Low-Cost IMU-Based System for Automated Parkinson's Subtype and Stage Classification to Support Precision Rehabilitation.

Parkinson's disease (PD) is one of the most common progressive neurodegenerative disorder, for which early detection and precise rehabilitation planning are essential to alleviate its impact on quality of life and reduce societal burden. Accurate, automated PD subtype classification and staging play a key role in designing effective rehabilitation strategies while minimizing reliance on intensive expert assessments. Unlike existing automated methods that typically depend on high-cost medical imaging (e.

Mediterranean diet adherence and incident acute pancreatitis: a prospective cohort study.

Background: The relationship between Mediterranean diet (MedDiet) adherence and acute pancreatitis (AP) risk is largely unknown.

Objectives: To investigate the associations between MedDiet adherence and AP risk and joint associations of genetic risk and MedDiet adherence with AP risk.

Design: A prospective cohort study using data from UK Biobank, a large population-based prospective study that recruited over 500,000 participants aged 40-69 between 2006 and 2010 across the United Kingdom.

Low-κ Extension Doping for High-Performance Carbon Nanotube Transistors: Toward High-Speed, Energy-Efficient Electronics.

Carbon nanotubes (CNTs) present considerable potential as next-generation logic switches owing to their ultra-thin structure and exceptional electrical properties. Although recent advancements have achieved impressive direct current (DC) performance in individual devices, research on the architectural design of CNT-based transistors remains limited. This gap is critical, as device architecture directly influences power consumption and switching speed at the circuit level.

Shortening the Saturation Time of PBAT Sheet Foaming via the Pre-Introducing of Microporous Structures.

Poly (butylene adipate-co-terephthalate) (PBAT) foam sheets prepared by foaming supercritical fluids are characterized by high resilience, homogeneous cellular structure, and well-defined biodegradability. However, the inert chemical structure and the rigid hard segments restrict the diffusion of CO within the PBAT matrix, resulting in extremely long gas saturation times as long as 9 h at a thickness of 12 mm. In this study, microporous structures were pre-introduced into the PBAT matrix to provide a fast gas diffusion pathway during the saturation process.

Overcoming the Leakage and Contact Resistance Challenges in Highly Scaled PMOS and NMOS Carbon Nanotube Transistors.

In this work, we address the off-state leakage current challenge, while simultaneously demonstrating high drive current per CNT, in NMOS and PMOS carbon nanotube field-effect transistors (CNFETs). Increasing the bandgap from 0.6 to 0.

Adherence to the Mediterranean diet is associated with reduced chronic pancreatitis risk: a longitudinal cohort study.

: The role of diet on the risk of chronic pancreatitis (CP) is understudied. The health benefits of the Mediterranean diet (MedDiet) pattern have long been recognized, but its association with CP risk is unclear. We aimed to investigate the association between adherence to MedDiet and the incidence of CP in a large-scale cohort.

A Camel-Fur-Inspired Micro-Extrusion Foaming Porous Elastic Fiber for All-Weather Dual-Mode Human Thermal Regulation.

Maintaining the stability of human body temperature is the basis of ensuring the normal life activities of witness, and the emergence of various functional clothing is committed to assisting the human body temperature in thermal comfort range in the changeable environment. However, achieve dual-mode thermal regulation for cooling and insulation on an integrated material without energy input and addition of functional particles has thus far been a huge challenge. Herein, a biomimetic camel-fur designed micro-extruded physically foamed porous elastic fiber (MEPF) using thermoplastic polyurethane (TPU) elastomer as raw material is reported, and its dual-layered fabric (MEPFT-d) for effective personal thermal comfortable management at extreme temperature differences.

Comparative Study of the Foaming Behavior of Ethylene-Vinyl Acetate Copolymer Foams Fabricated Using Chemical and Physical Foaming Processes.

Ethylene-vinyl acetate copolymer (EVA), a crucial elastomeric resin, finds extensive application in the footwear industry. Conventional chemical foaming agents, including azodicarbonamide and 4,4'-oxybis(benzenesulfonyl hydrazide), have been identified as environmentally problematic. Hence, this study explores the potential of physical foaming of EVA using supercritical nitrogen as a sustainable alternative, garnering considerable interest in both academia and industry.

