Strong second-harmonic generation response in an organic-inorganic hybrid antimony bromide.

A new organic-inorganic hybrid antimony bromide has been prepared using planar nicotinic acid as a structure-directing agent. The compound features a one-dimensional perovskite structure with a strong second-harmonic generation response (SHG) of 3.7 times that of KHPO.

Phenylpropanoids metabolism: recent insight into stress tolerance and plant development cues.

The phenylpropanoid pathway remains a key target for most climate-resilient crop development, owing to it being a precursor to over 8000 metabolites, including flavonoids and lignin compounds, including their derivatives. These metabolites are involved in biotic and abiotic stress tolerance, inviting several studies into their roles in plant defense, drought, temperature, UV, and nutrient stress tolerance. Literature is currently inundated with cutting-edge reports on the phenylpropanoid pathways and their functions.

Dual Chemical Scissors Strategy Enables 1D Antimony Selenates with Ultraviolet Nonlinear Optical Properties.

The rational, function-driven design of advanced inorganic functional materials remains a significant challenge, primarily attributed to their inherently complex and highly connected 3D frameworks of most oxide-based systems. Herein, we report a "dual chemical scissors" strategy that synergistically combines the effects of fluoride ions and stereochemically active lone pairs to precisely modulate local coordination environments and enable controlled dimensional reduction. Using this approach, we successfully synthesized the first series of non-centrosymmetric 1D antimony selenates-RbSbFSeO (I), RbSbFSeO (II), and RbSbFSeO (III).

Association between family history and onset age of cancer in China.

Background: Family history (FH) of cancer is an established risk factor for early onset of cancer. However, reliable estimates on the difference in onset age between familial and sporadic cancers remain scarce in the Chinese population.

Methods: This multicenter, hospital-based, cross-sectional study included 23 hospitals across 12 provinces.

The global progress and quality assessment of research on the association between circulating tumor DNA and clinical prognosis: a systematic review.

Objective: Circulating tumor DNA (ctDNA) has shown potential as a prognostic biomarker in patients with solid tumors. This study aimed to systematically summarize the global application of ctDNA in the prognostic management of solid tumor patients and to evaluate the quality of the current studies.

Methods: PubMed, Web of Science, Embase, Cochrane Library, Scopus, and clinical trials.

Circulating tumor DNA as a biomarker of prognosis prediction in colorectal cancer: a systematic review and meta-analysis.

Objective: Circulating tumor DNA (ctDNA) is increasingly being used as a potential biomarker in colorectal cancer (CRC) patients. However, the role of ctDNA in CRC prognosis prediction remains unclear. The objective is to systematically assess the clinical value of ctDNA in colorectal cancer prognosis prediction throughout the treatment cycle.

Halogen-Driven Structural Engineering in Tellurium Oxyhalides: Enhanced SHG Response and Broad Optical Transparency.

Oxyhalides are promising candidates for nonlinear optical (NLO) applications due to their unique structural and optical properties. In this study, we report the synthesis of two tellurium-based oxyhalides, TeOCl and TeOCl, which exhibit distinct structural features and exceptional optical performance. TeOCl crystallizes in a noncentrosymmetric 2D layered structure, while TeOCl adopts a centrosymmetric 1D chain arrangement.

Global landscape and trends in lifetime risks of haematologic malignancies in 185 countries: population-based estimates from GLOBOCAN 2022.

Background: Haematologic malignancies accounted for 6.6% of total cancer cases and 7.2% of total cancer-related deaths worldwide in 2022.

Second-Harmonic Generation in Organic-Inorganic Hybrid Cadmium Thiocyanates Containing Terminal Amino Acids.

Using chiral amino acids as terminal ligands, colorless crystals of Cd(SCN)(l-CHNO)(HO)·0.5CHOH () and Cd(SCN)(l-CHNO) () were obtained by a solvent evaporation method. Compound has a layered structure with a moderate second harmonic generation (SHG) efficiency (0.

In Situ Synthesis of Highly Emissive Manganese Halides with Modified Bisphosphonium Cations toward Information Encryption.

Multisite modulation for organic-inorganic hybrid metal halides (OIMHs) plays an important role in the optimization of their photophysical performance. Herein, we proposed an organic cation modification strategy on the phosphorus sites based on 1,2-Bis(diphenylphosphino)ethane (DPPE) by a simple one-pot solvothermal method. Three zero-dimensional (0D) manganese-based OIMHs, two novel MdppeMnCl·HO and EdppeMnCl, as well as the byproduct [Mn(dppeO)][MnCl] were obtained (Mdppe = methyl-coordinated with DPPE; Edppe = ethyl-coordinated with DPPE; and dppeO is obtained by oxidation of DPPE).

