Genome-Wide Identification of ATP-Binding Cassette (ABC) Transporter Gene Family and Their Expression Analysis in Response to Anthocyanin Transportation in the Fruit Peel of Eggplant ( L.).

The ATP-binding cassette (ABC) gene family represents one of the most extensive and evolutionarily conserved groups of proteins, characterized by ATP-dependent transporters that mediate the movement of substrates across cellular membranes. Despite their well-documented functions in various biological processes, the specific contributions of ABC transporters in eggplant ( L.) remain unexplored.

Triazine amine compounds synergistically enhance the efficacy against fluconazole-resistant Candida albicans with fluconazole by inhibiting cell wall synthesis.

Invasive fungal infections caused by Candida albicans are associated with high morbidity and mortality, highlighting the urgent need for novel antifungal agents. Compound 2 m in combination with fluconazole exhibited a significant synergistic effect (fractional inhibitory concentration index range: 0.15-0.

Impact of white goosefoot, sunflower, wheat, and soybean on the developmental and fecundity performance of the beet webworm, Loxostege sticticalis (Lepidoptera: Pyralidae).

The beet webworm Loxostege sticticalis (Lepidoptera: Pyralidae), is an invasive and polyphagous pest, posing a severe threat to food security, agriculture, and animal production. In this study, we examined the biological parameters of L. sticticalis on four host plants: white goosefoot, Chenopodium album (Caryophyllales: Amaranthaceae), sunflower, Helianthus annuus L (Asterales: Compositae), wheat, Triticum aestivum L (Poales: Poaceae), and soybean, Glycine max (L.

A novel nomogram for predicting osteoporosis with low back pain among the patients in Wenshan Zhuang and Miao Autonomous Prefecture of China.

Background: Low back pain (LBP) is one of the most common symptoms of osteoporosis (OP), but LBP caused by osteoporosis can easily be masked by other causes, leading to misdiagnosis. However, there are currently no convenient tools available to identify patients with low back pain caused by osteoporosis.

Methods: We consecutively enrolled 769 patients diagnosed with low back pain in our hospital from January 2019 to March 2024.

Effects of electroacupuncture on neural function and the expression of inflammation-related proteins NLRP3/caspase-1 in rats with ischemic stroke.

This study aimed to investigate the neuroprotective effects of electroacupuncture (EA) at the Baihui and Dazhui acupoints in a rat model of ischemia-reperfusion injury. Ninety-six male Sprague-Dawley rats were randomly assigned to four groups ( n  = 24 per group): Sham, middle cerebral artery occlusion (MCAO), MCAO+EA, and MCAO+MCC950. The MCAO model was induced using filament embolization.

Relationship of immune response with intestinal flora and metabolic reprogramming in patients with non-small cell lung cancer.

Numerous research conducted in recent years has revealed that gut microbial dysbiosis, such as modifications in composition and activity, might influence lung tissue homeostasis through specific pathways, thereby promoting susceptibility to lung diseases. The development and progression of lung cancer, as well as the effectiveness of immunotherapy are closely associated with gut flora and metabolites, which influence immunological and inflammatory responses. During abnormal proliferation, non-small cell lung cancer cells acquire more substances and energy by altering their own metabolic pathways.

Umbelliferone Enhances Immune Function in Cyclophosphamide-Induced Immunosuppressed Mice Histidine and Purine Metabolism Regulation.

Background: Chemotherapy-induced immunosuppression significantly impacts patient's quality of life. Umbelliferone (UMB) is known for its anti-inflammatory, antioxidant, and anti-apoptotic properties, but its effects on cyclophosphamide (CTX)-induced immunosuppression need further study.

Methods: We established a CTX-induced immunosuppressed mouse model and administered varying doses of UMB.

Polycystic Ovary Syndrome and the Potential for Nanomaterial-Based Drug Delivery in Therapy of This Disease.

Polycystic ovary syndrome (PCOS) is the predominant endocrine disorder among women of reproductive age and represents the leading cause of anovulatory infertility, which imposes a considerable health and economic burden. Currently, medications used to treat PCOS can lead to certain adverse reactions, such as affecting fertility and increasing the risk of venous thrombosis. Drug delivery systems utilizing nanomaterials, characterized by prolonged half-life, precision-targeted delivery, enhanced bioavailability, and reduced toxicity, are currently being employed in the management of PCOS.

Overexpression of a Grape WRKY Transcription Factor Improves the Resistance to Cold and Salt of .

