Twist deformation response of a holographic volume grating in flexible photopolymer.

Twist deformation of flexible photopolymer using a diffraction spectrum of a holographic volume grating is explored. Twist deformation can be categorized into transverse shear and macroscopic twist deformations. At a small twist angle, the transverse shear deformation can be considered as a tiny unit of twist deformation.

Dynamic interfacial structure of au/CeO catalyst upon thermal activation.

The dynamic behavior of oxide-supported metal catalyst interfaces under thermal and gaseous activation critically determines their catalytic performance. Using in situ TEM, we reveal the atomic-scale evolution of Au nanoparticles on CeO supports during thermal treatment. The Au/CeO interface structure depends on three key factors: epitaxial matching, nanoparticle morphology, and metal-support interactions, all governed by the balance between Au surface energy, cohesive energy, and interfacial energy with CeO.

Association between serum chloride and prevalence of metabolic syndrome in the general U.S. adult population: evidence from NHANES 2011-2018.

Aim: Numerous studies have revealed the decisive role of serum chloride in the outcome of specific patients. However, the potential role of serum chloride in general populations has been rarely investigated. This study aims to assess the association of serum chloride with MetS risk in the general population.

Tanshinone IIA Reverses Osteogenic Differentiation of Bone Marrow Mesenchymal Stromal Cells Impaired by Glucocorticoids via the ERK1/2-CREB Signaling Pathway.

Glucocorticoids-induced osteoporosis poses a critical health issue due to its detrimental impact on bone marrow mesenchymal stem cells (BMSCs); Tanshinone IIA (TSA) emerges as a promising therapeutic intervention, demonstrating its capacity to reverse osteogenic differentiation impairment. The aim is to determine whether TSA enhances the osteogenic differentiation of BMSCs damaged by dexamethasone (DEX) through the ERK1/2 -CREB signaling pathway. BMSCs were treated with varying concentrations of DEX (0.

Gastric inflammatory myofibroblastic tumor invading the esophagus and spleen: a rare case report and literature review.

Inflammatory myofibroblastic tumor (IMT) is a rare neoplasm with intermediate biological potential. The stomach is an uncommon site for IMTs, and gastric IMTs are typically confined to the submucosal layer. This report presents a rare case of a 29-year-old woman with a gastric IMT located in the gastric fundus, exhibiting local invasion into the esophagus and spleen.

A novel cellulose-derived graphite carbon/ZnO composite by atomic layer deposition as an over-wideband microwave absorbent.

It is a major challenge to obtain broadband microwave absorption (MA) properties using low dielectric or magnetic nanoparticle-decorated carbon composites due to the limited single conductive loss or polarization loss of the carbon materials used as substrates. Novel pure cellulose-derived graphite carbon (CGC) materials can be used as an exceptional substrate option due to their special defective graphitic carbon structure, which provides both conduction and polarization loss. Herein, CGC@ZnO composites were first synthesized by atomic layer deposition (ALD) for use as microwave absorbents.

Development and Validation of a Nutritional Frailty Phenotype for Older Adults Based on Risk Prediction Model: Results from a Population-Based Prospective Cohort Study.

Objectives: Malnutrition is generally studied to be involved in outlining hazard frailty trajectories, resulting in adverse outcomes. In view of frailty's multidimensional nature, we aimed to assess the contribution of nutritional items in existing frailty tools to adverse outcomes, and develop and validate a nutritional frailty phenotype based on machine learning.

Design: A population-based prospective cohort study.

The impact of Benzophenone-3 on osteoarthritis pathogenesis: a network toxicology approach.

Background: Arthritis is a degenerative joint disease influenced by various environmental factors, including exposure to Benzophenone-3 (BP3), a common UV filter. This study aims to elucidate the toxicological impact of BP3 on arthritis pathogenesis using network toxicology approaches.

Method: We integrated data from the Comparative Toxicogenomics Database (CTD) and Gene Expression Omnibus (GEO) to identify differentially expressed BP3-related toxicological targets in osteoarthritis (OA).

Integrative bioinformatics analysis reveals novel insights into osteoarthritis pathogenesis and diagnostic biomarkers.

Background: Osteoarthritis (OA) is a prevalent joint disorder characterized by degeneration and inflammation. Understanding its molecular mechanisms is crucial for diagnosis and treatment.

Methods: We employed bioinformatics analyses to study OA using gene expression data.

