A multiplexed three-channel detection system for rapid home-based diagnosis of respiratory viruses.

Acute respiratory syndrome coronavirus (SARS-CoV-2), influenza A virus (Flu A), and influenza B virus (Flu B) are highly contagious pathogens that can cause similar clinical manifestations and often co-infect, posing significant challenges for differential diagnosis and disease management. Early and accurate detection of these viruses is crucial for curbing their respiratory transmission. Therefore, there is an urgent need to develop a reliable, rapid, sensitive, and user-friendly tool for detecting multiple respiratory pathogens.

Layered solid Brønsted acid for dynamic interfacial pH regulation toward durable zinc anodes.

Aqueous zinc-ion batteries (AZIBs) are promising candidates for large-scale grid energy storage due to their inherent safety, durability, and low cost. However, their practical performance is hampered by the hydrogen evolution reaction (HER) on the Zn anode, which causes unstable Zn/electrolyte interfacial pH values, resulting in the formation of byproducts and uncontrollable Zn dendrite growth. To address these issues, we developed a layered solid Brønsted acid HNbMoO·HO (HNM) for interfacial pH regulation and Zn anode protection.

Wettability-Dependent Damping of Droplet Vibrations on Solid Surfaces.

Oscillating sessile droplets on a plane, crucial in industrial applications like inkjet printing, spray cooling, and antifogging, present a long-standing challenge in determining viscous damping. Existing solutions are limited to first-order asymptotic approximations of hemispherical droplets, accounting only for viscous dissipation near the wall. Considering further the bulk dissipation that is usually neglected due to its higher-order effect, we obtain a two-term approximation of decay rates for pinned sessile droplets with different contact angles.

Stem nematode disease resistance-conferring gene identification in sweet potato using combined BSA-Seq and BSR-Seq analyses.

Stem nematode disease, the most prevalent of three major diseases in northern China, causes huge sweet potato production losses. In this study, the resistant (Zhenghong22) and sensitive (Longshu9) parents, and the F segregating population mixed pools (Resistant- and Sensitive-Mixed) having extreme resistance traits, were used for BSA-Seq, BSR-Seq, and transcriptomic analyses to locate stem nematode disease resistance-conferring genes in sweet potato. Transcriptome results indicated that ethylene and ABA were the main hormones involved in disease resistance regulation, with secondary metabolic pathways playing crucial roles.

Redox-active polymer/graphene composite anode for advanced aqueous zinc-ion batteries.

In this study, graphene-wrapped poly(1,4,5,8-naphthalenetetracarboxylic sulfonyl)imine (PNSI/EG) served as a redox-active anode material for aqueous zinc-ion batteries (AZIBs). It yielded a reversible and stable capacity of 173.3 mAh g at 0.

High-Efficiency Flexible Zn-Air Batteries Enabled by Agarose Based Oxygen Electrocatalyst and Gel Electrolyte Through Bidirectionally Synergistic Optimization Strategy.

Flexible Zn-air batteries (F-ZABs) typically suffer from limited cycle life due to sluggish oxygen electrocatalytic kinetics and unstable electrochemical interfaces. A bidirectionally synergistic strategy for profit is proposed from the unique elemental characteristics and molecular architecture of agarose to simultaneously construct a triple-doped N, P, O oxygen electrocatalyst with multiple active sites and gel electrolyte with exceptional mechanical robustness and weather resistance. The electrocatalyst demonstrates superior oxygen reduction reaction (ORR) activity (E = 0.

Mg-doped layered vanadates for high-energy zinc anode-based electrochromic devices.

Zinc anode-based electrochromic devices (ZECDs) demonstrate promising prospects in dual-functional electrochromic (EC)-energy storage systems due to their unique optical and energy retrieval properties. Vanadates are widely used in ZECDs due to their diverse color properties, but their cycling stability and kinetics are often hindered by the strong electrostatic interactions between Zn ions and the host vanadate lattice. In this study, we fabricated magnesium ion-doped layered vanadates (MVO) with effectively enlarged interlayer spacing, promoting rapid insertion/extraction of Zn.

Simultaneous measurement of temperature and pressure using deep-learning-assisted femtosecond laser-induced scattering technique.