A Review of the Preparation of Porous Fibers and Porous Parts by a Novel Micro-Extrusion Foaming Technique.

This review introduces an innovative technology termed "Micro-Extrusion Foaming (MEF)", which amalgamates the merits of physical foaming and 3D printing. It presents a groundbreaking approach to producing porous polymer fibers and parts. Conventional methods for creating porous materials often encounter obstacles such as the extensive use of organic solvents, intricate processing, and suboptimal production efficiency.

Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models.

A major challenge to end the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is to develop a broadly protective vaccine that elicits long-term immunity. As the key immunogen, the viral surface spike (S) protein is frequently mutated, and conserved epitopes are shielded by glycans. Here, we revealed that S protein glycosylation has site-differential effects on viral infectivity.

The Chemical Compositions of Angelica pubescens Oil and Its Prevention of UV-B Radiation-Induced Cutaneous Photoaging.

Angelica pubescens, a plant of the family Umbelliferae, has been widely used as traditional Chinese medicine for the treatment of many diseases. However, there has been minimal modern research focused on the pharmacological activity of oils extracted from Angelica pubescens, in particular, the potential anti-photoaging effects. Therefore, in the present study, we analyzed the chemical composition of Angelica pubescens oil (AO) and evaluated its bioactivity against photoaging in ultraviolet (UV) -B radiation-induced hairless mice.

Comprehensive classification test of scapular dyskinesis: A reliability study.

Background: Assessment of scapular dyskinesis (SD) is of clinical interest, as SD is believed to be related to shoulder pathology. However, no clinical assessment with sufficient reliability to identify SD and provide treatment strategies is available.

Objectives: The purpose of this study was to investigate the reliability of the comprehensive SD classification method.

Effects of femoral rotational taping on pain, lower extremity kinematics, and muscle activation in female patients with patellofemoral pain.

Objectives: To explore the hip and knee joint kinematics as well as muscle activation between participants with patellofemoral pain syndrome (PFPS) and controls, and to investigate the immediate effect of proximal femoral rotational taping on pain, joint kinematics, and muscle activation during single-leg squat (SLS).

Design: Cross-sectional study.

Methods: Sixteen female participants with PFPS, and eight healthy female controls participated.

Shoulder physical activity, functional disability and task difficulties in patients with stiff shoulders: interpretation from RT3 accelerator.

We determined whether the degree of symptom-related functional disability was related to daily physical activity of the shoulder in subjects with stiff shoulders (SSs). Responsiveness and a clinically meaningful level of discrimination between improvement and non-improvement for shoulder physical activity (SPA) were determined. Twenty-six subjects with SSs participated.

EMG biofeedback effectiveness to alter muscle activity pattern and scapular kinematics in subjects with and without shoulder impingement.

Background: Muscle imbalance between serratus anterior (SA), upper trapezius (UA), middle trapezius (MT), and lower trapezius (LT) muscles has been observed in subjects with subacromial impingement syndrome (SAIS).

Objective: (1) To investigate the effect of electromyography (EMG) biofeedback training on muscle balance ratios and scapular kinematics in healthy adults and subjects with SAIS. (2) To investigate whether the effects of EMG biofeedback on muscle balance ratios are different between groups.

RT3 accelerometer shoulder activity: discrimination of activity levels by the RT3 accelerometer for the assessment of shoulder physical activity (SPA).

We investigated whether the RT3 accelerometer can be used to discriminate and characterize the different levels of shoulder physical activity (SPA) in both patients and healthy adults. Twenty healthy adults and 20 patients with shoulder disorders (SDs) performed activities at 5 levels of difficulty (easy, easy-moderate, moderate, hard-moderate, hard) with the same RT3 accelerometer fixed on the arm. The Vector Magnitude (VM) is the square root of the sum of squares from each axis to determine the overall magnitude of activity.

SUMO modifications control assembly of synaptonemal complex and polycomplex in meiosis of Saccharomyces cerevisiae.

The synaptonemal complex (SC) is a proteinaceous complex that apparently mediates synapsis between homologous chromosomes during meiotic prophase. In Saccharomyces cerevisiae, the Zip1 protein is the integral component of the SC. In the absence of a DNA double-strand break or the SC initiation protein Zip3, Zip1 proteins aggregate to form a polycomplex (PC).