Calcium bridges built by mitochondria-associated endoplasmic reticulum membranes: potential targets for neural repair in neurological diseases.

The exchange of information and materials between organelles plays a crucial role in regulating cellular physiological functions and metabolic levels. Mitochondria-associated endoplasmic reticulum membranes serve as physical contact channels between the endoplasmic reticulum membrane and the mitochondrial outer membrane, formed by various proteins and protein complexes. This microstructural domain mediates several specialized functions, including calcium (Ca 2+ ) signaling, autophagy, mitochondrial morphology, oxidative stress response, and apoptosis.

17β-estradiol activates SOX6 to balance the anabolism and catabolism via estrogen receptor 2 in chondrocyte.

We investigated the influence of 17β-estradiol (17β-E2) on cartilage extracellular matrix (ECM) homeostasis in postmenopausal women. We focused on the roles of estrogen receptors (ESR) and SOX6 in 17β-E2-mediated stimulation of ECM metabolism during chondrocyte (CH) degeneration. We compared the expression of anabolic genes (collagen II and aggrecan) and catabolic genes (MMPs and TIMPs) in IL-1β-induced CH degeneration in vitro, with and without 17β-E2 supplementation.

Fully automatic AI segmentation of oral surgery-related tissues based on cone beam computed tomography images.

Accurate segmentation of oral surgery-related tissues from cone beam computed tomography (CBCT) images can significantly accelerate treatment planning and improve surgical accuracy. In this paper, we propose a fully automated tissue segmentation system for dental implant surgery. Specifically, we propose an image preprocessing method based on data distribution histograms, which can adaptively process CBCT images with different parameters.

Mn(II) Coordination Complex Loaded Hydrogel: Synthesis, Characterization, Fluorescence Properties, and Application in Treating Knee Arthritis.

Using a mixed-ligand approach, we successfully obtained two Mn(II)-based coordination compounds, namely [Mn(L1)(TBIP)·HO]n (1) and [Mn(L2)(NPTA)·HO]n (2) (where L1 and L2 are 1,4-bis(thiabenzimidazol-1-ylmethyl)benzene and 1,2-bis(thiabenzimidazol-1-ylmethyl)benzene, HNPTA is 2-nitroterephthalic acid, and HTBIP is 5-tert-butylisophthalic acid). Fluorescence performance testing of complexes 1 and 2 showed excellent green and blue fluorescence properties. Based on this, we further prepared HA/CMCS hydrogels using natural polysaccharides hyaluronic acid (HA) and carboxymethyl chitosan (CMCS) as raw materials and studied their internal structural characteristics using scanning electron microscopy.

Novel Autophagy-Related Blood Biomarkers Associated with Immune Cell Infiltration in Ankylosing Spondylitis.

Background: This study aims to identify new therapeutic targets and explore the molecular mechanism of ankylosing spondylitis (AS), a rheumatic immune disease that mainly affects the sacroiliac and spinal joints. Despite extensive research, the exact cause of AS is still unknown. The research team utilized a bioinformatics approach to achieve their objectives.

Deciphering the Metal-Support Interaction of Au/ZnO Catalyst Induced by H and O Pretreatment.

Metal-support interaction (MSI) provides great possibilities to tune the activity, selectivity, and stability of heterogeneous catalysts. Herein, the Au/ZnO catalyst is prepared by commercial ZnO and chloroauric acid, and the structure evolution of the catalyst pretreated by H and O gas at varied temperature is investigated to provide mechanistic insights of MSI. It is found that the H treatment at 300 °C and above can induce the formation of both the ZnO overlayer and bulk Au-Zn alloy.

Development and validation of a preliminary clinical support system for measuring the probability of incident 2-year (pre)frailty among community-dwelling older adults: A prospective cohort study.

Objective: To develop the wed-based system for predicting risk of (pre)frailty among community-dwelling older adults.

Materials And Methods: (Pre)frailty was determined by physical frailty phenotype scale. A total of 2802 robust older adults aged ≥60 years from the China Health and Retirement Longitudinal Study (CHARLS) 2013-2015 survey were randomly assigned to derivation or internal validation cohort at a ratio of 8:2.

Temperature effects on axial dispersion in a photopolymer-based holographic lens.

This study aims to discover whether temperature has an effect on axial dispersion in a photopolymer-based holographic lens. A typical coaxial holographic lens is recorded in the acrylamide polymer system. The axial dispersion spectrum is read and collected by using a supercontinuum source and spectrometer.