Plants are often exposed to biotic or abiotic stress, which can seriously impede their growth and development. In recent years, researchers have focused especially on the study of plant responses to biotic and abiotic stress. As one of the most widely planted grapevine rootstocks, 'Beta' has been extensively proven to be highly resistant to stress.

Cuproptosis in stroke: focusing on pathogenesis and treatment.

Annually, more than 15 million people worldwide suffer from stroke, a condition linked to high mortality and disability rates. This disease significantly affects daily life, impairing everyday functioning, executive function, and cognition. Moreover, stroke severely restricts patients' ability to perform daily activities, diminishing their overall quality of life.

Investigating the role of mitochondrial DNA D-loop variants, haplotypes, and copy number in polycystic ovary syndrome: implications for clinical phenotypes in the Chinese population.

Background: The presence of genetic variations in mitochondrial DNA (mtDNA) has been associated with a diverse array of diseases. The objective of this study was to examine the correlations between mtDNA D-loop, its haplotypes, and polycystic ovary syndrome (PCOS) in the Chinese population, and the associations between mtDNA D-loop and symptoms of PCOS. The study also sought to determine whether the mtDNA copy number in Chinese patients with PCOS differed from that of individuals in the control group.

Decomposing the decoupling relationship between energy consumption and economic growth in China's agricultural sector.

Sustainable food supply is affected by high energy consumption and negative environmental effects. Regarding the national strategy of "carbon peaking and carbon neutrality targets", the decoupling between energy consumption and economic growth in China's agriculture has received significant attention. Therefore, this study first presents a descriptive analysis of the energy consumption in China's agricultural sector from 2000 to 2019, before analyzing the decoupling state between energy consumption and agricultural economic growth at the national and provincial levels using the Tapio decoupling index.

Research progress in the risk factors and screening assessment of dysphagia in the elderly.

With the aging of the population, the incidence of dysphagia has gradually increased and become a major clinical and public health issue. Early screening of dysphagia in high-risk populations is crucial to identify the risk factors of dysphagia and carry out effective interventions and health management in advance. In this study, the current epidemiology, hazards, risk factors, preventive, and therapeutic measures of dysphagia were comprehensively reviewed, and a literature review of screening instruments commonly used globally was conducted, focusing on their intended populations, main indicators, descriptions, and characteristics.

Spatiotemporal Dynamics of Wetland in Dongting Lake Based on Multi-Source Satellite Observation Data during Last Two Decades.

Monitoring the dynamics of wetland resources has practical value for wetland protection, restoration and sustainable utilization. Dongting Lake wetland reserves are well known for both their intra-annual and inter-annual dynamic changes due to the effects of natural or human factors. However, most wetland monitoring research has failed to consider the seasonal wetlands, which is the most fragile wetland type, requiring more attention.

Depression in polycystic ovary syndrome: Focusing on pathogenesis and treatment.

Polycystic ovary syndrome (PCOS) is one of the most prevalent gynecological endocrine conditions affecting reproductive women. It can feature a variety of symptoms, such as obesity, insulin resistance, skin conditions, and infertility. Women with PCOS are susceptible to illnesses including mood disorders, diabetes, hypertension, and dyslipidemia.

Preventive Electroacupuncture Alleviates Oxidative Stress and Inflammation via Keap1/Nrf2/HO-1 Pathway in Rats with Cyclophosphamide-Induced Premature Ovarian Insufficiency.

Electroacupuncture (EA) is a popular therapeutic therapy for premature ovarian insufficiency (POI). However, little has been known about the underlying processes of EA therapy. To investigate the benefit of EA and reveal the mechanism, thirty SD female rats were allocated into the control, model, sham, EA, and GnRHa groups at random.

Effect of Acupoint Embedding on Serum Leptin and Hypothalamus Leptin Receptor Expression in Rats with Simple Obesity.

Background: Acupoint embedding treatment on obesity has been applied in clinical practice for many years and has achieved obvious efficacy. However, animal experimental studies on acupoint embedding are relatively few, and its mechanism remains unclear.

Methods: We established a simple obese rat model using a high-fat diet for 8 weeks.

Acupuncture treatment on attention deficit hyperactivity disorder: A protocol for systematic review and meta-analysis.

Background: Attention Deficit Hyperactivity Disorder (ADHD) is the most common behavioral disorder in childhood. Acupuncture treatment of ADHD has formed a relatively systematic theoretical and clinical treatment system which achieved satisfactory results. However, there has been no systematic evaluation of its effectiveness and safety.