Design and Synthesis of Two Sn-Centered Mixed Halide Crystals with Enhanced Birefringence.

Enhancing the optical anisotropy of compounds has attracted significant interest in the optical field. Sn-centered crystals, containing stereochemically active lone pairs, are widely regarded as promising birefringent materials. In this study, we successfully synthesized two novel Sn-centered mixed halide birefringent crystals, NaSnFBr and NaSnFI.

Clinicopathological and therapeutic comparisons of esophageal cancer between China and the USA: a multicenter hospital-based study.

Background: Esophageal cancer (EC) remains a global health challenge due to its poor prognosis. China and the United States of America (USA) represent two distinct epicenters of EC burden. Understanding the EC disparities in these two countries is vital for tailoring prevention strategies, optimizing treatment, and enhancing outcomes in both countries.

Two l-Proline Cadmium Thiocyanates with Moderate Second-Harmonic-Generation Responses and Large Birefringences.

Two organic-inorganic cadmium thiocyanates, namely, Cd(SCN)(l-CHNO) () and Cd(SCN)(l-CHNO) (), have been synthesized using l-proline as the bridging ligand. The two compounds have double-chain-like and layered structures, respectively. They feature moderate second-harmonic-generation responses (0.

Transition towards cancer mortality predominance over cardiovascular disease mortality in Brazil, 2000-2019: a population-based study.

Background: Cardiovascular disease (CVD) and cancer are the first and second leading causes of death in Brazil and worldwide. However, an ongoing epidemiological transition in which cancer surpasses CVD has been observed in many high and middle-income countries. In this study, we provided a nationwide analysis of the transition towards cancer mortality predominance over CVD mortality in Brazil.

Cancer survival statistics in China 2019-2021: a multicenter, population-based study.

Background: A milestone goal of the Healthy China Program (2019-2030) is to achieve 5-year cancer survival at 43.3% for all cancers combined by 2022. To assess the progress towards this target, we analyzed the updated survival for all cancers combined and 25 specific cancer types in China from 2019 to 2021.

Incidence, mortality, and disability-adjusted life years of female breast cancer in China, 2022.

Background: Breast cancer is ranked among the most prevalent malignancies in the Chinese female population. However, comprehensive reports detailing the latest epidemiological data and attributable disease burden have not been extensively documented.

Methods: In 2018, high-quality cancer surveillance data were recorded in 700 population-based cancer registries in China.

l-Homoproline-Directed Synthesis of Organic-Inorganic Metal Iodides for Second Harmonic Generation.

Three organic-inorganic metal iodides, namely, (NH)(l-hp)ZnI (), [Cd(l-hp)]CdI (), and (l-Hhp)(l-hp)PbI (), have been synthesized using l-homoproline (l-hp) as the structure-directing agent. These compounds feature different noncentrosymmetric structures and optical properties. In particular, compound shows a large second-harmonic-generation response of 3.

YTHDF3 Regulates the Degradation and Stability of m6A-Enriched Transcripts to Facilitate the Progression of Castration-Resistant Prostate Cancer.

RNA N6-methyladenosine (m6A) readers mediate cancer progression. However, the functional role and potential mechanisms of the m6A readers in prostate cancer tumorigenicity remain to be elucidated. In this study, we demonstrate that YTHDF3 expression is elevated in castration-resistant prostate cancer (CRPC) and positively correlated to high grade, bone metastasis and poor survival.

Amine-directed synthesis, valence state control, and optical properties of two new organic-inorganic tin chlorides.

Two organic-inorganic tin chlorides, namely (CHNCl)SnCl (1) and (CHNCl)SnCl (2), were prepared valence state control using ,,','',''-pentamethyldiethylenetriamine as a structure-directing agent. The two compounds have zero-dimensional structures crystallized in non-centrosymmetric orthorhombic space group 2 and 222, respectively. In compound 1, the divalent tin ion forms a seesaw coordination configuration with four chloride ions, whereas in compound 2, the tetravalent tin ion forms an octahedral coordination configuration with six chloride ions.

Cancer incidence and mortality in China, 2022.

Background: The National Cancer Center (NCC) of China regularly reports the nationwide statistics on cancer incidence and mortality in China. The International Agency for Research on Cancer (IARC) calculates and publishes the cancer burden of countries around the world every two years. To ensure consistency between the actual surveillance data in China and the data published by IARC, NCC has received approval from the National Health Commission and IARC to simultaneously release the cancer burden data for China in GLOBOCAN 2022.