe gastrosplenic fistula can cause life-threatening upper gastrointestinal bleeding, making early diagnosis and intervention critical for a favorable prognosis. Currently, surgical intervention remains the primary treatment; however, outcomes are often suboptimal.
View Article and Find Full Text PDFAdditively Manufactured metallic implants face a critical challenge in simultaneously promoting osteogenesis and preventing infection, two competing requirements in complex orthopedic applications such as implant-associated infections. This study presents a novel strategy combining Cu alloying and heat treatment for biodegradable zinc-based implants fabricated by laser powder bed fusion (L-PBF), in order to address infected bone repair. After alloying, the as-built Zn-2Cu implants showed limited enhancement compared to pure Zn due to the microstructure dominated by solid solution.
View Article and Find Full Text PDFAdditively manufactured biodegradable metals demonstrate great potential in orthopedic implants, enabling patient-specific designs and eliminating the need for secondary surgeries through degradation. Zinc (Zn)-magnesium (Mg) alloys reconcile the dilemma between Zn's low biological activity and Mg's rapid degradation, and become promising bone-repair materials. However, Zn-Mg alloys currently fabricated via additive manufacturing exhibit high strength but low ductility, and the effects and mechanisms by which Mg influences their degradation and bone regeneration remain unclear.
View Article and Find Full Text PDFNat Mater
July 2025
High-temperature capacitive energy storage demands that dielectric materials maintain low electrical conduction loss and high discharged energy density under thermal extremes. The temperature capability of dielectric polymers is limited to below 200 °C, lagging behind requirements for high-power and harsh-condition electronics. Here we report a molecular topology design for dielectric polymers with mechanical bonds that overcomes this obstacle, where cyclic polyethers are threaded onto the axles of various polyimides.
View Article and Find Full Text PDFBioact Mater
February 2025
Zn-based biodegradable metals (BMs) are regarded as revolutionary biomaterials for bone implants. However, their clinical application is limited by insufficient mechanical properties, delayed degradation, and overdose-induced Zn toxicity. Herein, innovative multi-material additive manufacturing (MMAM) is deployed to construct a Zn/titanium (Ti) hetero-structured composite.
View Article and Find Full Text PDFFront Oncol
September 2023
Testicular mucinous cystadenoma is a rare benign testicular tumor with the characteristics of being potentially malignant and showing atypical clinical symptoms; this article reports a case of a primary testicular mucinous cystadenoma misdiagnosed as testicular teratoma by ultrasound. A 69-year-old man was admitted to the hospital because of a 1-year history of left-sided testicular enlargement with scrotal swelling and no obvious abnormalities on laboratory tests. Ultrasound examination revealed solid-mass lesions in the left testicle, suggesting a high probability of teratoma, and contrast-enhanced magnetic resonance imaging (MRI) examination suggested an increased possibility of epidermoid cysts.
View Article and Find Full Text PDFThe growing need for high-power and compact-size energy storage in modern electronic and electrical systems demands polymer film capacitors with excellent temperature capability. However, conventional polymer dielectrics feature dramatic deterioration in capacitive performance under concurrent high temperature and electric field because the high thermal stability traditionally relies on the conjugated, planar molecular segments in the polymer chains. Herein, inspired by the stable double helix structures of deoxyribonucleic acid, spiral-structured dielectric polymers that exhibit simultaneous high thermal stability and great capacitive performance are demonstrated.
View Article and Find Full Text PDFAttaining compact energy storage under extreme temperature conditions is of paramount importance in the development of advanced dielectric materials. The polymer composite approach has proved effective towards this goal, and addressing the correlation between filler distribution and electrical properties is foremost in designing composite dielectrics, especially in multifiller systems. Here, the design of a bi-gradient polymer composite dielectric using an integrated framework based on the phase field model is reported.
View Article and Find Full Text PDFMany mainstream dielectric energy storage technologies in the emergent applications, such as renewable energy, electrified transportations and advanced propulsion systems, are usually required to operate under harsh-temperature conditions. However, excellent capacitive performance and thermal stability tend to be mutually exclusive in the current polymer dielectric materials and applications. Here, we report a strategy to tailor structural units for the design of high-temperature polymer dielectrics.
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