Development and validation of risk prediction model for identifying 30-day frailty in older inpatients with undernutrition: A multicenter cohort study.

Objective: To develop and externally validate a frailty prediction model integrating physical factors, psychological variables and routine laboratory test parameters to predict the 30-day frailty risk in older adults with undernutrition.

Methods: Based on an ongoing survey of geriatrics syndrome in elder adults across China (SGSE), this prognostic study identified the putative prognostic indicators for predicting the 30-day frailty risk of older adults with undernutrition. Using multivariable logistic regression analysis with backward elimination, the predictive model was subjected to internal (bootstrap) and external validation, and its calibration was evaluated by the calibration slope and its C statistic discriminative ability.

Elucidation of the Key Therapeutic Targets and Potential Mechanisms of Marmesine against Knee Osteoarthritis via Network Pharmacological Analysis and Molecular Docking.

Background: Marmesine, a major active ingredient isolated from (Duhuo), has been reported to have multiple pharmacological activities. However, its therapeutic effects against knee osteoarthritis (OA) remain poorly investigated. The present study is aimed at uncovering the core targets and signaling pathways of marmesine against osteoarthritis using a combined method of bioinformatics and network pharmacology.

Effects of aromatherapy on fatigue, quality of sleep and quality of life in patients with inflammatory bowel disease: A feasibility study.

Background: Fatigue, poor sleep quality and poor quality of life (QoL) are recognised as common problems for patients with inflammatory bowel disease (IBD). This study aimed to evaluate feasibility and effect of aromatherapy on these problems in patients with IBD.

Methods: Seventy IBD patients from a tertiary hospital in China were randomly assigned to an intervention group and a control group.

Oral Immunization With a M Cell-Targeting Recombinant Vaccine LL-plSAM-FVpE Stimulate Protective Immunity Against in Mice.

There are many virulence factors of that contribute in diverse ways to gastric disease. Therefore, designing multivalent epitope vaccines against many key virulence factors virulence factors of is a promising strategy to control infection. In previous studies, we constructed a multivalent epitope vaccine FVpE against four key virulence factors of (Urease, CagA, VacA, and NAP), and oral immunization with the FVpE vaccine plus a polysaccharide adjuvant (PA) containing polysaccharide and chitosan could provide protection against infection in the Mongolian gerbil model.

Pyrolysis Characteristics of Indonesian Oil Sand in a Fixed Bed.

In this research, pyrolysis experiment of Indonesian oil sand was performed in a fixed bed. Results show that the temperature and heating rate had significant effects on the pyrolysis products. Data studied include yields of products and the gaseous product composition of carbon monoxide, hydrogen, methane, and other hydrocarbons.

Revealing synergetic structural activation of a CuAu surface during water-gas shift reaction.

Bimetallic alloy catalysts show strong structural and compositional dependence on their activity, selectivity, and stability. Often referred to as the “synergetic effect” of two metal elements in the alloys, their detailed dynamic information, structurally and chemically, of catalyst surface under reaction conditions remains largely elusive. Here, using aberration-corrected environmental transmission electron microscopy, we visualize the atomic-scale synergetic surface activation of CuAu under a water–gas shift reaction condition.

Nutritional Status According to the Short-Form Mini Nutritional Assessment (MNA-SF) and Clinical Characteristics as Predictors of Length of Stay, Mortality, and Readmissions Among Older Inpatients in China: A National Study.

Background: Studies are scarce in China that explore the association of nutritional status, measured using the Short-Form Mini Nutritional Assessment (MNA-SF) and biochemical data, on adverse clinical outcomes among older inpatients. In this study, we aimed to determine the prevalence of malnutrition in tertiary hospitals of China and the associations between malnutrition and adverse clinical outcomes.

Methods: This prospective study involved 5,516 older inpatients (mean age 72.

Nutritional Risk, Health Outcomes, and Hospital Costs Among Chinese Immobile Older Inpatients: A National Study.

Evidence of the impact of nutritional risk on health outcomes and hospital costs among Chinese older inpatients is limited. Relatively few studies have investigated the association between clinical and cost outcomes and nutritional risk in immobile older inpatients, particularly those with neoplasms, injury, digestive, cardiac, and respiratory conditions. This China-wide prospective observational cohort study comprised 5,386 immobile older inpatients hospitalized at 25 hospitals.