Age: A Moderating Effect on Cerebrospinal Fluid Fibroblast Growth Factor 21 and Cognitive Function.

Background: Fibroblast growth factors(FGF)19 subclass related to endocrine metabolism, including FGF19, FGF21, and FGF23, which is associated with cognition. Age can affect its secretion and has been identified as a significant risk factor for cognitive decline. Consequently, age may moderate the impact of the FGF19 subclass on cognitive function.

Neutrophil green inclusions combined with hemophagocytosis in peripheral blood after bee sting a case report and literature review.

Rationale: Neutrophils green inclusions serve as sensitive biomarkers for acute liver failure and lactic acidosis, demonstrating a strong correlation with short-term mortality, commonly referred to as "death inclusions." The combination of macrophage phagocytosis with neutrophil green inclusion is rarely reported, and this article discusses the clinical association and prognostic value of these 2 critical phenomena.

Patient Concerns: A 76-year-old female patient and an 82-year-old male patient both developed acute hepatic and renal failure, lactic acidosis, and multiple organ dysfunction syndrome following bee stings.

Effect of on the expression of hub genes in the treatment of gastric cancer.

Background: The aim of this study was to predict the target genes and pathways of (RA) in the treatment of gastric cancer (GC) by an bioinformatics analysis.

Methods: The Traditional Chinese Medicine System Pharmacology database was used to obtain the chemical components and target genes of RA. GC-related genes were downloaded from GeneCard website.

Procalcitonin in general internal medicine: a bibliometric analysis.

Background: Procalcitonin (PCT) plays an important role in the identification of bacterial infection and therapy guidance. The relevant literature is mainly classified under critical care medicine or infectious disease. The research status of PCT in general internal medicine (GIM) is currently unclear.

Relationship between cognitive impairment and serum amyloid β-protein, adiponectin, and C-reactive protein levels in type II diabetes patients.

Background: This study sought to explore the plausible mechanism of the cognitive impairment of patients with type 2 diabetes by analyzing the levels of serum amyloid β-protein (Aβl-42), adiponectin, and C-reactive protein (CRP).

Methods: Eighty-four patients diagnosed with type 2 diabetes and 60 healthy people were selected as the participants for this study. Clinical data were collected using self-made questionnaires.

Effects of resveratrol on bone metabolism and bone turnover related indexes in ovariectomized osteoporosis rats.

This study aimed to investigate the effects of resveratrol (RES) on bone metabolism and bone turnover related indexes in ovariectomized osteoporosis rats. 48 clean grade adult healthy unmated female SD rats were randomly divided into 6 groups, including normal control group (NCG), osteoporosis model group (OP MG), estrogen treatment group (17β-E2 group), RES low dose group (RES-L), RES medium-dose group (RES-M) and RES high dose group (RES-H). The rats in NCG and OP MG were given distilled water once a day and the rats in the other two groups were given 17β-E2 and resveratrol respectively.

Capillary blood reference intervals for platelet parameters in healthy full-term neonates in China.

Background: No consensus has been reached on capillary blood reference intervals for platelet parameters in full-term neonates. We aimed to establish neonatal capillary blood reference intervals for platelet parameters and evaluate influences of sex, gestational age and postnatal age on platelet parameters.

Methods: This study was a prospective investigation and implemented in 594 healthy full-term neonates from 12 to 84 h of age, using SYSMEX XN-9000 haematology automatic analyser by means of capillary blood.

Clinical Value of Combined Detection of CK-MB, MYO, cTnI and Plasma NT-proBNP in Diagnosis of Acute Myocardial Infarction.

Background: Acute myocardial infarction (AMI) is a serious life-threatening and common heart disease that is based on coronary atherosclerosis. The aim is to study the changes in the level of kinase isoenzyme (CK-MB), myoglobin (MYO), cardiac troponin I (cTnI), and plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) in patients with acute myocardial infarction (AMI) and the four indicators of joint detection clinical value for diagnosis of AMI.

Methods: Plasma NT-proBNP, CK-MB, MYO, and cTnI were detected by CLIA in 208 AMI patients (AMI group) and 115 non-AMI patients (control group).

Characterization of a new gene WX2 in Toxoplasma gondii.

Using hybridization techniques, we prepared the monoclonal antibody (Mab) 7C3-C3 against Toxoplasma gondii. The protection tests showed that the protein (Mab7C3-C3) inhibited the invasion and proliferation of T. gondii RH strain in HeLa cells.