Capturing Community Living Experiences and Health of Korean Community Spinal Cord Injury Population: A Cross-Sectional Survey.

(1) Background: People living with spinal cord injury (SCI) face numerous challenges in their lives in terms of health conditions, everyday activity, and participation in society, which are not fully recognized. To address such issues, a community survey with 125 questions for people living with SCI was conducted and the response rates, population characteristics, health and functioning problems are reported. (2) Methods: The survey questionnaire comprised 125 questions on SCI characteristics, health conditions, activities, participation, and environmental and personal factors.

Current status and future perspectives of minimally invasive liver surgery for hepatocellular carcinoma.

The use of laparoscopic liver resection has rapidly increased. According to two international consensus meetings, certain resection methods are already considered standard procedures for liver resection, especially for small malignant tumors located on the liver surface or in the anterolateral segments of the liver. However, further studies and international consensus meetings are required for laparoscopic procedures to be accepted as standard procedures for highly complex hepatectomies, major hepatectomies, anatomical resections, and laparoscopic donor hepatectomies.

Effects of acupuncture on musculoskeletal pain: an evidence map.

Background: Musculoskeletal pain is a leading cause of disability and reduced quality of life worldwide. Given the growing interest in complementary and alternative therapies, acupuncture has been widely explored as a potential treatment for alleviating musculoskeletal pain. This evidence map aimed to identify, describe, and summarize the current available evidence about acupuncture interventions on musculoskeletal pain.

Impact of work and environmental factors on quality of life in community-dwelling spinal cord injury individuals in South Korea using latent profile analysis.

Objective: To classify Koreans with spinal cord injury into groups with similar levels of life satisfaction and analyse the differences in life satisfaction between the groups, and identify the factors influencing their quality of life.

Design: A cross-sectional study was conducted.

Subjects: The International Spinal Cord Injury Survey of 711 persons with traumatic or non-traumatic spinal cord injury was used.

Surgical feasibility for the single-incision laparoscopic left-sided anatomical liver resection: A cohort comparative study.

Background: Single-incision laparoscopic liver resection represents an evolution in minimally invasive liver surgery. However, its safety, feasibility, and advantages over conventional multiport laparoscopic liver resection remain incompletely defined. This study aimed to evaluate perioperative and oncologic outcomes of single-incision laparoscopic liver resection in left-sided anatomical liver resections.

Comprehensive state smoke-free policies as a predictor of cognitive impairment among older Americans: the Health and Retirement Study.

Introduction: Exposure to secondhand smoke is an important risk factor for cognitive impairment. This study aimed to investigate the associations between statewide comprehensive smoke-free policies and cognitive impairment among older Americans.

Methods: Using a difference-in-differences approach, we analysed data in a US nationally representative sample of adults aged 51 and older collected between 1998 and 2020 from the Health and Retirement Study.

State E-Cigarette Flavor Restrictions and Tobacco Product Use in Youths and Adults.

Importance: Seven states have policies restricting the sale of flavored e-cigarettes. Limited evidence exists regarding these policies' association with the use of tobacco products across age groups.

Objective: To evaluate associations of e-cigarette flavor restriction policies with e-cigarette and cigarette use by age group over multiple years.

Korean medicine registry for allergic rhinitis in real-world settings (KOREA-R): a multicenter registry protocol.

Background: Allergic rhinitis is a prevalent immune disorder with a significant impact on quality of life and socioeconomic burden. Korean Medicine treatments such as herbal medicine and acupuncture are widely utilized for allergic rhinitis due to clinical effectiveness and patient preferences. In particular, herbal decoctions, a key component of Korean Medicine treatment for allergic rhinitis, offer personalized treatment but pose challenges for randomized controlled trials due to the difficulty of placebo development.

Signaling by intracellular β-adrenergic receptors regulates AMPA receptor trafficking and synaptic plasticity.

Signaling by norepinephrine (NE) via adrenergic receptors (ARs) mediates attention, yet the underlying molecular mechanisms are largely unknown. AMPA receptors (AMPARs) form a complex with βARs, G, adenylyl cyclase, and protein kinase A (PKA) to augment AMPAR phosphorylation and, thereby, surface expression. We show that signaling by intracellular βARs is required for these effects and two different forms of long-term potentiation (LTP) that depend on βAR signaling and phosphorylation of the AMPAR GluA1 subunit on S845.

Acupuncture for insomnia.

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of acupuncture in the treatment of insomnia.

US state implementation of policies restricting sales of flavoured E-cigarettes: a qualitative analysis.

Background: E-cigarettes are the most popular nicotine product among youth in the USA and the majority of young people use products with flavours such as mint, menthol, fruit and candy. Between December 2019 and December 2022, seven US states and the District of Columbia put in place restrictions on the sale of flavoured e-cigarettes. Studies of e-cigarette flavour restrictions have found varied policy effects across different populations.

Mitochondrial proteome landscape unveils key insights into melanoma severity and treatment strategies.

Background: Melanoma, the deadliest form of skin cancer, exhibits resistance to conventional therapies, particularly in advanced and metastatic stages. Mitochondrial pathways, including oxidative phosphorylation and mitochondrial translation, have emerged as critical drivers of melanoma progression and therapy resistance. This study investigates the mitochondrial proteome in melanoma to uncover novel therapeutic vulnerabilities.

