Molecular Evolution and Zoonotic Potential of Muju Virus (Orthohantavirus puumalaense) in Craseomys regulus, Republic of Korea.

Orthohantavirus puumalaense causes hemorrhagic fever with renal syndrome in Europe, with Puumala virus (PUUV) as its primary representative. Muju virus (MUJV), harbored by Craseomys regulus, an Arvicolinae rodent species endemic to the Republic of Korea (ROK), is also a genotype of O. puumalaense.

Longitudinal study of Orthohantavirus hantanense in Apodemus agrarius and disease risk assessment in the Republic of Korea during 2000-2019.

Orthohantavirus hantanense (HTNV) is a zoonotic pathogen transmitted by rodents and the causative agent of hemorrhagic fever with renal syndrome (HFRS) in East Asia. Long-term reservoir population ecology studies have enhanced our understanding of hantavirus infection patterns and support disease risk assessments critical for military and civilian populations in HTNV high-risk areas. Here, we evaluated fluctuations in the population dynamics of Apodemus agrarius, the primary reservoir of HTNV, assessed hantavirus seroprevalence, and conducted a descriptive analysis of HFRS disease risks in the Republic of Korea (ROK).

Phylogenetic diversity and molecular evolution of Hantaan virus harbored by Apodemus chejuensis on Jeju Island, Republic of Korea, 2022-2023.

Background: Hantaan virus (HTNV), hosted by Apodemus spp., is a well-recognized causative agent of hemorrhagic fever with renal syndrome (HFRS) and poses a crucial global public health concern. Based on the current evidence, HTNV carried by A.

Comparison of Artificial Intelligence-Derived Heart Age with Chronological Age Using Normal Sinus Electrocardiograms in Patients with No Evidence of Cardiac Disease.

: Chronological age (CA) is commonly used in clinical decision-making, yet it may not accurately reflect biological aging. Recent advances in artificial intelligence (AI) allow estimation of electrocardiogram (ECG)-derived heart age, which may serve as a non-invasive biomarker for physiological aging. This study aimed to develop and validate a deep learning model to predict ECG-heart age in individuals with no structural heart disease.

Spectrally sharp magnetic excitations above the critical temperature in a frustrated Weyl semimetal.

The rare-earth α-pyrochlore iridates are a prospective class of conducting frustrated magnets where electronic correlations, large spin-orbit coupling, and geometrical frustration interplay, leading to a rich set of magnetic and electronic phases. Despite their intriguing properties, the magnetic order and excitations in this fundamental class of topological quantum materials remain poorly understood due to challenges in growing large single crystals and insufficient microscopic information on their temperature-dependent phases. Here, by combining state-of-the-art thin-film synthesis, resonant elastic and inelastic X-ray scattering, spin wave analysis, and dynamical spin susceptibility calculations, we unequivocally reveal the presence of spectrally sharp, gapped magnetic excitations in YIrO that surprisingly persist well above the Néel transition temperature, signaling the presence of a quasi-universal regime connected to fluctuations on frustrated lattices.

Molecular evolution and reassortment dynamics of Orthohantavirus hantanense revealed through longitudinal genomic surveillance in the Republic of Korea.

Orthohantavirus hantanense (HTNV), a major cause of hemorrhagic fever with renal syndrome (HFRS), remains a public health concern in East Asia. We investigated its evolutionary history, reassortment, and genetic diversity by analyzing 123 complete genomes from the Republic of Korea (1976-2023), comprising the most comprehensive dataset to date from this endemic region. Bayesian coalescent analyses estimated evolutionary rates ranging from 1.

Discovery and genomic characterization of Ulleung virus harbored by Crocidura utsuryoensis on Ulleung Island in Republic of Korea.

Hantaviruses are zoonotic RNA viruses that cause hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome, posing significant public health risks. This study reports the identification and genomic characterization of Ulleung virus (ULLEV), a newly discovered genetic lineage of Orthohantavirus jejuense harbored by Crocidura utsuryoensis, a shrew species endemic to Ulleung Island, Republic of Korea. In 2009, a surveillance effort involving 62 shrews revealed a molecular prevalence of 64.

Understanding cross-talk-induced anode slippage in high-voltage mid-Ni NCM/graphite full cells.

While high-voltage operation of mid-Ni layered oxide cathodes in full-cell Li-ion batteries is essential for achieving high energy density, it inevitably accelerates electrode degradation, ultimately resulting in capacity loss. However, the underlying degradation mechanisms under high-voltage conditions remain poorly understood. In this study, we reveal that anode slippage - induced by cross-talk-driven surface degradation - is the dominant factor in capacity fade during high-voltage (4.

Lactiplantibacillus plantarum WB4201, WB4202, and WB4203 Modulated Adipogenesis, Lipogenesis, and Fatty Acid β-oxidation in 3T3-L1 Cells.

Obesity is a growing public health concern characterized by excessive lipid accumulation and metabolic dysfunction. In this study, Lactiplantibacillus plantarum WB4201, WB4202, and WB4203 were isolated from kimchi and evaluated for their probiotic properties and anti-obesity effects. These strains exhibited strong probiotic potential, demonstrating high gastric tolerance, intestinal adhesion, and safety profiles.

Atomic force microscope-guided nanoscale 3D patterning for carbon nanofibers with Raman spectroscopy.

Carbon nanotubes (CNTs) have attracted significant attention across various fields due to their exceptional electrical, thermal, and mechanical properties. Integrating CNTs with 3D patterning technology, particularly in the manufacturing of vertically stacked CNT fibers, is becoming increasingly important. The objective of this study is to utilize 3D patterning techniques to fabricate CNT nanofibers and to conduct Raman spectroscopy analysis.