Femtosecond laser-induced grating scattering (fs-LIGS) technique has emerged as a robust diagnostic technique for combustion flow field characterization, particularly in temperature and pressure measurements. This study investigates four deep learning architectures for the simultaneous prediction of gas-phase temperature and pressure from raw fs-LIGS signals, including fully connected neural networks (FCNN), convolutional neural networks (CNN), bidirectional long short-term memory networks (BiLSTM), and a hybrid CNN-BiLSTM model. All architectures demonstrated exceptional predictive accuracy, achieving mean percentage errors ranging from -3.

Carnosic Acid Attenuated the Motor Impairment by Bisphenol A is Related to the Regulation of Autophagy Through Parkin in In Vitro and In Vivo.

Bisphenol A (BPA) is an endocrine-disrupting compound linked to impairments in motor function and the manifestation of anxiety-like behaviors. The present study investigated the effects of carnosic acid (CA) on BPA-induced motor deficits and explored the role of parkin in the autophagic mechanism. First, C57BL/6 J male mice were orally administered with CA (5 mg/kg and 20 mg/kg) or RE (80 mg/kg rosemary extract) to test the motor function and anxiety-like behaviors in BPA (50 μg/kg) treatment.

Naringenin Attenuates Ox-LDL-induced Injury in HUVECs by Regulating Lipophagy Partly through the SOCE Pathway.

Objective: Naringenin (NAR) is a naturally occurring tiny molecule that has a significant role in lipid metabolism. However, the molecular mechanism by which NAR is involved in lipid metabolism to protect ECs is not clear. This study aims to investigate the effect of NAR on autophagy in oxidized low-density lipoprotein (ox-LDL)-treated human umbilical vein endothelial cells (HUVECs) and its potential molecular mechanisms.

A Sustainable and Scalable Approach for In Situ Induction of Gradient Nucleation Sites in Biomass-Derived Interface Layers for Ultra-Stable Aqueous Zinc Metal Batteries.

Aqueous zinc metal batteries are promising candidates for large-grid energy storage due to their safety, cost-effectiveness, and durability. However, challenges like dendrite growth, corrosion, and the hydrogen evolution reaction (HER) on the zinc anode hinder their performance. Herein, we propose a sustainable and scalable approach to form a copper gluconate@carboxymethyl chitosan@kaolin (CuCK) interface layer, inducing gradient nucleation sites via in situ galvanic and galvanostatic processes.

Tough MXene-Cellulose Nanofibril Ionotronic Dual-Network Hydrogel Films for Stable Zinc Anodes.

Developing ionotronic interface layers for zinc anodes with superior mechanical integrity is one of the efficient strategies to suppress the growth of zinc dendrites in favor of the cycling stability of aqueous zinc-ion batteries (AZIBs). Herein, we assembled robust 2D MXene-based hydrogel films cross-linked by 1D cellulose nanofibril (CNF) dual networks, acting as interface layers to stabilize Zn anodes. The MXene-CNF hydrogel films integrated multifunctionalities, including a high in-plane toughness of 18.

How hydrodynamic conditions dominate the microplastic footprint in the largest freshwater lake in China.

Understanding the migration and diffusion process of microplastics (MPs) in lakes is of great significance to the cumulative assessment of controlling land-based MP pollution. The MPs in the surface water of Poyang Lake were identified to be mainly composed of three representative particles (>91 %): polyethylene (PE) fiber, polypropylene (PP) fragment and PE film, and this study explored the migration process of different types of MPs in three flow regimes. The results show that MP particles migrate northward under the gravity flow and jacking flow.

Effect of volatile compounds produced by Wickerhamomyces anomalus induced with chitosan against blue mold disease in table grapes.

Antagonistic yeasts, such as Wickerhamomyces anomalus, produce volatile organic compounds (VOCs) that serve as antifungals or biostimulants. Previous studies have demonstrated the efficacy of W. anomalus VOCs in inhibiting fruit decay caused by pathogenic microorganisms.

Consistency, distinction, and potential metabolic crosstalk of nitrogen mobilization-related genes in silk production and silk gland biology.