Large Language Model-Assisted Surgical Consent Forms in Non-English Language: Content Analysis and Readability Evaluation.

Background: Surgical consent forms convey critical information; yet, their complex language can limit patient comprehension. Large language models (LLMs) can simplify complex information and improve readability, but evidence of the impact of LLM-generated modifications on content preservation in non-English consent forms is lacking.

Objective: This study evaluates the impact of LLM-assisted editing on the readability and content quality of surgical consent forms in Korean-particularly consent documents for standardized liver resection-across multiple institutions.

Effect of herbal medicine on gut microbiome and symptoms in anorexic patients with atopic dermatitis: a randomized controlled trial.

Introduction: Atopic dermatitis (AD) is often associated with gastrointestinal symptoms, including anorexia and alterations in the gut microbiome. A traditional East Asian herbal medicine (BJT; in Chinese, in Japanese) has been commonly used to manage AD and anorexia. This study aimed to evaluate the effects and safety of BJT in anorexic patients with AD and to investigate its therapeutic mechanism through gut microbiome analysis.

Comparison of Reduced-Port Totally Robotic Pancreaticoduodenectomy with Conventional Totally Robotic and Laparoscopic Pancreaticoduodenectomy.

Reduced-port totally robotic pancreaticoduodenectomy (rpRPD) has been introduced to address limitations of conventional robotic pancreaticoduodenectomy (cRPD), particularly regarding assistant mobility and visualization. This study aimed to evaluate the clinical feasibility and procedural consistency of rpRPD in comparison with cRPD and laparoscopic pancreaticoduodenectomy (LPD). : We conducted a retrospective cohort study of patients who underwent pancreaticoduodenectomy between January 2015 and December 2024.

Novel Benchmark for Robotic Liver Resection - Bridging Tradition with Innovation.

Objective: To establish benchmark cutoffs for robotic liver resection (R-LR), encompassing both major and minor resections, and to determine the impact of patient selection on outcomes.

Background: R-LR is a key advancement in minimally invasive liver surgery but lacks standardized benchmarks, especially for minor resections. While guidelines endorse R-LR, its role in optimizing outcomes remains unclear.

Development of an Immunodeficient Pig Model for Pancreatic Cancer Xenotransplantation Using Splenectomy, Thymectomy, and Oral Immunosuppression.

: Animal models are widely used in medical research, but most are limited to small or medium-sized species due to logistical constraints. However, pancreatic cancer research and surgical xenograft models require large animals with anatomical similarities to humans and minimal immune rejection. This study evaluates the feasibility of an operative immunodeficient pig model for patient-derived xenografts.

Effects of Low and High Doses of Deoxynivalenol on Growth Performance, Blood Biochemistry, Histology, Metabolites, and Microbial Community in Adult Rats.

Deoxynivalenol (DON) is a widespread mycotoxin which contaminates several crops, including maize, wheat, and barley. In this study, we investigated the effects of orally administered DON on growth performance, blood biochemistry, histology, the gut microbiome, and metabolism in rats. Six-week-old rats, acclimatized for one week, were subjected to different dietary treatments for 42 days, as follows: CON (control): 0.

Effects of Deoxynivalenol Contamination on Growth Performance, Blood Biochemistry, Histology, Metabolomics, and the Microbiota: A Subacute Dose Oral Toxicity Study in Rats.

Deoxynivalenol (DON), one of the most common mycotoxins, is frequently found in foods. This study investigated the effects of orally administered DON on the blood biochemical parameters, growth performance, histology, microbial composition, and metabolism of rats. After a 1-week adaptation period, 4-week-old rats were administered 0.

"Obesity Paradox" as a new insight from long-term survivors in pancreatic cancer patients.

Background: Obesity is traditionally associated with poor outcomes. However, the recently emerging concept of the "obesity paradox" suggests that obese cancer patients have better survival rates than non-obese patients. While this phenomenon has been confirmed in several cancers, its relevance to pancreatic cancer remains unclear.

Case Report: Long-term complications of subcutaneous ureteral bypass migration in an adult female Papillon.

A 6-year-old spayed female 4.4-kg Papillon with only the left kidney presented with vomiting. Imaging unveiled ureterolithiasis and hydronephrosis, while serum chemistry displayed elevated creatinine, blood urea nitrogen, and C-reactive protein.

A Prospective, Multicenter, Randomized, Noninferiority Trial of Stopad Versus Tachosil for Hemostasis After Liver Resection.

Background: Hemostatic products are widely used to control bleeding in hepatic resections. Stopad is a pad-type hemostatic agent containing carboxymethyl chitosan and recombinant thrombin-like hemocoagulase.

Methods: We conducted a prospective, multicenter, randomized, noninferiority study of Stopad vs.

Hybrid Approach to Classifying Histological Subtypes of Non-small Cell Lung Cancer (NSCLC): Combining Radiomics and Deep Learning Features from CT Images.

This study aimed to develop a hybrid model combining radiomics and deep learning features derived from computed tomography (CT) images to classify histological subtypes of non-small cell lung cancer (NSCLC). We analyzed CT images and radiomics features from 235 patients with NSCLC, including 110 with adenocarcinoma (ADC) and 112 with squamous cell carcinoma (SCC). The dataset was split into a training set (75%) and a test set (25%).