The classical-to-quantum crossover in the strain-induced ferroelectric transition in SrTiO membranes.

Mechanical strain presents an effective control over symmetry-breaking phase transitions. In quantum paraelectric SrTiO, strain can induce ferroelectric order via modification of the local Ti potential energy landscape. However, brittle bulk materials can only withstand limited strain range (~0.

Tunable magnons of an antiferromagnetic Mott insulator via interfacial metal-insulator transitions.

Antiferromagnetic insulators present a promising alternative to ferromagnets due to their ultrafast spin dynamics essential for low-energy terahertz spintronic device applications. Magnons, i.e.

Detection and characterization of Langya virus in (the Ussuri white-toothed shrew), Republic of Korea.

Langya virus (LayV) is the only documented zoonotic agent within the shrew borne genus. Other species, including Gamak virus and Daeryeong virus, have been discovered in the Republic of Korea, highlighting the prevalence of this genus in the region. We retrospectively analyzed metagenomic next-generation sequencing of two (the Ussuri white-toothed shrew) kidney samples from 2017, followed by paramyxovirus screening of 24 kidney samples from the same species collected in 2023.

Clinical Utilization and Infrastructure of Radiation Therapy in Korea in 2020 and 2021.

Background/aim: This study aimed to evaluate the clinical status of radiation therapy (RT), including the RT utilization (RTU) rate and infrastructure of RT in Korea in 2020 and 2021.

Patients And Methods: Patient data for individuals undergoing RT in 2020 and 2021 were sourced from the Health Insurance Review and Assessment Service. Through these data, we assessed the following aspects: total number of patients who received RT in 2020 and 2021, RTU rate for patients with cancer, RTU rate by cancer diagnosis, number of patients treated with RT by age, RT rate by region, rate of hypofractionated RT for breast cancer, and RT by specific modality.

Large asymmetric anomalous Nernst effect in the antiferromagnet SrIrSnO.

A large anomalous Nernst effect is essential for thermoelectric energy-harvesting in the transverse geometry without external magnetic field. It's often connected with anomalous Hall effect, especially when electronic Berry curvature is believed to be the driving force. This approach implicitly assumes the same symmetry for the Nernst and Hall coefficients, which is however not necessarily true.

Novel human coronavirus in an infant patient with pneumonia, Republic of Korea.

Coronaviruses (CoVs) pose a significant threat to public health, causing a wide spectrum of clinical manifestations and outcomes. Beyond precipitating global outbreaks, Human CoVs (HCoVs) are frequently found among patients with respiratory infections. To date, limited attention has been directed towards alphacoronaviruses due to their low prevalence and fatality rates.

Epidemiological surveillance and phylogenetic diversity of Orthohantavirus hantanense using high-fidelity nanopore sequencing, Republic of Korea.

Background: Orthohantavirus hantanense (HTNV) poses a substantial global public health threat due to its role in causing hemorrhagic fever with renal syndrome (HFRS). HTNV outbreaks are particularly prevalent in the Gyeonggi and Gangwon Provinces of the Republic of Korea (ROK). This study aimed to evaluate the application of advanced nanopore sequencing and bioinformatics to generate complete genome sequences of HTNV, with the objective of accurately identifying infection sources and analyzing their genetic diversity.

Web Visualization for Spatiotemporal Genomic Epidemiology, Annotation, and Mutation Dynamics of Orthohantavirus hantanense Using Nextstrain.

The phylogeographic inference approach aims to connect genomic data with epidemiology to understand the spread and evolution of pathogens using visualization of spatiotemporal reconstructions. Orthohantavirus hantanense (HTNV), the causative agent of hemorrhagic fever with renal syndrome (HFRS), represents a significant global public health concern. Here, we introduce a localized Nextstrain platform for HTNV, offering a comprehensive resource for facilitating spatiotemporal genomic surveillance and the study of evolutionary dynamics of viral genomes.

Assessing Hwa-byung Vulnerability Using the Hwa-byung Personality Scale: a comparative study of machine learning approaches.

Objectives: To develop and compare machine learning models to classify individuals vulnerable to Hwa-byung (HB) using an existing HB personality scale and to evaluate the efficacy of these models in predicting HB vulnerability.

Methods: We analyzed data from 500 Korean adults (aged 19-44) using HB personality and symptom scales. We used various machine learning techniques, including the random forest classifier (RFC), XGBoost classifier, logistic regression, and their ensemble method (RFC-XGC-LR).

Detection and characterization of Langya virus in , Republic of Korea.

This study reports the identification of Langya virus Korea (LayV KOR) during the surveillance of shrews in the Republic of Korea. LayV KOR represents the first identification of LayV outside of China, exhibiting approximately 80% and 95.5% homologies at nucleotide and amino acid levels.

Development of a Short-Form Hwa-Byung Symptom Scale Using Machine Learning Approaches.

: Hwa-byung (HB), also known as "anger syndrome" or "fire illness", is a culture-bound syndrome primarily observed among Koreans. This study aims to develop a short-form version of the HB symptom scale using machine learning approaches. Methods: Utilizing exploratory factor analysis (EFA) and various machine learning techniques (i.

Molecular detection and genomic characterization of Samak Micromys paramyxovirus-1 and -2 in Micromys minutus, Republic of Korea.

Background: The discovery of viruses in small mammalian populations, particularly rodents, has expanded the family Paramyxoviridae. The overlap in habitats between rodents and humans increases the risk of zoonotic events, underscoring the importance of active surveillance. Rodent species, such as Apodemus agrarius, are natural hosts for Paramyxoviridae in the Republic of Korea (ROK).