Capillary blood reference intervals for platelet parameters in healthy full-term neonates in China.

BMC Pediatr

Department of Paediatric Haematology and Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei Province, People's Republic of China.

Published: October 2020


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Background: No consensus has been reached on capillary blood reference intervals for platelet parameters in full-term neonates. We aimed to establish neonatal capillary blood reference intervals for platelet parameters and evaluate influences of sex, gestational age and postnatal age on platelet parameters.

Methods: This study was a prospective investigation and implemented in 594 healthy full-term neonates from 12 to 84 h of age, using SYSMEX XN-9000 haematology automatic analyser by means of capillary blood. Reference intervals for platelet parameters were defined by an interval of 2.5th - 97.5th percentiles.

Results: Capillary reference interval for platelet count was (152-464) × 10/L. No significance was found between sex-divided reference intervals for platelet parameters. The values of platelet count changed minimally across gestational age (37-41 weeks) and postnatal age (12-84 h). Reference intervals for other platelet parameters were affected by these factors to a different extent.

Conclusions: We established capillary blood reference intervals for platelet parameters in the first days after birth of full-term neonates in China.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547422PMC
http://dx.doi.org/10.1186/s12887-020-02373-6DOI Listing

Publication Analysis

Top Keywords

reference intervals
28
intervals platelet
28
platelet parameters
28
capillary blood
20
blood reference
20
full-term neonates
16
platelet
10
reference
8
healthy full-term
8
neonates china
8

Similar Publications

Efficacy and Safety of Aldosterone Synthase Inhibitors for Resistant Hypertension: A Systematic Review and Meta-Analysis.

Rev Cardiovasc Med

August 2025

Department of Emergency Medicine, General Practice Medical Center, National Clinical Research Center for Geriatrics, West China Hospital, 610041 Chengdu, Sichuan, China.

Background: Compared to patients with controllable hypertension, those with resistant hypertension (RH) have a higher incidence of cardiovascular complications, including stroke, left ventricular hypertrophy, and congestive heart failure. Therefore, an urgent need exists for improved management and control, along with more effective medications. Aldosterone synthase inhibitors (ASIs) are newly emerging drugs that have gradually attracted an increasing amount of attention.

View Article and Find Full Text PDF

Background: Globally, acute myocardial infarction (AMI) is among the primary causes of mortality. The ideal approach for blood pressure (BP) management for patients experiencing ST-segment elevation myocardial infarction (STEMI) who receive percutaneous coronary intervention (PCI) remains a topic of ongoing debate. Current guidelines on BP management lack specific recommendations for STEMI patients undergoing PCI, resulting in substantial individual variability and uncertainties in clinical treatment strategies.

View Article and Find Full Text PDF

The Association Between Meteorological Factors and Rotavirus Gastroenteritis Incidence in Japan: A Time-Series Analysis.

Cureus

August 2025

Division of International Health, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, JPN.

Introduction Rotavirus is the principal pathogen responsible for acute gastroenteritis and severe diarrhea in children worldwide and remains a significant public health threat. However, studies on the association between rotavirus gastroenteritis epidemics and meteorological factors in Japan are still scarce. In this study, we aimed to quantify the short-term effects of meteorological factors on the incidence of rotavirus gastroenteritis in Japan using advanced time-series modeling approaches.

View Article and Find Full Text PDF

Background: The treatment of mandibular angle fractures remains controversial, particularly regarding the method of fixation. The primary aim of this study was to compare surgical outcomes following treatment with 1-plate versus 2-plate fixation across two oral and maxillofacial surgery clinics. The secondary aim was to evaluate associations between patient-, trauma-, and procedure-specific factors with postoperative complications and to identify high-risk patients for secondary osteosynthesis.

View Article and Find Full Text PDF

Background: Immigrants continue to face challenges after entering the labor market and remain overrepresented in '3-D jobs' (dirty, difficult, degrading). This study aims to investigate the differences in occupational injury due to accidents (OIA) among immigrants compared to native-born workers in Sweden, and to examine the role of migrant-specific and work factors in these differences.

Methods: This repeated cross-sectional study used nationwide registers including all gainfully employed individuals in 2004-2020 (average annual sample 4.

View Article and Find Full Text PDF