The domesticated silkworm ( ) has evolved a highly efficient nitrogen utilization system to support silk production. The silk glands play a pleiotropic role in sequestering nitrogen resources for silk synthesis, mitigating aminoacidemia by assimilating free amino acids, and reallocating nitrogen during metamorphosis through programmed cell death. However, the specific functions of nitrogen metabolism-related genes in this process remain unclear.

The Super Enhancer-Driven Long Noncoding RNA PRKCQ-AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds.

Tumorigenic drivers of MYCN gene nonamplified neuroblastoma remain largely uncharacterized. Long noncoding RNAs (lncRNAs) regulate tumorigenesis, however, there is little literature on therapeutic targeting of lncRNAs with small molecule compounds. Here PRKCQ-AS1 is identified as the lncRNA most overexpressed in MYCN nonamplified, compared with MYCN-amplified, neuroblastoma cell lines.

Antifungal efficacy and mechanisms of BL06 against .

Sweet potato black rot caused by the pathogenic fungus is a destructive disease that can result in severe agricultural losses. This study explores the antifungal efficacy and underlying mechanisms of BL06 against . The plate antagonism assay revealed that BL06 significantly suppressed the radial growth of mycelia, achieving inhibition rates of 39.

Harmonic Fast One-Step Cut: An Efficient Strategy for Spectral Clustering Optimization.

Due to the excellent performance of spectral clustering (SC), it has been widely used in many fields of application. However, the high computational complexity and two successive steps have limited SC's development. In addition, the traditional SC is formulated to maximize the arithmetic mean of trace ratios which is dominated by the larger objectives and may reduce the recognition accuracy in practical applications.

Changes in Plant Biomass Are Driven by Persisting Plant Species, but Species Gains Drive Nematode Carbon Dynamics.

Global change drivers, such as shrub encroachment, alter above- and belowground communities, and the consequences of these changes for ecosystem functioning are largely unknown. We used the modified Price equation to quantify how the presence of shrubs alters the richness, composition, and abundance of plant and nematode communities and the resulting effects on ecosystem functioning (i.e.

Construction of Composite Microorganisms and Their Physiological Mechanisms of Postharvest Disease Control in Red Grapes.

Red grapes often suffer from postharvest diseases like blue mold and black mold caused by and . Biological control using beneficial yeasts and bacteria is an effective method to manage these diseases. sp.

All-natural charge gradient interface for sustainable seawater zinc batteries.

Paring seawater electrolyte with zinc metal electrode has emerged as one of the most sustainable alternative solutions for offshore stationary energy storages owing to the intrinsic safety, extremely low cost, and unlimited water source. However, it remains a substantial challenge to stabilize zinc metal negative electrode in seawater electrolyte, given the presence of chloride ions and complex cations in seawater. Here, we reveal that chloride pitting initiates negative electrode corrosion and aggravates dendritic deposition, causing rapid battery failure.

Alginate oligosaccharide induces resistance against Penicillium expansum in pears by priming defense responses.

The research intended to explore the control ability of alginate oligosaccharide (AOS) on Penicillium expansum infection in pear fruit by priming response and its mechanism. The results showed that 100 mg L AOS treatment could significantly reduce the incidence of postharvest blue mold and the lesion diameter in pear fruits and maintain their quality. The defense responses induced by AOS treatment alone were relatively mild in pear fruits.

Selective Interface Engineering with Large π-Conjugated Molecules Enables Durable Zn Anodes.

Undesirable dendrite growth and side reactions at the electrical double layer (EDL) of Zn/electrolyte interface are critical challenges limiting the performance of aqueous zinc ion batteries. Through density functional theory calculations, we demonstrate that grafting large π-conjugated molecules (e.g.

Transcriptomic modifications across the genome and potential hazards of pulmonary fibrosis caused by metal-organic frameworks.

Metal-Organic Frameworks (MOFs) have shown great promise in environmental protection, owing to their exceptional properties including ultrahigh surface area and porosity, tunable pore size, and easy chemical functionalization. However, emerging evidence from experimental studies indicates that MOFs have side effects on human health due to metal ions doping, resulting in excessive reactive oxygen species (ROS) production, pro-inflammatory responses, and liver fibrosis. In this study, we investigated the impact of MOF-199 on human bronchial epithelial (HBE) cells by using transcriptome sequencing analysis.