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Objectives: To develop and compare machine learning models to classify individuals vulnerable to Hwa-byung (HB) using an existing HB personality scale and to evaluate the efficacy of these models in predicting HB vulnerability.
Methods: We analyzed data from 500 Korean adults (aged 19-44) using HB personality and symptom scales. We used various machine learning techniques, including the random forest classifier (RFC), XGBoost classifier, logistic regression, and their ensemble method (RFC-XGC-LR). The models were developed using recursive feature elimination with cross-validation for feature selection and evaluated using multiple performance metrics, including accuracy, precision, recall, specificity, and area under the receiver operating characteristic curve (AUROC).
Results: The 16 items on the HB personality scale were identified as optimal features to predict high HB symptom scores requiring further clinical evaluation. The ensemble model slightly outperformed the other models, with an accuracy of 0.80 and an AUROC of 0.86, in the test set. Notably, item 16 ("") of the HB personality scale showed the greatest importance in predicting HB vulnerability across all models. Although all models showed consistent performance across training, validation, and test sets, the RFC model exhibited signs of slight overfitting, with a higher AUROC of 0.97 in the training dataset compared to 0.85 in the validation and 0.86 in the test datasets.
Conclusion: Machine learning models, particularly the ensemble method, show capabilities promising for screening individuals with high HB symptom scores based on personality traits, potentially facilitating early referral for clinical evaluation. These models can improve the efficiency and accuracy of the HB risk assessment in clinical settings, potentially aiding early intervention and prevention strategies.
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http://dx.doi.org/10.3831/KPI.2024.27.4.358 | DOI Listing |
JMIR Res Protoc
September 2025
Department of Health Services Research & Administration, College of Public Health, University of Nebraska Medical Center, Omaha, NE, United States.
Background: With the availability of more advanced and effective treatments, life expectancy has improved among patients with metastatic breast cancer (MBC), but this makes communication with their medical oncologist more complex. Some patients struggle to learn about their therapeutic options and to understand and articulate their preferences. Mobile health (mHealth) apps can enhance patient-provider communication, playing a crucial role in the diagnosis, treatment, quality of life, and outcomes for patients living with MBC.
View Article and Find Full Text PDFJMIR Res Protoc
September 2025
Institute of Higher Education and Research in Healthcare, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Background: In pediatric intensive care units, pain, sedation, delirium, and iatrogenic withdrawal syndrome (IWS) must be managed as interrelated conditions. Although clinical practice guidelines (CPGs) exist, new evidence needs to be incorporated, gaps in recommendations addressed, and recommendations adapted to the European context.
Objective: This protocol describes the development of the first patient- and family-informed European guideline for managing pain, sedation, delirium, and IWS by the European Society of Paediatric and Neonatal Intensive Care.
JAMA Netw Open
September 2025
Department of Social Epidemiology, Graduate School of Medicine and School of Public Health, Kyoto University, Kyoto, Japan.
Importance: Previous studies have suggested that social participation helps prevent depression among older adults. However, evidence is lacking about whether the preventive benefits vary among individuals and who would benefit most.
Objective: To examine the sociodemographic, behavioral, and health-related heterogeneity in the association between social participation and depressive symptoms among older adults and to identify the individual characteristics among older adults expected to benefit the most from social participation.
Int Microbiol
September 2025
School of Basic Sciences, Technology and Engineering, National Open and Distance University, Pasto, Nariño, Colombia.
This study investigates the impact of a defined starter culture on the fermentation of cocoa beans and its influence on the production of volatile and non-volatile compounds related to sensory quality. A microbial consortium comprising Saccharomyces cerevisiae, Pichia kudriavzevii, Levilactobacillus brevis, and Acetobacter okinawensis was selected based on their enzymatic activity and acid regulation properties. Fermentation trials showed that the starter culture enhanced the synthesis of key volatile compounds, particularly esters and higher alcohols, such as 2-phenylethanol and 2-phenylethyl acetate, which contribute floral and fruity aromas.
View Article and Find Full Text PDFMultivariate Behav Res
September 2025
Department of Social Psychology and Methodology, Universidad Autonoma de Madrid, Madrid, Spain.
Wording effects, the systematic method variance arising from the inconsistent responding to positively and negatively worded items of the same construct, are pervasive in the behavioral and health sciences. Although several factor modeling strategies have been proposed to mitigate their adverse effects, there is limited systematic research assessing their performance with exploratory structural equation models (ESEM). The present study evaluated the impact of different types of response bias related to wording effects (random and straight-line carelessness, acquiescence, item difficulty, and mixed) on ESEM models incorporating two popular method modeling strategies, the correlated traits-correlated methods minus one (CTC[M-1]) model and random intercept item factor analysis (RIIFA), as well as the "do nothing" approach.
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